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Results: 1 to 20 of 106

1.

Suppressor of cytokine signaling-2 gene disruption promotes Apc(Min/+) tumorigenesis and activator protein-1 activation.

Newton VA, Ramocki NM, Scull BP, Simmons JG, McNaughton K, Lund PK.

Am J Pathol. 2010 May;176(5):2320-32. doi: 10.2353/ajpath.2010.090684. Epub 2010 Mar 26.

PMID:
20348236
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis.

Zeilstra J, Joosten SP, Dokter M, Verwiel E, Spaargaren M, Pals ST.

Cancer Res. 2008 May 15;68(10):3655-61. doi: 10.1158/0008-5472.CAN-07-2940.

PMID:
18483247
[PubMed - indexed for MEDLINE]
Free Article
3.

Haplotype insufficiency for suppressor of cytokine signaling-2 enhances intestinal growth and promotes polyp formation in growth hormone-transgenic mice.

Michaylira CZ, Ramocki NM, Simmons JG, Tanner CK, McNaughton KK, Woosley JT, Greenhalgh CJ, Lund PK.

Endocrinology. 2006 Apr;147(4):1632-41. Epub 2006 Jan 12.

PMID:
16410303
[PubMed - indexed for MEDLINE]
4.

Suppressor of cytokine signaling-2 limits intestinal growth and enterotrophic actions of IGF-I in vivo.

Michaylira CZ, Simmons JG, Ramocki NM, Scull BP, McNaughton KK, Fuller CR, Lund PK.

Am J Physiol Gastrointest Liver Physiol. 2006 Sep;291(3):G472-81. Epub 2006 Mar 30.

PMID:
16574995
[PubMed - indexed for MEDLINE]
Free Article
5.

Inhibition of intestinal polyposis with reduced angiogenesis in ApcMin/+ mice due to decreases in c-Myc expression.

Yekkala K, Baudino TA.

Mol Cancer Res. 2007 Dec;5(12):1296-303. doi: 10.1158/1541-7786.MCR-07-0232. Erratum in: Mol Cancer Res. 2008 Feb;6(2):340.

PMID:
18171987
[PubMed - indexed for MEDLINE]
Free Article
6.

Elevated Dnmt3a activity promotes polyposis in Apc(Min) mice by relaxing extracellular restraints on Wnt signaling.

Samuel MS, Suzuki H, Buchert M, Putoczki TL, Tebbutt NC, Lundgren-May T, Christou A, Inglese M, Toyota M, Heath JK, Ward RL, Waring PM, Ernst M.

Gastroenterology. 2009 Sep;137(3):902-13, 913.e1-11. doi: 10.1053/j.gastro.2009.05.042. Epub 2009 May 18.

PMID:
19454286
[PubMed - indexed for MEDLINE]
7.

Cables1 is a tumor suppressor gene that regulates intestinal tumor progression in Apc(Min) mice.

Arnason T, Pino MS, Yilmaz O, Kirley SD, Rueda BR, Chung DC, Zukerberg LR.

Cancer Biol Ther. 2013 Jul;14(7):672-8. doi: 10.4161/cbt.25089. Epub 2013 May 31.

PMID:
23792637
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation.

Hinoi T, Akyol A, Theisen BK, Ferguson DO, Greenson JK, Williams BO, Cho KR, Fearon ER.

Cancer Res. 2007 Oct 15;67(20):9721-30.

PMID:
17942902
[PubMed - indexed for MEDLINE]
Free Article
9.

Monoallelic silencing and haploinsufficiency in early murine intestinal neoplasms.

Amos-Landgraf JM, Irving AA, Hartman C, Hunter A, Laube B, Chen X, Clipson L, Newton MA, Dove WF.

Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2060-5. doi: 10.1073/pnas.1120753109. Epub 2012 Jan 23.

PMID:
22308460
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Inactivation of the vitamin D receptor in APC(min/+) mice reveals a critical role for the vitamin D receptor in intestinal tumor growth.

