Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 102

Similar articles for PubMed (Select 20203671)

1.

Directed molecular evolution of DREADDs: a generic approach to creating next-generation RASSLs.

Dong S, Rogan SC, Roth BL.

Nat Protoc. 2010 Mar;5(3):561-73. doi: 10.1038/nprot.2009.239. Epub 2010 Feb 25.

PMID:
20203671
2.

Generation of designer receptors exclusively activated by designer drugs (DREADDs) using directed molecular evolution.

Pei Y, Dong S, Roth BL.

Curr Protoc Neurosci. 2010 Jan;Chapter 4:Unit 4.33. doi: 10.1002/0471142301.ns0433s50.

PMID:
20066658
3.

Engineered GPCRs as tools to modulate signal transduction.

Pei Y, Rogan SC, Yan F, Roth BL.

Physiology (Bethesda). 2008 Dec;23:313-21. doi: 10.1152/physiol.00025.2008. Review.

4.

Engineering GPCR signaling pathways with RASSLs.

Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier JM, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL.

Nat Methods. 2008 Aug;5(8):673-8. doi: 10.1038/nmeth.1232. Review.

5.

G-protein-coupled designer receptors - new chemical-genetic tools for signal transduction research.

Thiel G, Kaufmann A, Rössler OG.

Biol Chem. 2013 Dec;394(12):1615-22. doi: 10.1515/hsz-2013-0164. Review.

PMID:
23893685
6.

Developing chemical genetic approaches to explore G protein-coupled receptor function: validation of the use of a receptor activated solely by synthetic ligand (RASSL).

Alvarez-Curto E, Prihandoko R, Tautermann CS, Zwier JM, Pediani JD, Lohse MJ, Hoffmann C, Tobin AB, Milligan G.

Mol Pharmacol. 2011 Dec;80(6):1033-46. doi: 10.1124/mol.111.074674. Epub 2011 Aug 31.

7.

Engineered G-protein Coupled Receptors are Powerful Tools to Investigate Biological Processes and Behaviors.

Nichols CD, Roth BL.

Front Mol Neurosci. 2009 Oct 23;2:16. doi: 10.3389/neuro.02.016.2009. eCollection 2009.

8.

DREADDs (designer receptors exclusively activated by designer drugs): chemogenetic tools with therapeutic utility.

Urban DJ, Roth BL.

Annu Rev Pharmacol Toxicol. 2015;55:399-417. doi: 10.1146/annurev-pharmtox-010814-124803. Epub 2014 Sep 25.

PMID:
25292433
9.

Yeast system as a screening tool for pharmacological assessment of g protein coupled receptors.

Minic J, Sautel M, Salesse R, Pajot-Augy E.

Curr Med Chem. 2005;12(8):961-9. Review.

PMID:
15853708
10.

Novel designer receptors to probe GPCR signaling and physiology.

Wess J, Nakajima K, Jain S.

Trends Pharmacol Sci. 2013 Jul;34(7):385-92. doi: 10.1016/j.tips.2013.04.006. Epub 2013 Jun 13. Review.

11.

Functional fusions of T4 lysozyme in the third intracellular loop of a G protein-coupled receptor identified by a random screening approach in yeast.

Mathew E, Ding FX, Naider F, Dumont ME.

Protein Eng Des Sel. 2013 Jan;26(1):59-71. doi: 10.1093/protein/gzs070. Epub 2012 Oct 16.

12.

Amplification of agonist stimulation of human G-protein-coupled receptor signaling in yeast.

Fukuda N, Ishii J, Kaishima M, Kondo A.

Anal Biochem. 2011 Oct 15;417(2):182-7. doi: 10.1016/j.ab.2011.06.006. Epub 2011 Jun 13.

PMID:
21726523
13.

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand.

Armbruster BN, Li X, Pausch MH, Herlitze S, Roth BL.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5163-8. Epub 2007 Mar 2.

15.

Creation of GPCR-based chemical sensors by directed evolution in yeast.

Ault AD, Broach JR.

Protein Eng Des Sel. 2006 Jan;19(1):1-8. Epub 2005 Nov 1.

16.

Functional analysis of heterologous GPCR signalling pathways in yeast.

Ladds G, Goddard A, Davey J.

Trends Biotechnol. 2005 Jul;23(7):367-73. Review.

PMID:
15923053
17.
18.

Yeast assays for G protein-coupled receptors.

Dowell SJ, Brown AJ.

Methods Mol Biol. 2009;552:213-29. doi: 10.1007/978-1-60327-317-6_15.

PMID:
19513652
19.

A constitutively active GPCR retains its G protein specificity and the ability to form dimers.

Ladds G, Davis K, Das A, Davey J.

Mol Microbiol. 2005 Jan;55(2):482-97.

PMID:
15659165
20.

The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs.

Chen X, Choo H, Huang XP, Yang X, Stone O, Roth BL, Jin J.

ACS Chem Neurosci. 2015 Mar 18;6(3):476-84. doi: 10.1021/cn500325v. Epub 2015 Jan 27.

PMID:
25587888
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk