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Dally-like core protein and its mammalian homologues mediate stimulatory and inhibitory effects on Hedgehog signal response.

Williams EH, Pappano WN, Saunders AM, Kim MS, Leahy DJ, Beachy PA.

Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5869-74. doi: 10.1073/pnas.1001777107. Epub 2010 Mar 15.


Structure of the protein core of the glypican Dally-like and localization of a region important for hedgehog signaling.

Kim MS, Saunders AM, Hamaoka BY, Beachy PA, Leahy DJ.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13112-7. doi: 10.1073/pnas.1109877108. Epub 2011 Jul 26.


Dual roles of Drosophila glypican Dally-like in Wingless/Wnt signaling and distribution.

Wu Y, Belenkaya TY, Lin X.

Methods Enzymol. 2010;480:33-50. doi: 10.1016/S0076-6879(10)80002-3. Review.


The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development.

Yan D, Wu Y, Yang Y, Belenkaya TY, Tang X, Lin X.

Development. 2010 Jun;137(12):2033-44. doi: 10.1242/dev.045740.


The Drosophila WIF1 homolog Shifted maintains glypican-independent Hedgehog signaling and interacts with the Hedgehog co-receptors Ihog and Boi.

Avanesov A, Blair SS.

Development. 2013 Jan 1;140(1):107-16. doi: 10.1242/dev.078444. Epub 2012 Nov 15.


A translational block to HSPG synthesis permits BMP signaling in the early Drosophila embryo.

Bornemann DJ, Park S, Phin S, Warrior R.

Development. 2008 Mar;135(6):1039-47. doi: 10.1242/dev.017061. Epub 2008 Feb 6.


Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation.

Han C, Belenkaya TY, Khodoun M, Tauchi M, Lin X, Lin X.

Development. 2004 Apr;131(7):1563-75. Epub 2004 Mar 3.


Drosophila glypicans Dally and Dally-like are essential regulators for JAK/STAT signaling and Unpaired distribution in eye development.

Zhang Y, You J, Ren W, Lin X.

Dev Biol. 2013 Mar 1;375(1):23-32. doi: 10.1016/j.ydbio.2012.12.019. Epub 2013 Jan 8.


Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process.

Han C, Belenkaya TY, Wang B, Lin X.

Development. 2004 Feb;131(3):601-11. Epub 2004 Jan 7.


Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and wingless transcytosis.

Gallet A, Staccini-Lavenant L, Thérond PP.

Dev Cell. 2008 May;14(5):712-25. doi: 10.1016/j.devcel.2008.03.001.


The core protein of glypican Dally-like determines its biphasic activity in wingless morphogen signaling.

Yan D, Wu Y, Feng Y, Lin SC, Lin X.

Dev Cell. 2009 Oct;17(4):470-81. doi: 10.1016/j.devcel.2009.09.001.


Lipoprotein-heparan sulfate interactions in the Hh pathway.

Eugster C, Panáková D, Mahmoud A, Eaton S.

Dev Cell. 2007 Jul;13(1):57-71.


The heparan sulfate proteoglycans Dally-like and Syndecan have distinct functions in axon guidance and visual-system assembly in Drosophila.

Rawson JM, Dimitroff B, Johnson KG, Rawson JM, Ge X, Van Vactor D, Selleck SB.

Curr Biol. 2005 May 10;15(9):833-8.


The function of a Drosophila glypican does not depend entirely on heparan sulfate modification.

Kirkpatrick CA, Knox SM, Staatz WD, Fox B, Lercher DM, Selleck SB.

Dev Biol. 2006 Dec 15;300(2):570-82. Epub 2006 Sep 15.


Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity.

Kreuger J, Perez L, Giraldez AJ, Cohen SM.

Dev Cell. 2004 Oct;7(4):503-12.


Glypicans regulate JAK/STAT signaling and distribution of the Unpaired morphogen.

Hayashi Y, Sexton TR, Dejima K, Perry DW, Takemura M, Kobayashi S, Nakato H, Harrison DA.

Development. 2012 Nov;139(22):4162-71. doi: 10.1242/dev.078055.


Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.

Lum L, Yao S, Mozer B, Rovescalli A, Von Kessler D, Nirenberg M, Beachy PA.

Science. 2003 Mar 28;299(5615):2039-45.

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