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Results: 1 to 20 of 99

1.

Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier.

Miller DS.

Trends Pharmacol Sci. 2010 Jun;31(6):246-54. doi: 10.1016/j.tips.2010.03.003. Epub 2010 Apr 24. Review.

PMID:
20417575
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Constitutive androstane receptor upregulates Abcb1 and Abcg2 at the blood-brain barrier after CITCO activation.

Lemmen J, Tozakidis IE, Bele P, Galla HJ.

Brain Res. 2013 Mar 21;1501:68-80. doi: 10.1016/j.brainres.2013.01.025. Epub 2013 Jan 20.

PMID:
23340159
[PubMed - indexed for MEDLINE]
3.

Targeting regulation of ABC efflux transporters in brain diseases: a novel therapeutic approach.

Potschka H.

Pharmacol Ther. 2010 Jan;125(1):118-27. doi: 10.1016/j.pharmthera.2009.10.004. Epub 2009 Nov 5. Review.

PMID:
19896502
[PubMed - indexed for MEDLINE]
4.

Pregnane X receptor upregulates ABC-transporter Abcg2 and Abcb1 at the blood-brain barrier.

Lemmen J, Tozakidis IE, Galla HJ.

Brain Res. 2013 Jan 23;1491:1-13. doi: 10.1016/j.brainres.2012.10.060. Epub 2012 Nov 2.

PMID:
23123212
[PubMed - indexed for MEDLINE]
5.

Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy.

Miller DS, Bauer B, Hartz AM.

Pharmacol Rev. 2008 Jun;60(2):196-209. doi: 10.1124/pr.107.07109. Epub 2008 Jun 17. Review.

PMID:
18560012
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The ABC of the blood-brain barrier - regulation of drug efflux pumps.

Mahringer A, Ott M, Reimold I, Reichel V, Fricker G.

Curr Pharm Des. 2011;17(26):2762-70. Review.

PMID:
21827407
[PubMed - indexed for MEDLINE]
7.

Constitutive androstane receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier.

Wang X, Sykes DB, Miller DS.

Mol Pharmacol. 2010 Sep;78(3):376-83. doi: 10.1124/mol.110.063685. Epub 2010 Jun 14.

PMID:
20547735
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Subcellular localization of transporters along the rat blood-brain barrier and blood-cerebral-spinal fluid barrier by in vivo biotinylation.

Roberts LM, Black DS, Raman C, Woodford K, Zhou M, Haggerty JE, Yan AT, Cwirla SE, Grindstaff KK.

Neuroscience. 2008 Aug 13;155(2):423-38. doi: 10.1016/j.neuroscience.2008.06.015. Epub 2008 Jun 13.

PMID:
18619525
[PubMed - indexed for MEDLINE]
9.

Bioluminescent imaging of drug efflux at the blood-brain barrier mediated by the transporter ABCG2.

Bakhsheshian J, Wei BR, Chang KE, Shukla S, Ambudkar SV, Simpson RM, Gottesman MM, Hall MD.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20801-6. doi: 10.1073/pnas.1312159110. Epub 2013 Dec 2.

PMID:
24297888
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Functional induction of P-glycoprotein in the blood-brain barrier of streptozotocin-induced diabetic rats: evidence for the involvement of nuclear factor-kappaB, a nitrosative stress-sensitive transcription factor, in the regulation.

Maeng HJ, Kim MH, Jin HE, Shin SM, Tsuruo T, Kim SG, Kim DD, Shim CK, Chung SJ.

Drug Metab Dispos. 2007 Nov;35(11):1996-2005. Epub 2007 Jul 30.

PMID:
17664251
[PubMed - indexed for MEDLINE]
Free Article
11.

Regulation of ABC transporters at the blood-brain barrier: new targets for CNS therapy.

Hartz AM, Bauer B.

Mol Interv. 2010 Oct;10(5):293-304. doi: 10.1124/mi.10.5.6. Review.

PMID:
21045243
[PubMed - indexed for MEDLINE]
12.

Pregnane X receptor (PXR) regulates P-glycoprotein at the blood-brain barrier: functional similarities between pig and human PXR.

Ott M, Fricker G, Bauer B.

J Pharmacol Exp Ther. 2009 Apr;329(1):141-9. doi: 10.1124/jpet.108.149690. Epub 2009 Jan 15.

PMID:
19147857
[PubMed - indexed for MEDLINE]
Free Article
13.

Expression of ATP-binding cassette transporters at the inner blood-retinal barrier in a neonatal mouse model of oxygen-induced retinopathy.

Tagami M, Kusuhara S, Honda S, Tsukahara Y, Negi A.

Brain Res. 2009 Aug 4;1283:186-93. doi: 10.1016/j.brainres.2009.05.095. Epub 2009 Jun 6.

PMID:
19505448
[PubMed - indexed for MEDLINE]
14.

Efflux mechanisms at the developing brain barriers: ABC-transporters in the fetal and postnatal rat.

Ek CJ, Wong A, Liddelow SA, Johansson PA, Dziegielewska KM, Saunders NR.

Toxicol Lett. 2010 Aug 1;197(1):51-9. doi: 10.1016/j.toxlet.2010.04.025. Epub 2010 May 11.

PMID:
20466047
[PubMed - indexed for MEDLINE]
15.

In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation.

Bauer B, Yang X, Hartz AM, Olson ER, Zhao R, Kalvass JC, Pollack GM, Miller DS.

Mol Pharmacol. 2006 Oct;70(4):1212-9. Epub 2006 Jul 12.

PMID:
16837625
[PubMed - indexed for MEDLINE]
Free Article
16.

Expression of nuclear receptor mRNA and liver X receptor-mediated regulation of ABC transporter A1 at rat blood-brain barrier.

Akanuma S, Hori S, Ohtsuki S, Fujiyoshi M, Terasaki T.

Neurochem Int. 2008 Mar-Apr;52(4-5):669-74. Epub 2007 Aug 26.

PMID:
17919779
[PubMed - indexed for MEDLINE]
17.

ABC transporters during epilepsy and mechanisms underlying multidrug resistance in refractory epilepsy.

Lazarowski A, Czornyj L, Lubienieki F, Girardi E, Vazquez S, D'Giano C.

Epilepsia. 2007;48 Suppl 5:140-9. Review. Erratum in: Epilepsia. 2007 Dec;48(12):2380.

PMID:
17910594
[PubMed - indexed for MEDLINE]
18.

Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood-brain barrier.

Eisenblätter T, Hüwel S, Galla HJ.

Brain Res. 2003 May 9;971(2):221-31.

PMID:
12706238
[PubMed - indexed for MEDLINE]
19.

Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up.

Agarwal S, Hartz AM, Elmquist WF, Bauer B.

Curr Pharm Des. 2011;17(26):2793-802. Review.

PMID:
21827403
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier.

Dauchy S, Dutheil F, Weaver RJ, Chassoux F, Daumas-Duport C, Couraud PO, Scherrmann JM, De Waziers I, Declèves X.

J Neurochem. 2008 Dec;107(6):1518-28. doi: 10.1111/j.1471-4159.2008.05720.x.

PMID:
19094056
[PubMed - indexed for MEDLINE]

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