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Results: 1 to 20 of 101

1.

Genotype-based risk and pharmacogenetic sampling in clinical trials.

Schork NJ, Topol EJ.

J Biopharm Stat. 2010 Mar;20(2):315-33. doi: 10.1080/10543400903572779.

PMID:
20309761
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Genetic predisposition to obesity leads to increased risk of type 2 diabetes.

Li S, Zhao JH, Luan J, Langenberg C, Luben RN, Khaw KT, Wareham NJ, Loos RJ.

Diabetologia. 2011 Apr;54(4):776-82. doi: 10.1007/s00125-011-2044-5. Epub 2011 Jan 26.

PMID:
21267540
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Pharmacogenetics: potential role in the treatment of diabetes and obesity.

Vella A, Camilleri M.

Expert Opin Pharmacother. 2008 May;9(7):1109-19. doi: 10.1517/14656566.9.7.1109. Review.

PMID:
18422469
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease).

Roses AD, Saunders AM, Huang Y, Strum J, Weisgraber KH, Mahley RW.

Pharmacogenomics J. 2007 Feb;7(1):10-28. Epub 2006 Jun 13. Review.

PMID:
16770341
[PubMed - indexed for MEDLINE]
5.

Pharmacogenetics for genes associated with age-related macular degeneration in the Comparison of AMD Treatments Trials (CATT).

Hagstrom SA, Ying GS, Pauer GJ, Sturgill-Short GM, Huang J, Callanan DG, Kim IK, Klein ML, Maguire MG, Martin DF; Comparison of AMD Treatments Trials Research Group.

Ophthalmology. 2013 Mar;120(3):593-9. doi: 10.1016/j.ophtha.2012.11.037. Epub 2013 Jan 18.

PMID:
23337555
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers.

Jakobsdottir J, Gorin MB, Conley YP, Ferrell RE, Weeks DE.

PLoS Genet. 2009 Feb;5(2):e1000337. doi: 10.1371/journal.pgen.1000337. Epub 2009 Feb 6.

PMID:
19197355
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population.

Robiou-du-Pont S, Bonnefond A, Yengo L, Vaillant E, Lobbens S, Durand E, Weill J, Lantieri O, Balkau B, Charpentier G, Marre M, Froguel P, Meyre D.

Int J Obes (Lond). 2013 Jul;37(7):980-5. doi: 10.1038/ijo.2012.175. Epub 2012 Oct 23.

PMID:
23090577
[PubMed - indexed for MEDLINE]
8.

What will whole genome searches for susceptibility genes for common complex disease offer to clinical practice?

Lango H, Weedon MN.

J Intern Med. 2008 Jan;263(1):16-27. Review.

PMID:
18088250
[PubMed - indexed for MEDLINE]
9.

A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.

Ioannidis JP, Castaldi P, Evangelou E.

J Natl Cancer Inst. 2010 Jun 16;102(12):846-58. doi: 10.1093/jnci/djq173. Epub 2010 May 26. Review.

PMID:
20505153
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Variations in predicted risks in personal genome testing for common complex diseases.

Kalf RR, Mihaescu R, Kundu S, de Knijff P, Green RC, Janssens AC.

Genet Med. 2014 Jan;16(1):85-91. doi: 10.1038/gim.2013.80. Epub 2013 Jun 27.

PMID:
23807614
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

VEGFA and VEGFR2 gene polymorphisms and response to anti-vascular endothelial growth factor therapy: comparison of age-related macular degeneration treatments trials (CATT).

Hagstrom SA, Ying GS, Pauer GJ, Sturgill-Short GM, Huang J, Maguire MG, Martin DF; Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) Research Group.

JAMA Ophthalmol. 2014 May;132(5):521-7.

PMID:
24652518
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The benefits of using genetic information to design prevention trials.

Hu Y, Li L, Ehm MG, Bing N, Song K, Nelson MR, Talmud PJ, Hingorani AD, Kumari M, Kivimäki M, Xu CF, Waterworth DM, Whittaker JC, Abecasis GR, Spino C, Kang HM.

Am J Hum Genet. 2013 Apr 4;92(4):547-57. doi: 10.1016/j.ajhg.2013.03.003. Epub 2013 Mar 28.

PMID:
23541341
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Phenotype variations affect genetic association studies of degenerative disc disease: conclusions of analysis of genetic association of 58 single nucleotide polymorphisms with highly specific phenotypes for disc degeneration in 332 subjects.

Rajasekaran S, Kanna RM, Senthil N, Raveendran M, Cheung KM, Chan D, Subramaniam S, Shetty AP.

Spine J. 2013 Oct;13(10):1309-20. doi: 10.1016/j.spinee.2013.05.019. Epub 2013 Jun 21.

PMID:
23792102
[PubMed - indexed for MEDLINE]
14.

The medical and economic roles of pipeline pharmacogenetics: Alzheimer's disease as a model of efficacy and HLA-B(*)5701 as a model of safety.

Roses AD.

Neuropsychopharmacology. 2009 Jan;34(1):6-17. doi: 10.1038/npp.2008.153. Epub 2008 Oct 15. Review.

PMID:
18923406
[PubMed - indexed for MEDLINE]
Free Article
15.

Genome-wide association analyses of genetic, phenotypic, and environmental risks in the age-related eye disease study.

Ryu E, Fridley BL, Tosakulwong N, Bailey KR, Edwards AO.

Mol Vis. 2010 Dec 17;16:2811-21.

PMID:
21197116
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Data mining of high density genomic variant data for prediction of Alzheimer's disease risk.

Briones N, Dinu V.

BMC Med Genet. 2012 Jan 25;13:7. doi: 10.1186/1471-2350-13-7.

PMID:
22273362
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Genetic determinants of mortality. Can findings from genome-wide association studies explain variation in human mortality?

Ganna A, Rivadeneira F, Hofman A, Uitterlinden AG, Magnusson PK, Pedersen NL, Ingelsson E, Tiemeier H.

Hum Genet. 2013 May;132(5):553-61. doi: 10.1007/s00439-013-1267-6. Epub 2013 Jan 25.

PMID:
23354976
[PubMed - indexed for MEDLINE]
18.

Trick or treat: the effect of placebo on the power of pharmacogenetic association studies.

Singer C, Grossman I, Avidan N, Beckmann JS, Pe'er I.

Hum Genomics. 2005 Mar;2(1):28-38.

PMID:
15814066
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression.

Ising M, Lucae S, Binder EB, Bettecken T, Uhr M, Ripke S, Kohli MA, Hennings JM, Horstmann S, Kloiber S, Menke A, Bondy B, Rupprecht R, Domschke K, Baune BT, Arolt V, Rush AJ, Holsboer F, Müller-Myhsok B.

Arch Gen Psychiatry. 2009 Sep;66(9):966-75. doi: 10.1001/archgenpsychiatry.2009.95.

PMID:
19736353
[PubMed - indexed for MEDLINE]
20.

Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus.

Tantisira KG, Damask A, Szefler SJ, Schuemann B, Markezich A, Su J, Klanderman B, Sylvia J, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Israel E; SHARP Investigators.

Am J Respir Crit Care Med. 2012 Jun 15;185(12):1286-91. doi: 10.1164/rccm.201111-2061OC. Epub 2012 Apr 26.

PMID:
22538805
[PubMed - indexed for MEDLINE]
Free PMC Article

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