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Results: 1 to 20 of 115

1.

Thiopurine S-methyltransferase (TPMT) assessment prior to starting thiopurine drug treatment; a pharmacogenomic test whose time has come.

Ford LT, Berg JD.

J Clin Pathol. 2010 Apr;63(4):288-95. doi: 10.1136/jcp.2009.069252. Review.

PMID:
20354201
[PubMed - indexed for MEDLINE]
2.

Thiopurine S-methyltransferase polymorphisms: efficient screening method for patients considering taking thiopurine drugs.

Wusk B, Kullak-Ublick GA, Rammert C, von Eckardstein A, Fried M, Rentsch KM.

Eur J Clin Pharmacol. 2004 Mar;60(1):5-10. Epub 2004 Feb 24.

PMID:
14985890
[PubMed - indexed for MEDLINE]
3.

Current use of pharmacogenetic testing: a national survey of thiopurine methyltransferase testing prior to azathioprine prescription.

Fargher EA, Tricker K, Newman W, Elliott R, Roberts SA, Shaffer JL, Bruce I, Payne K.

J Clin Pharm Ther. 2007 Apr;32(2):187-95.

PMID:
17381669
[PubMed - indexed for MEDLINE]
4.

Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine.

Evans WE, Hon YY, Bomgaars L, Coutre S, Holdsworth M, Janco R, Kalwinsky D, Keller F, Khatib Z, Margolin J, Murray J, Quinn J, Ravindranath Y, Ritchey K, Roberts W, Rogers ZR, Schiff D, Steuber C, Tucci F, Kornegay N, Krynetski EY, Relling MV.

J Clin Oncol. 2001 Apr 15;19(8):2293-301.

PMID:
11304783
[PubMed - indexed for MEDLINE]
Free Article
5.

Assessment of thiopurine S-methyltransferase activity in patients prescribed thiopurines: a systematic review.

Booth RA, Ansari MT, Loit E, Tricco AC, Weeks L, Doucette S, Skidmore B, Sears M, Sy R, Karsh J.

Ann Intern Med. 2011 Jun 21;154(12):814-23, W-295-8. doi: 10.7326/0003-4819-154-12-201106210-00009. Review.

PMID:
21690596
[PubMed - indexed for MEDLINE]
6.

Efficient screening method of the thiopurine methyltransferase polymorphisms for patients considering taking thiopurine drugs in a Chinese Han population in Henan Province (central China).

Zhang LR, Song DK, Zhang W, Zhao J, Jia LJ, Xing DL.

Clin Chim Acta. 2007 Feb;376(1-2):45-51. Epub 2006 Jul 14.

PMID:
16952345
[PubMed - indexed for MEDLINE]
7.

Clinical utility of thiopurine S-methyltransferase genotyping.

Corominas H, Baiget M.

Am J Pharmacogenomics. 2004;4(1):1-8. Review.

PMID:
14987117
[PubMed - indexed for MEDLINE]
8.

Thiopurine S- methyltransferase [corrected] testing in idiopathic pulmonary fibrosis: a pharmacogenetic cost-effectiveness analysis.

Hagaman JT, Kinder BW, Eckman MH.

Lung. 2010 Apr;188(2):125-32. doi: 10.1007/s00408-009-9217-8. Erratum in: Lung. 2011 Jun;189(3):259.

PMID:
20066544
[PubMed - indexed for MEDLINE]
9.

Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: impact of thiopurine S-methyltransferase polymorphism.

Schwab M, Schäffeler E, Marx C, Fischer C, Lang T, Behrens C, Gregor M, Eichelbaum M, Zanger UM, Kaskas BA.

Pharmacogenetics. 2002 Aug;12(6):429-36.

PMID:
12172211
[PubMed - indexed for MEDLINE]
10.

No induction of thiopurine methyltransferase during thiopurine treatment in inflammatory bowel disease.

Lindqvist M, Hindorf U, Almer S, Söderkvist P, Ström M, Hjortswang H, Peterson C.

Nucleosides Nucleotides Nucleic Acids. 2006;25(9-11):1033-7.

PMID:
17065060
[PubMed - indexed for MEDLINE]
11.

Assessment of thiopurine methyltransferase activity in patients prescribed azathioprine or other thiopurine-based drugs.

Booth RA, Ansari MT, Tricco AC, Loit E, Weeks L, Doucette S, Skidmore B, Hoch JS, Tsouros S, Sears M, Sy R, Karsh J, Mani S, Galipeau J, Yurkiewich A, Daniel R, Tsertsvadze A, Yazdi F.

Evid Rep Technol Assess (Full Rep). 2010 Dec;(196):1-282. Review.

PMID:
23126559
[PubMed - indexed for MEDLINE]
Free Article
12.

Canine red blood cell thiopurine S-methyltransferase: companion animal pharmacogenetics.

Salavaggione OE, Kidd L, Prondzinski JL, Szumlanski CL, Pankratz VS, Wang L, Trepanier L, Weinshilboum RM.

Pharmacogenetics. 2002 Dec;12(9):713-24.

PMID:
12464800
[PubMed - indexed for MEDLINE]
13.

Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy?

Sanderson J, Ansari A, Marinaki T, Duley J.

Ann Clin Biochem. 2004 Jul;41(Pt 4):294-302. Review.

PMID:
15298741
[PubMed - indexed for MEDLINE]
14.

Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance.

Yates CR, Krynetski EY, Loennechen T, Fessing MY, Tai HL, Pui CH, Relling MV, Evans WE.

Ann Intern Med. 1997 Apr 15;126(8):608-14.

PMID:
9103127
[PubMed - indexed for MEDLINE]
15.

Thiopurine pharmacogenetics: clinical and molecular studies of thiopurine methyltransferase.

Weinshilboum R.

Drug Metab Dispos. 2001 Apr;29(4 Pt 2):601-5.

PMID:
11259360
[PubMed - indexed for MEDLINE]
Free Article
16.

Genotyping should be considered the primary choice for pre-treatment evaluation of thiopurine methyltransferase function.

Hindorf U, Appell ML.

J Crohns Colitis. 2012 Jul;6(6):655-9. doi: 10.1016/j.crohns.2011.11.014. Epub 2011 Dec 13.

PMID:
22398041
[PubMed - indexed for MEDLINE]
17.

Thiopurine S-methyltransferase genotype-phenotype concordance: used as a quality assurance tool to help control the phenotype assay.

Ford L, Kampanis P, Berg J.

Ann Clin Biochem. 2009 Mar;46(Pt 2):152-4. doi: 10.1258/acb.2008.008167. Epub 2009 Jan 22.

PMID:
19164342
[PubMed - indexed for MEDLINE]
18.

Thiopurine methyltransferase (TPMT) heterozygosity and enzyme activity as predictive tests for the development of azathioprine-related adverse events.

Heckmann JM, Lambson EM, Little F, Owen EP.

J Neurol Sci. 2005 Apr 15;231(1-2):71-80.

PMID:
15792824
[PubMed - indexed for MEDLINE]
19.

Whole-blood thiopurine S-methyltransferase activity with genotype concordance: a new, simplified phenotyping assay.

Ford L, Graham V, Berg J.

Ann Clin Biochem. 2006 Sep;43(Pt 5):354-60.

PMID:
17036413
[PubMed - indexed for MEDLINE]
20.

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