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Results: 1 to 20 of 126

1.

Primary cilia regulate Gli/Hedgehog activation in pancreas.

Cervantes S, Lau J, Cano DA, Borromeo-Austin C, Hebrok M.

Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10109-14. doi: 10.1073/pnas.0909900107. Epub 2010 May 17.

PMID:
20479231
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Elevated Hedgehog/Gli signaling causes beta-cell dedifferentiation in mice.

Landsman L, Parent A, Hebrok M.

Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17010-5. doi: 10.1073/pnas.1105404108. Epub 2011 Oct 3.

PMID:
21969560
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes.

Tukachinsky H, Lopez LV, Salic A.

J Cell Biol. 2010 Oct 18;191(2):415-28. doi: 10.1083/jcb.201004108.

PMID:
20956384
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Characterization of primary cilia and Hedgehog signaling during development of the human pancreas and in human pancreatic duct cancer cell lines.

Nielsen SK, Møllgård K, Clement CA, Veland IR, Awan A, Yoder BK, Novak I, Christensen ST.

Dev Dyn. 2008 Aug;237(8):2039-52. doi: 10.1002/dvdy.21610.

PMID:
18629868
[PubMed - indexed for MEDLINE]
Free Article
5.

Primary cilia attenuate hedgehog signalling in neoplastic chondrocytes.

Ho L, Ali SA, Al-Jazrawe M, Kandel R, Wunder JS, Alman BA.

Oncogene. 2013 Nov 21;32(47):5388-96. doi: 10.1038/onc.2012.588. Epub 2012 Dec 17.

PMID:
23246966
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Ectopic overexpression of Sonic Hedgehog (Shh) induces stromal expansion and metaplasia in the adult murine pancreas.

Fendrich V, Oh E, Bang S, Karikari C, Ottenhof N, Bisht S, Lauth M, Brossart P, Katsanis N, Maitra A, Feldmann G.

Neoplasia. 2011 Oct;13(10):923-30.

PMID:
22028618
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.

Wen X, Lai CK, Evangelista M, Hongo JA, de Sauvage FJ, Scales SJ.

Mol Cell Biol. 2010 Apr;30(8):1910-22. doi: 10.1128/MCB.01089-09. Epub 2010 Feb 12.

PMID:
20154143
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Hedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult beta-cell function.

Lau J, Hebrok M.

Diabetes. 2010 May;59(5):1211-21. doi: 10.2337/db09-0914. Epub 2010 Feb 25.

PMID:
20185815
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved.

Chen MH, Wilson CW, Li YJ, Law KK, Lu CS, Gacayan R, Zhang X, Hui CC, Chuang PT.

Genes Dev. 2009 Aug 15;23(16):1910-28. doi: 10.1101/gad.1794109.

PMID:
19684112
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Stabilization of speckle-type POZ protein (Spop) by Daz interacting protein 1 (Dzip1) is essential for Gli turnover and the proper output of Hedgehog signaling.

Schwend T, Jin Z, Jiang K, Mitchell BJ, Jia J, Yang J.

J Biol Chem. 2013 Nov 8;288(45):32809-20. doi: 10.1074/jbc.M113.512962. Epub 2013 Sep 26.

PMID:
24072710
[PubMed - indexed for MEDLINE]
11.

Intraepithelial paracrine Hedgehog signaling induces the expansion of ciliated cells that express diverse progenitor cell markers in the basal epithelium of the mouse mammary gland.

García-Zaragoza E, Pérez-Tavarez R, Ballester A, Lafarga V, Jiménez-Reinoso A, Ramírez A, Murillas R, Gallego MI.

Dev Biol. 2012 Dec 1;372(1):28-44. doi: 10.1016/j.ydbio.2012.09.005. Epub 2012 Sep 20.

PMID:
23000969
[PubMed - indexed for MEDLINE]
Free Article
12.

The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia.

Caparrós-Martín JA, Valencia M, Reytor E, Pacheco M, Fernandez M, Perez-Aytes A, Gean E, Lapunzina P, Peters H, Goodship JA, Ruiz-Perez VL.

Hum Mol Genet. 2013 Jan 1;22(1):124-39. doi: 10.1093/hmg/dds409. Epub 2012 Oct 1.

PMID:
23026747
[PubMed - indexed for MEDLINE]
Free Article
13.

Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling.

Barakat B, Yu L, Lo C, Vu D, De Luca E, Cain JE, Martelotto LG, Dedhar S, Sadler AJ, Wang D, Watkins DN, Hannigan GE.

EMBO Rep. 2013 Sep;14(9):837-44. doi: 10.1038/embor.2013.110. Epub 2013 Jul 23. Erratum in: EMBO Rep. 2013 Oct;14(10):945. Martellotto, Luciano G [corrected to Martelotto, Luciano G].

PMID:
23877428
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.

Tuson M, He M, Anderson KV.

Development. 2011 Nov;138(22):4921-30. doi: 10.1242/dev.070805. Epub 2011 Oct 17.

PMID:
22007132
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Hedgehog signaling is required for effective regeneration of exocrine pancreas.

Fendrich V, Esni F, Garay MV, Feldmann G, Habbe N, Jensen JN, Dor Y, Stoffers D, Jensen J, Leach SD, Maitra A.

Gastroenterology. 2008 Aug;135(2):621-31. doi: 10.1053/j.gastro.2008.04.011. Epub 2008 Apr 16.

PMID:
18515092
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Tail wags dog: primary cilia and tumorigenesis.

Barakat MT, Scott MP.

Cancer Cell. 2009 Oct 6;16(4):276-7. doi: 10.1016/j.ccr.2009.09.019.

PMID:
19800572
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus.

Kim J, Kato M, Beachy PA.

Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21666-71. doi: 10.1073/pnas.0912180106. Epub 2009 Dec 8.

PMID:
19996169
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1.

Lu J, Chen M, Ren XR, Wang J, Lyerly HK, Barak L, Chen W.

PLoS One. 2013 May 3;8(5):e63353. doi: 10.1371/journal.pone.0063353. Print 2013.

PMID:
23671675
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation.

Clement CA, Kristensen SG, Møllgård K, Pazour GJ, Yoder BK, Larsen LA, Christensen ST.

J Cell Sci. 2009 Sep 1;122(Pt 17):3070-82. doi: 10.1242/jcs.049676. Epub 2009 Aug 4.

PMID:
19654211
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development.

Endoh-Yamagami S, Evangelista M, Wilson D, Wen X, Theunissen JW, Phamluong K, Davis M, Scales SJ, Solloway MJ, de Sauvage FJ, Peterson AS.

Curr Biol. 2009 Aug 11;19(15):1320-6. doi: 10.1016/j.cub.2009.06.046. Epub 2009 Jul 9.

PMID:
19592253
[PubMed - indexed for MEDLINE]
Free Article

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