Zheng W, Wong KE, Zhang Z, Dougherty U, Mustafi R, Kong J, Deb DK, Zheng H, Bissonnette M, Li YC.

Int J Cancer. 2012 Jan 1;130(1):10-9. doi: 10.1002/ijc.25992. Epub 2011 Apr 20.

PMID:
21328347
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Deficiency of phospholipase A2 group 7 decreases intestinal polyposis and colon tumorigenesis in Apc(Min/+) mice.

Xu C, Reichert EC, Nakano T, Lohse M, Gardner AA, Revelo MP, Topham MK, Stafforini DM.

Cancer Res. 2013 May 1;73(9):2806-16. doi: 10.1158/0008-5472.CAN-12-2374. Epub 2013 Jan 29.

PMID:
23361301
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice.

Moran AE, Hunt DH, Javid SH, Redston M, Carothers AM, Bertagnolli MM.

J Biol Chem. 2004 Oct 8;279(41):43261-72. Epub 2004 Aug 4.

PMID:
15294912
[PubMed - indexed for MEDLINE]
Free Article
13.

Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation.

Yang K, Popova NV, Yang WC, Lozonschi I, Tadesse S, Kent S, Bancroft L, Matise I, Cormier RT, Scherer SJ, Edelmann W, Lipkin M, Augenlicht L, Velcich A.

Cancer Res. 2008 Sep 15;68(18):7313-22. doi: 10.1158/0008-5472.CAN-08-0598.

PMID:
18794118
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Transcriptional profiling of the transition from normal intestinal epithelia to adenomas and carcinomas in the APCMin/+ mouse.

Paoni NF, Feldman MW, Gutierrez LS, Ploplis VA, Castellino FJ.

Physiol Genomics. 2003 Nov 11;15(3):228-35.

PMID:
13130079
[PubMed - indexed for MEDLINE]
15.

Suppressor of cytokine signaling-2 deficiency induces molecular and metabolic changes that partially overlap with growth hormone-dependent effects.

Rico-Bautista E, Greenhalgh CJ, Tollet-Egnell P, Hilton DJ, Alexander WS, Norstedt G, Flores-Morales A.

Mol Endocrinol. 2005 Mar;19(3):781-93. Epub 2004 Nov 24.

PMID:
15563548
[PubMed - indexed for MEDLINE]
16.

Helicobacter hepaticus infection promotes colon tumorigenesis in the BALB/c-Rag2(-/-) Apc(Min/+) mouse.

Nagamine CM, Sohn JJ, Rickman BH, Rogers AB, Fox JG, Schauer DB.

Infect Immun. 2008 Jun;76(6):2758-66. doi: 10.1128/IAI.01604-07. Epub 2008 Apr 14.

PMID:
18411292
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways.

Luo F, Brooks DG, Ye H, Hamoudi R, Poulogiannis G, Patek CE, Winton DJ, Arends MJ.

Int J Exp Pathol. 2009 Oct;90(5):558-74. doi: 10.1111/j.1365-2613.2009.00667.x.

PMID:
19765110
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Tumor regionality in the mouse intestine reflects the mechanism of loss of Apc function.

Haigis KM, Hoff PD, White A, Shoemaker AR, Halberg RB, Dove WF.

Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9769-73. Epub 2004 Jun 21.

PMID:
15210940
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Hepatocyte growth factor activator inhibitor type 1 is a suppressor of intestinal tumorigenesis.

Hoshiko S, Kawaguchi M, Fukushima T, Haruyama Y, Yorita K, Tanaka H, Seiki M, Inatsu H, Kitamura K, Kataoka H.

Cancer Res. 2013 Apr 15;73(8):2659-70. doi: 10.1158/0008-5472.CAN-12-3337. Epub 2013 Feb 27.

PMID:
23447577
[PubMed - indexed for MEDLINE]
Free Article
20.

The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis.

Li Q, Ishikawa TO, Oshima M, Taketo MM.

Cancer Res. 2005 Oct 1;65(19):8622-7.

PMID:
16204028
[PubMed - indexed for MEDLINE]
Free Article

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