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Results: 1 to 20 of 84

1.

Epigenetics, the epicenter of the hypoxic response.

Watson JA, Watson CJ, McCann A, Baugh J.

Epigenetics. 2010 May 16;5(4):293-6. Epub 2010 May 3. Review.

PMID:
20418669
[PubMed - indexed for MEDLINE]
Free Article
2.

Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery: epigenetic regulation of the hypoxic response via hypoxia-inducible factor and histone modifying enzymes.

Mimura I, Tanaka T, Wada Y, Kodama T, Nangaku M.

J Pharmacol Sci. 2011;115(4):453-8. Epub 2011 Mar 16. Review.

PMID:
21422728
[PubMed - indexed for MEDLINE]
Free Article
3.

Activating transcription factor 2 increases transactivation and protein stability of hypoxia-inducible factor 1alpha in hepatocytes.

Choi JH, Cho HK, Choi YH, Cheong J.

Biochem J. 2009 Nov 11;424(2):285-96. doi: 10.1042/BJ20090371.

PMID:
19712049
[PubMed - indexed for MEDLINE]
Free Article
4.

Identification of novel small-molecule inhibitors of hypoxia-inducible factor-1 transactivation and DNA binding.

Jones DT, Harris AL.

Mol Cancer Ther. 2006 Sep;5(9):2193-202.

PMID:
16985052
[PubMed - indexed for MEDLINE]
Free Article
5.
6.

The insulin-PI3K/TOR pathway induces a HIF-dependent transcriptional response in Drosophila by promoting nuclear localization of HIF-alpha/Sima.

Dekanty A, Lavista-Llanos S, Irisarri M, Oldham S, Wappner P.

J Cell Sci. 2005 Dec 1;118(Pt 23):5431-41. Epub 2005 Nov 8.

PMID:
16278294
[PubMed - indexed for MEDLINE]
Free Article
7.

Regulation of HIF-1alpha at the transcriptional level.

Görlach A.

Curr Pharm Des. 2009;15(33):3844-52. Review.

PMID:
19671046
[PubMed - indexed for MEDLINE]
8.

A Key role for cyclic AMP-responsive element binding protein in hypoxia-mediated activation of the angiogenesis factor CCN1 (CYR61) in Tumor cells.

Meyuhas R, Pikarsky E, Tavor E, Klar A, Abramovitch R, Hochman J, Lago TG, Honigman A.

Mol Cancer Res. 2008 Sep;6(9):1397-409. doi: 10.1158/1541-7786.MCR-07-2086.

PMID:
18819928
[PubMed - indexed for MEDLINE]
Free Article
9.

Cellular signal transduction of the hypoxia response.

Nakayama K.

J Biochem. 2009 Dec;146(6):757-65. doi: 10.1093/jb/mvp167. Epub 2009 Oct 28. Review.

PMID:
19864435
[PubMed - indexed for MEDLINE]
10.

Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells.

Jung SN, Yang WK, Kim J, Kim HS, Kim EJ, Yun H, Park H, Kim SS, Choe W, Kang I, Ha J.

Carcinogenesis. 2008 Apr;29(4):713-21. doi: 10.1093/carcin/bgn032. Epub 2008 Feb 6.

PMID:
18258605
[PubMed - indexed for MEDLINE]
Free Article
11.

Effect of hypoxia-inducible factor-1alpha on transcription of survivin in non-small cell lung cancer.

Chen YQ, Zhao CL, Li W.

J Exp Clin Cancer Res. 2009 Feb 26;28:29. doi: 10.1186/1756-9966-28-29.

PMID:
19245702
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Persisting mild hypothermia suppresses hypoxia-inducible factor-1alpha protein synthesis and hypoxia-inducible factor-1-mediated gene expression.

Tanaka T, Wakamatsu T, Daijo H, Oda S, Kai S, Adachi T, Kizaka-Kondoh S, Fukuda K, Hirota K.

Am J Physiol Regul Integr Comp Physiol. 2010 Mar;298(3):R661-71. doi: 10.1152/ajpregu.00732.2009. Epub 2009 Dec 30.

PMID:
20042684
[PubMed - indexed for MEDLINE]
13.

Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways.

Elvidge GP, Glenny L, Appelhoff RJ, Ratcliffe PJ, Ragoussis J, Gleadle JM.

J Biol Chem. 2006 Jun 2;281(22):15215-26. Epub 2006 Mar 24.

PMID:
16565084
[PubMed - indexed for MEDLINE]
Free Article
14.

Hypoxia-induced expression of RTEF-1 (related transcriptional enhancer factor-1) in endothelial cells is independent of HIF-1 (hypoxia-inducible factor-1).

Zhang C, Song QH, Li J, Tian Y.

Biochem Biophys Res Commun. 2009 Apr 10;381(3):333-8. doi: 10.1016/j.bbrc.2009.02.083. Epub 2009 Feb 21. Retraction in: Biochem Biophys Res Commun. 2009 Oct 16;388(2):463.

PMID:
19236848
[PubMed - indexed for MEDLINE]
15.

Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation.

Zhang X, Zhou K, Wang R, Cui J, Lipton SA, Liao FF, Xu H, Zhang YW.

J Biol Chem. 2007 Apr 13;282(15):10873-80. Epub 2007 Feb 15.

PMID:
17303576
[PubMed - indexed for MEDLINE]
Free Article
16.

Hypoxia-induced epithelial VEGF-C/VEGFR-3 upregulation in carcinoma cell lines.

Simiantonaki N, Jayasinghe C, Michel-Schmidt R, Peters K, Hermanns MI, Kirkpatrick CJ.

Int J Oncol. 2008 Mar;32(3):585-92.

PMID:
18292935
[PubMed - indexed for MEDLINE]
17.

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1.

Forsythe JA, Jiang BH, Iyer NV, Agani F, Leung SW, Koos RD, Semenza GL.

Mol Cell Biol. 1996 Sep;16(9):4604-13.

PMID:
8756616
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Co-transactivation of the 3' erythropoietin hypoxia inducible enhancer by the HIF-1 protein.

Varma S, Cohen HJ.

Blood Cells Mol Dis. 1997 Aug;23(2):169-76.

PMID:
9236155
[PubMed - indexed for MEDLINE]
19.

Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha.

Puppo M, Battaglia F, Ottaviano C, Delfino S, Ribatti D, Varesio L, Bosco MC.

Mol Cancer Ther. 2008 Jul;7(7):1974-84. doi: 10.1158/1535-7163.MCT-07-2059.

PMID:
18645007
[PubMed - indexed for MEDLINE]
Free Article
20.

HIF-1 and HIF-2 transcription factors--similar but not identical.

Loboda A, Jozkowicz A, Dulak J.

Mol Cells. 2010 May;29(5):435-42. doi: 10.1007/s10059-010-0067-2. Epub 2010 Apr 12. Review.

PMID:
20396958
[PubMed - indexed for MEDLINE]
Free Article

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