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Results: 1 to 20 of 93

1.

Antineoplastic effects of decitabine, an inhibitor of DNA promoter methylation, in adrenocortical carcinoma cells.

Suh I, Weng J, Fernandez-Ranvier G, Shen WT, Duh QY, Clark OH, Kebebew E.

Arch Surg. 2010 Mar;145(3):226-32. doi: 10.1001/archsurg.2009.292.

PMID:
20231622
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Candidate diagnostic markers and tumor suppressor genes for adrenocortical carcinoma by expression profile of genes on chromosome 11q13.

Fernandez-Ranvier GG, Weng J, Yeh RF, Shibru D, Khafnashar E, Chung KW, Hwang J, Duh QY, Clark OH, Kebebew E.

World J Surg. 2008 May;32(5):873-81. doi: 10.1007/s00268-008-9521-0.

PMID:
18324346
[PubMed - indexed for MEDLINE]
3.

Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas.

Stewart DJ, Issa JP, Kurzrock R, Nunez MI, Jelinek J, Hong D, Oki Y, Guo Z, Gupta S, Wistuba II.

Clin Cancer Res. 2009 Jun 1;15(11):3881-8. doi: 10.1158/1078-0432.CCR-08-2196. Epub 2009 May 26.

PMID:
19470736
[PubMed - indexed for MEDLINE]
Free Article
4.

Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation.

Samlowski WE, Leachman SA, Wade M, Cassidy P, Porter-Gill P, Busby L, Wheeler R, Boucher K, Fitzpatrick F, Jones DA, Karpf AR.

J Clin Oncol. 2005 Jun 10;23(17):3897-905. Epub 2005 Mar 7. Erratum in: J Clin Oncol. 2006 Apr 10;24(11):1784. Dosage error in published abstract; MEDLINE/PubMed abstract corrected.

PMID:
15753459
[PubMed - indexed for MEDLINE]
Free Article
5.

Transformation-dependent silencing of tumor-selective apoptosis-inducing TRAIL by DNA hypermethylation is antagonized by decitabine.

Lund P, Kotova I, Kedinger V, Khanwalkar H, Voltz E, Hahn WC, Gronemeyer H.

Mol Cancer Ther. 2011 Sep;10(9):1611-23. doi: 10.1158/1535-7163.MCT-11-0140. Epub 2011 Jun 22.

PMID:
21697397
[PubMed - indexed for MEDLINE]
Free Article
6.

Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma.

Rubinstein JC, Tran N, Ma S, Halaban R, Krauthammer M.

BMC Med Genomics. 2010 Feb 9;3:4. doi: 10.1186/1755-8794-3-4.

PMID:
20144234
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

DNA methylation affects cell proliferation, cortisol secretion and steroidogenic gene expression in human adrenocortical NCI-H295R cells.

Liu J, Li XD, Vaheri A, Voutilainen R.

J Mol Endocrinol. 2004 Dec;33(3):651-62.

PMID:
15591025
[PubMed - indexed for MEDLINE]
Free Article
8.

Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies.

Issa JP, Garcia-Manero G, Giles FJ, Mannari R, Thomas D, Faderl S, Bayar E, Lyons J, Rosenfeld CS, Cortes J, Kantarjian HM.

Blood. 2004 Mar 1;103(5):1635-40. Epub 2003 Nov 6.

PMID:
14604977
[PubMed - indexed for MEDLINE]
Free Article
9.

Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition.

Choi SH, Byun HM, Kwan JM, Issa JP, Yang AS.

Br J Haematol. 2007 Sep;138(5):616-23.

PMID:
17686055
[PubMed - indexed for MEDLINE]
10.

Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo.

Steele N, Finn P, Brown R, Plumb JA.

Br J Cancer. 2009 Mar 10;100(5):758-63. doi: 10.1038/sj.bjc.6604932.

PMID:
19259094
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Decitabine--bedside to bench.

Oki Y, Aoki E, Issa JP.

Crit Rev Oncol Hematol. 2007 Feb;61(2):140-52. Epub 2006 Oct 4. Review.

PMID:
17023173
[PubMed - indexed for MEDLINE]
12.

Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline-based chemotherapy and the demethylating agent decitabine.

Ari F, Napieralski R, Ulukaya E, Dere E, Colling C, Honert K, Kr├╝ger A, Kiechle M, Schmitt M.

Cell Biochem Funct. 2011 Dec;29(8):651-9. doi: 10.1002/cbf.1801. Epub 2011 Sep 1.

PMID:
21887697
[PubMed - indexed for MEDLINE]
13.

DNA methylation in haematological malignancies: the role of decitabine.

Hennessy BT, Garcia-Manero G, Kantarjian HM, Giles FJ.

Expert Opin Investig Drugs. 2003 Dec;12(12):1985-93. Review.

PMID:
14640942
[PubMed - indexed for MEDLINE]
14.

Decitabine, independent of apoptosis, exerts its cytotoxic effects on cell growth in melanoma cells.

Liu QY, Chen DW, Xie LP, Zhang RQ, Wang HZ.

Environ Toxicol Pharmacol. 2011 Nov;32(3):423-9. doi: 10.1016/j.etap.2011.08.008. Epub 2011 Sep 3.

PMID:
22004962
[PubMed - indexed for MEDLINE]
15.

Inhibition of DNA methylation increases follistatin expression and secretion in the human adrenocortical cell line NCI-H295R.

Utriainen P, Liu J, Kuulasmaa T, Voutilainen R.

J Endocrinol. 2006 Feb;188(2):305-10.

PMID:
16461556
[PubMed - indexed for MEDLINE]
Free Article
16.

Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway.

Lavelle D, DeSimone J, Hankewych M, Kousnetzova T, Chen YH.

Leuk Res. 2003 Nov;27(11):999-1007.

PMID:
12859993
[PubMed - indexed for MEDLINE]
17.

Decreased expression of retinoblastoma protein-interacting zinc-finger gene 1 in human esophageal squamous cell cancer by DNA methylation.

Dong SW, Cui YT, Zhong RR, Liang DC, Liu YM, Wang YG, He Z, Wang S, Liang SJ, Zhang P.

Clin Lab. 2012;58(1-2):41-51.

PMID:
22372344
[PubMed - indexed for MEDLINE]
18.

Development of a novel cell-based assay system EPISSAY for screening epigenetic drugs and liposome formulated decitabine.

Lim SP, Kumar R, Akkamsetty Y, Wang W, Ho K, Neilsen PM, Walther DJ, Suetani RJ, Prestidge C, Callen DF.

BMC Cancer. 2013 Mar 13;13:113. doi: 10.1186/1471-2407-13-113.

PMID:
23497118
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Effect of histone deacetylase inhibitor LAQ824 on antineoplastic action of 5-Aza-2'-deoxycytidine (decitabine) on human breast carcinoma cells.

Hurtubise A, Momparler RL.

Cancer Chemother Pharmacol. 2006 Nov;58(5):618-25. Epub 2006 Jun 17.

PMID:
16783580
[PubMed - indexed for MEDLINE]
20.

Analysis of genome-wide methylation and gene expression induced by 5-aza-2'-deoxycytidine identifies BCL2L10 as a frequent methylation target in acute myeloid leukemia.

Fabiani E, Leone G, Giachelia M, D'alo' F, Greco M, Criscuolo M, Guidi F, Rutella S, Hohaus S, Voso MT.

Leuk Lymphoma. 2010 Dec;51(12):2275-84. doi: 10.3109/10428194.2010.528093. Epub 2010 Nov 15.

PMID:
21077739
[PubMed - indexed for MEDLINE]

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