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Results: 1 to 20 of 104

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1.

Tryptophan probes at the alpha-synuclein and membrane interface.

Pfefferkorn CM, Lee JC.

J Phys Chem B. 2010 Apr 8;114(13):4615-22. doi: 10.1021/jp908092e.

2.

Structural features of membrane-bound glucocerebrosidase and α-synuclein probed by neutron reflectometry and fluorescence spectroscopy.

Yap TL, Jiang Z, Heinrich F, Gruschus JM, Pfefferkorn CM, Barros M, Curtis JE, Sidransky E, Lee JC.

J Biol Chem. 2015 Jan 9;290(2):744-54. doi: 10.1074/jbc.M114.610584. Epub 2014 Nov 26.

PMID:
25429104
3.

Membrane remodeling by α-synuclein and effects on amyloid formation.

Jiang Z, de Messieres M, Lee JC.

J Am Chem Soc. 2013 Oct 30;135(43):15970-3. doi: 10.1021/ja405993r. Epub 2013 Oct 17.

4.

Depth of α-synuclein in a bilayer determined by fluorescence, neutron reflectometry, and computation.

Pfefferkorn CM, Heinrich F, Sodt AJ, Maltsev AS, Pastor RW, Lee JC.

Biophys J. 2012 Feb 8;102(3):613-21. doi: 10.1016/j.bpj.2011.12.051. Epub 2012 Feb 7.

5.

Defective membrane interactions of familial Parkinson's disease mutant A30P alpha-synuclein.

Jo E, Fuller N, Rand RP, St George-Hyslop P, Fraser PE.

J Mol Biol. 2002 Jan 25;315(4):799-807.

PMID:
11812148
6.

Alpha-synuclein structures probed by 5-fluorotryptophan fluorescence and 19F NMR spectroscopy.

Winkler GR, Harkins SB, Lee JC, Gray HB.

J Phys Chem B. 2006 Apr 6;110(13):7058-61.

PMID:
16571022
7.

alpha-Synuclein membrane interactions and lipid specificity.

Jo E, McLaurin J, Yip CM, St George-Hyslop P, Fraser PE.

J Biol Chem. 2000 Nov 3;275(44):34328-34.

8.

Association of alpha-synuclein and mutants with lipid membranes: spin-label ESR and polarized IR.

Ramakrishnan M, Jensen PH, Marsh D.

Biochemistry. 2006 Mar 14;45(10):3386-95.

PMID:
16519533
9.

A study of the regional effects of alpha-synuclein on the organization and stability of phospholipid bilayers.

Madine J, Doig AJ, Middleton DA.

Biochemistry. 2006 May 9;45(18):5783-92.

PMID:
16669622
10.

Membrane bound α-synuclein is fully embedded in the lipid bilayer while segments with higher flexibility remain.

Wietek J, Haralampiev I, Amoussouvi A, Herrmann A, Stöckl M.

FEBS Lett. 2013 Aug 19;587(16):2572-7. doi: 10.1016/j.febslet.2013.06.034. Epub 2013 Jul 3.

11.

The role of tryptophan residues in an integral membrane protein: diacylglycerol kinase.

Clark EH, East JM, Lee AG.

Biochemistry. 2003 Sep 23;42(37):11065-73.

PMID:
12974643
12.

Structural and dynamical insights into the membrane-bound α-synuclein.

Jain N, Bhasne K, Hemaswasthi M, Mukhopadhyay S.

PLoS One. 2013 Dec 20;8(12):e83752. doi: 10.1371/journal.pone.0083752. eCollection 2013.

13.

Probing conformational change of intrinsically disordered α-synuclein to helical structures by distinctive regional interactions with lipid membranes.

Lee SJ, Lee JW, Choi TS, Jin KS, Lee S, Ban C, Kim HI.

Anal Chem. 2014 Feb 4;86(3):1909-16. doi: 10.1021/ac404132g. Epub 2014 Jan 13.

PMID:
24383916
14.

Coordination of copper to the membrane-bound form of α-synuclein.

Dudzik CG, Walter ED, Abrams BS, Jurica MS, Millhauser GL.

Biochemistry. 2013 Jan 8;52(1):53-60. doi: 10.1021/bi301475q. Epub 2012 Dec 26.

15.

α-Synuclein senses lipid packing defects and induces lateral expansion of lipids leading to membrane remodeling.

Ouberai MM, Wang J, Swann MJ, Galvagnion C, Guilliams T, Dobson CM, Welland ME.

J Biol Chem. 2013 Jul 19;288(29):20883-95. doi: 10.1074/jbc.M113.478297. Epub 2013 Jun 5.

16.

Calcium-triggered membrane interaction of the alpha-synuclein acidic tail.

Tamamizu-Kato S, Kosaraju MG, Kato H, Raussens V, Ruysschaert JM, Narayanaswami V.

Biochemistry. 2006 Sep 12;45(36):10947-56.

PMID:
16953580
17.

The association of alpha-synuclein with membranes affects bilayer structure, stability, and fibril formation.

Zhu M, Li J, Fink AL.

J Biol Chem. 2003 Oct 10;278(41):40186-97. Epub 2003 Jul 28.

18.

Formation of a high affinity lipid-binding intermediate during the early aggregation phase of alpha-synuclein.

Smith DP, Tew DJ, Hill AF, Bottomley SP, Masters CL, Barnham KJ, Cappai R.

Biochemistry. 2008 Feb 5;47(5):1425-34. doi: 10.1021/bi701522m. Epub 2008 Jan 8.

PMID:
18179253
19.

Molecular insights into the interaction between alpha-synuclein and docosahexaenoic acid.

De Franceschi G, Frare E, Bubacco L, Mammi S, Fontana A, de Laureto PP.

J Mol Biol. 2009 Nov 20;394(1):94-107. doi: 10.1016/j.jmb.2009.09.008. Epub 2009 Sep 8.

PMID:
19747490
20.

Tryptophan spectroscopy studies and black lipid bilayer analysis indicate that the oligomeric structure of Cry1Ab toxin from Bacillus thuringiensis is the membrane-insertion intermediate.

Rausell C, Muñoz-Garay C, Miranda-CassoLuengo R, Gómez I, Rudiño-Piñera E, Soberón M, Bravo A.

Biochemistry. 2004 Jan 13;43(1):166-74.

PMID:
14705942
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