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Results: 1 to 20 of 120

1.

MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis.

Najafi-Shoushtari SH, Kristo F, Li Y, Shioda T, Cohen DE, Gerszten RE, Näär AM.

Science. 2010 Jun 18;328(5985):1566-9. doi: 10.1126/science.1189123. Epub 2010 May 13.

PMID:
20466882
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

MicroRNAs in metabolism and metabolic diseases.

Rottiers V, Najafi-Shoushtari SH, Kristo F, Gurumurthy S, Zhong L, Li Y, Cohen DE, Gerszten RE, Bardeesy N, Mostoslavsky R, Näär AM.

Cold Spring Harb Symp Quant Biol. 2011;76:225-33. doi: 10.1101/sqb.2011.76.011049. Epub 2011 Dec 12.

PMID:
22156303
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRα expression and cholesterol homeostasis.

Adlakha YK, Khanna S, Singh R, Singh VP, Agrawal A, Saini N.

Cell Death Dis. 2013 Aug 29;4:e780. doi: 10.1038/cddis.2013.301.

PMID:
23990020
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

MiR-33 contributes to the regulation of cholesterol homeostasis.

Rayner KJ, Suárez Y, Dávalos A, Parathath S, Fitzgerald ML, Tamehiro N, Fisher EA, Moore KJ, Fernández-Hernando C.

Science. 2010 Jun 18;328(5985):1570-3. doi: 10.1126/science.1189862. Epub 2010 May 13.

PMID:
20466885
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

miR-33 links SREBP-2 induction to repression of sterol transporters.

Marquart TJ, Allen RM, Ory DS, Baldán A.

Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12228-32. doi: 10.1073/pnas.1005191107. Epub 2010 Jun 21.

PMID:
20566875
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo.

Horie T, Ono K, Horiguchi M, Nishi H, Nakamura T, Nagao K, Kinoshita M, Kuwabara Y, Marusawa H, Iwanaga Y, Hasegawa K, Yokode M, Kimura T, Kita T.

Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17321-6. doi: 10.1073/pnas.1008499107. Epub 2010 Sep 20.

PMID:
20855588
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Medicine. HDL miR-ed down by SREBP introns.

Brown MS, Ye J, Goldstein JL.

Science. 2010 Jun 18;328(5985):1495-6. doi: 10.1126/science.1192409. No abstract available.

PMID:
20558698
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Control of cholesterol metabolism and plasma high-density lipoprotein levels by microRNA-144.

Ramírez CM, Rotllan N, Vlassov AV, Dávalos A, Li M, Goedeke L, Aranda JF, Cirera-Salinas D, Araldi E, Salerno A, Wanschel A, Zavadil J, Castrillo A, Kim J, Suárez Y, Fernández-Hernando C.

Circ Res. 2013 Jun 7;112(12):1592-601. doi: 10.1161/CIRCRESAHA.112.300626. Epub 2013 Mar 21.

PMID:
23519695
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

MicroRNA-144 regulates hepatic ATP binding cassette transporter A1 and plasma high-density lipoprotein after activation of the nuclear receptor farnesoid X receptor.

de Aguiar Vallim TQ, Tarling EJ, Kim T, Civelek M, Baldán Á, Esau C, Edwards PA.

Circ Res. 2013 Jun 7;112(12):1602-12. doi: 10.1161/CIRCRESAHA.112.300648. Epub 2013 Mar 21.

PMID:
23519696
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

MicroRNAs regulating lipid metabolism in atherogenesis.

Rayner KJ, Fernandez-Hernando C, Moore KJ.

Thromb Haemost. 2012 Apr;107(4):642-7. doi: 10.1160/TH11-10-0694. Epub 2012 Jan 25. Review.

PMID:
22274626
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

MicroRNA-758 regulates cholesterol efflux through posttranscriptional repression of ATP-binding cassette transporter A1.

Ramirez CM, Dávalos A, Goedeke L, Salerno AG, Warrier N, Cirera-Salinas D, Suárez Y, Fernández-Hernando C.

Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2707-14. doi: 10.1161/ATVBAHA.111.232066.

PMID:
21885853
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR.

Wong J, Quinn CM, Brown AJ.

Biochem J. 2006 Dec 15;400(3):485-91.

PMID:
16901265
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting.

Quinet EM, Savio DA, Halpern AR, Chen L, Schuster GU, Gustafsson JA, Basso MD, Nambi P.

Mol Pharmacol. 2006 Oct;70(4):1340-9. Epub 2006 Jul 6.

PMID:
16825483
[PubMed - indexed for MEDLINE]
Free Article
14.

Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism.

Zeng L, Liao H, Liu Y, Lee TS, Zhu M, Wang X, Stemerman MB, Zhu Y, Shyy JY.

J Biol Chem. 2004 Nov 19;279(47):48801-7. Epub 2004 Sep 8.

PMID:
15358760
[PubMed - indexed for MEDLINE]
Free Article
15.

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides.

Rayner KJ, Esau CC, Hussain FN, McDaniel AL, Marshall SM, van Gils JM, Ray TD, Sheedy FJ, Goedeke L, Liu X, Khatsenko OG, Kaimal V, Lees CJ, Fernandez-Hernando C, Fisher EA, Temel RE, Moore KJ.

Nature. 2011 Oct 19;478(7369):404-7. doi: 10.1038/nature10486.

PMID:
22012398
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression.

Wagner BL, Valledor AF, Shao G, Daige CL, Bischoff ED, Petrowski M, Jepsen K, Baek SH, Heyman RA, Rosenfeld MG, Schulman IG, Glass CK.

Mol Cell Biol. 2003 Aug;23(16):5780-9.

PMID:
12897148
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Sphingolipid synthetic pathways are major regulators of lipid homeostasis.

Worgall TS.

Adv Exp Med Biol. 2011;721:139-48. doi: 10.1007/978-1-4614-0650-1_9. Review.

PMID:
21910087
[PubMed - indexed for MEDLINE]
18.

Polyphenol-rich black chokeberry (Aronia melanocarpa) extract regulates the expression of genes critical for intestinal cholesterol flux in Caco-2 cells.

Kim B, Park Y, Wegner CJ, Bolling BW, Lee J.

J Nutr Biochem. 2013 Sep;24(9):1564-70. doi: 10.1016/j.jnutbio.2013.01.005. Epub 2013 Mar 18.

PMID:
23517916
[PubMed - indexed for MEDLINE]
19.

Sterol regulatory element-binding protein-2- and liver X receptor-driven dual promoter regulation of hepatic ABC transporter A1 gene expression: mechanism underlying the unique response to cellular cholesterol status.

Tamehiro N, Shigemoto-Mogami Y, Kakeya T, Okuhira K, Suzuki K, Sato R, Nagao T, Nishimaki-Mogami T.

J Biol Chem. 2007 Jul 20;282(29):21090-9. Epub 2007 May 27.

PMID:
17526932
[PubMed - indexed for MEDLINE]
Free Article
20.

"Micromanaging" metabolic syndrome.

Ramírez CM, Goedeke L, Fernández-Hernando C.

Cell Cycle. 2011 Oct 1;10(19):3249-52. doi: 10.4161/cc.10.19.17558. Epub 2011 Oct 1.

PMID:
21946517
[PubMed - indexed for MEDLINE]
Free PMC Article

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