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Results: 1 to 20 of 85

1.

Modulation of cell surface expression of nonactivated cholecystokinin receptors using bivalent ligand-induced internalization.

Harikumar KG, Akgün E, Portoghese PS, Miller LJ.

J Med Chem. 2010 Apr 8;53(7):2836-42. doi: 10.1021/jm100135g.

PMID:
20235611
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Induced association of mu opioid (MOP) and type 2 cholecystokinin (CCK2) receptors by novel bivalent ligands.

Zheng Y, Akgün E, Harikumar KG, Hopson J, Powers MD, Lunzer MM, Miller LJ, Portoghese PS.

J Med Chem. 2009 Jan 22;52(2):247-58. doi: 10.1021/jm800174p.

PMID:
19113864
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Visualization of G protein-coupled receptor trafficking with the aid of the green fluorescent protein. Endocytosis and recycling of cholecystokinin receptor type A.

Tarasova NI, Stauber RH, Choi JK, Hudson EA, Czerwinski G, Miller JL, Pavlakis GN, Michejda CJ, Wank SA.

J Biol Chem. 1997 Jun 6;272(23):14817-24.

PMID:
9169450
[PubMed - indexed for MEDLINE]
Free Article
4.

Ligand-induced internalization of the type 1 cholecystokinin receptor independent of recognized signaling activity.

Cawston EE, Harikumar KG, Miller LJ.

Am J Physiol Cell Physiol. 2012 Feb 1;302(3):C615-27. doi: 10.1152/ajpcell.00193.2011. Epub 2011 Nov 2.

PMID:
22049215
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Effects of cholecystokinin-58 on type 1 cholecystokinin receptor function and regulation.

Wu SV, Harikumar KG, Burgess RJ, Reeve JR Jr, Miller LJ.

Am J Physiol Gastrointest Liver Physiol. 2008 Sep;295(3):G641-7. doi: 10.1152/ajpgi.90390.2008.

PMID:
18776046
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Dual pathways of internalization of the cholecystokinin receptor.

Roettger BF, Rentsch RU, Pinon D, Holicky E, Hadac E, Larkin JM, Miller LJ.

J Cell Biol. 1995 Mar;128(6):1029-41.

PMID:
7896869
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Bivalent ligands that target μ opioid (MOP) and cannabinoid1 (CB1) receptors are potent analgesics devoid of tolerance.

Le Naour M, Akgün E, Yekkirala A, Lunzer MM, Powers MD, Kalyuzhny AE, Portoghese PS.

J Med Chem. 2013 Jul 11;56(13):5505-13. doi: 10.1021/jm4005219. Epub 2013 Jun 20.

PMID:
23734559
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

mu and delta-opioid receptor agonists induce mitogen-activated protein kinase (MAPK) activation in the absence of receptor internalization.

Kramer HK, Simon EJ.

Neuropharmacology. 2000 Jul 24;39(10):1707-19.

PMID:
10884553
[PubMed - indexed for MEDLINE]
9.

Key differences in molecular complexes of the cholecystokinin receptor with structurally related peptide agonist, partial agonist, and antagonist.

Arlander SJ, Dong M, Ding XQ, Pinon DI, Miller LJ.

Mol Pharmacol. 2004 Sep;66(3):545-52.

PMID:
15322246
[PubMed - indexed for MEDLINE]
Free Article
10.
11.

Regulation of lateral mobility and cellular trafficking of the CCK receptor by a partial agonist.

Roettger BF, Pinon DI, Burghardt TP, Miller LJ.

Am J Physiol. 1999 Mar;276(3 Pt 1):C539-47.

PMID:
10069980
[PubMed - indexed for MEDLINE]
Free Article
12.
13.

Cellular handling of unoccupied and agonist-stimulated cholecystokinin receptor determined by immunolocalization.

Fischer de Toledo C, Roettger BF, Morys-Wortmann C, Schmidt WE, Miller LJ.

Am J Physiol. 1997 Mar;272(3 Pt 1):G488-97.

PMID:
9124569
[PubMed - indexed for MEDLINE]
14.

Heterodimerization of type A and B cholecystokinin receptors enhance signaling and promote cell growth.

Cheng ZJ, Harikumar KG, Holicky EL, Miller LJ.

J Biol Chem. 2003 Dec 26;278(52):52972-9. Epub 2003 Oct 8.

PMID:
14534299
[PubMed - indexed for MEDLINE]
Free Article
15.

Monitoring the state of cholecystokinin receptor oligomerization after ligand binding using decay of time-resolved fluorescence anisotropy.

Harikumar KG, Miller LJ.

Ann N Y Acad Sci. 2008 Nov;1144:21-7. doi: 10.1196/annals.1418.004.

PMID:
19076359
[PubMed - indexed for MEDLINE]
Free PMC Article
16.
17.

Internalization and down-regulation of mu opioid receptors by endomorphins and morphine in SH-SY5Y human neuroblastoma cells.

Horner KA, Zadina JE.

Brain Res. 2004 Dec 3;1028(2):121-32.

PMID:
15527737
[PubMed - indexed for MEDLINE]
18.

Opioid agonist and antagonist bivalent ligands. The relationship between spacer length and selectivity at multiple opioid receptors.

Portoghese PS, Larson DL, Sayre LM, Yim CB, Ronsisvalle G, Tam SW, Takemori AE.

J Med Chem. 1986 Oct;29(10):1855-61.

PMID:
3020244
[PubMed - indexed for MEDLINE]
19.

Insulation of a G protein-coupled receptor on the plasmalemmal surface of the pancreatic acinar cell.

Roettger BF, Rentsch RU, Hadac EM, Hellen EH, Burghardt TP, Miller LJ.

J Cell Biol. 1995 Aug;130(3):579-90.

PMID:
7622559
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Protein kinase C-mediated inhibition of transmembrane signalling through CCK(A) and CCK(B) receptors.

Smeets RL, Fouraux MA, van Emst-de Vries SE, De Pont JJ, Willems PH.

Br J Pharmacol. 1998 Mar;123(6):1189-97.

PMID:
9559904
[PubMed - indexed for MEDLINE]
Free PMC Article

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