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Results: 1 to 20 of 92

1.

3-phosphoinositide-dependent protein kinase-1 regulates proliferation and survival of cancer cells with an activated mitogen-activated protein kinase pathway.

Lu Z, Cox-Hipkin MA, Windsor WT, Boyapati A.

Mol Cancer Res. 2010 Mar;8(3):421-32. doi: 10.1158/1541-7786.MCR-09-0179. Epub 2010 Mar 2.

PMID:
20197379
[PubMed - indexed for MEDLINE]
Free Article
2.

Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1.

Fujita N, Sato S, Ishida A, Tsuruo T.

J Biol Chem. 2002 Mar 22;277(12):10346-53. Epub 2002 Jan 4.

PMID:
11779851
[PubMed - indexed for MEDLINE]
Free Article
3.

Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.

Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.

Eur J Pharmacol. 2007 Jun 1;563(1-3):49-60. Epub 2007 Feb 8.

PMID:
17341418
[PubMed - indexed for MEDLINE]
4.

Involvement of 3-phosphoinositide-dependent protein kinase-1 in the MEK/MAPK signal transduction pathway.

Sato S, Fujita N, Tsuruo T.

J Biol Chem. 2004 Aug 6;279(32):33759-67. Epub 2004 Jun 2.

PMID:
15175348
[PubMed - indexed for MEDLINE]
Free Article
5.

Inhibition of phosphatidylinositol 3-kinase- and ERK MAPK-regulated protein synthesis reveals the pro-apoptotic properties of CD40 ligation in carcinoma cells.

Davies CC, Mason J, Wakelam MJ, Young LS, Eliopoulos AG.

J Biol Chem. 2004 Jan 9;279(2):1010-9. Epub 2003 Oct 27.

PMID:
14581487
[PubMed - indexed for MEDLINE]
Free Article
6.

Mitogen-activated protein kinase pathway-dependent tumor-specific survival signaling in melanoma cells through inactivation of the proapoptotic protein bad.

Eisenmann KM, VanBrocklin MW, Staffend NA, Kitchen SM, Koo HM.

Cancer Res. 2003 Dec 1;63(23):8330-7.

PMID:
14678993
[PubMed - indexed for MEDLINE]
Free Article
7.

Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression.

Liu ZJ, Xiao M, Balint K, Smalley KS, Brafford P, Qiu R, Pinnix CC, Li X, Herlyn M.

Cancer Res. 2006 Apr 15;66(8):4182-90.

PMID:
16618740
[PubMed - indexed for MEDLINE]
Free Article
8.

Transforming growth factor beta induces apoptosis through repressing the phosphoinositide 3-kinase/AKT/survivin pathway in colon cancer cells.

Wang J, Yang L, Yang J, Kuropatwinski K, Wang W, Liu XQ, Hauser J, Brattain MG.

Cancer Res. 2008 May 1;68(9):3152-60. doi: 10.1158/0008-5472.CAN-07-5348.

PMID:
18451140
[PubMed - indexed for MEDLINE]
Free Article
10.

Delineating the mechanism by which selenium deactivates Akt in prostate cancer cells.

Wu Y, Zu K, Warren MA, Wallace PK, Ip C.

Mol Cancer Ther. 2006 Feb;5(2):246-52.

PMID:
16505097
[PubMed - indexed for MEDLINE]
Free Article
11.

Phosphoinositide 3-kinase targeting by the beta galactoside binding protein cytokine negates akt gene expression and leads aggressive breast cancer cells to apoptotic death.

Wells V, Mallucci L.

Breast Cancer Res. 2009;11(1):R2. doi: 10.1186/bcr2217. Epub 2009 Jan 8.

PMID:
19133120
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Regulation of transforming growth factor-beta signaling and PDK1 kinase activity by physical interaction between PDK1 and serine-threonine kinase receptor-associated protein.

Seong HA, Jung H, Choi HS, Kim KT, Ha H.

J Biol Chem. 2005 Dec 30;280(52):42897-908. Epub 2005 Oct 26.

PMID:
16251192
[PubMed - indexed for MEDLINE]
Free Article
13.

Down-regulation of mcl-1 by small interfering RNA sensitizes resistant melanoma cells to fas-mediated apoptosis.

Chetoui N, Sylla K, Gagnon-Houde JV, Alcaide-Loridan C, Charron D, Al-Daccak R, Aoudjit F.

Mol Cancer Res. 2008 Jan;6(1):42-52. doi: 10.1158/1541-7786.MCR-07-0080.

PMID:
18234961
[PubMed - indexed for MEDLINE]
Free Article
14.

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.

McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand FE, Navolanic PM, Terrian DM, Franklin RA, D'Assoro AB, Salisbury JL, Mazzarino MC, Stivala F, Libra M.

Adv Enzyme Regul. 2006;46:249-79. Epub 2006 Jul 18.

PMID:
16854453
[PubMed - indexed for MEDLINE]
15.

Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway.

Qiao M, Shapiro P, Kumar R, Passaniti A.

J Biol Chem. 2004 Oct 8;279(41):42709-18. Epub 2004 Aug 9.

PMID:
15304489
[PubMed - indexed for MEDLINE]
Free Article
16.

Phosphatidylinositol 3-kinase and Ras/mitogen-activated protein kinase signaling pathways are required for the regulation of 5-aminolevulinate synthase gene expression by insulin.

Scassa ME, Guberman AS, Varone CL, Cánepa ET.

Exp Cell Res. 2001 Dec 10;271(2):201-13.

PMID:
11716532
[PubMed - indexed for MEDLINE]
17.

Opposing roles of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase in the cellular response to ionizing radiation in human cervical cancer cells.

Kim MJ, Choi SY, Park IC, Hwang SG, Kim C, Choi YH, Kim H, Lee KH, Lee SJ.

Mol Cancer Res. 2008 Nov;6(11):1718-31. doi: 10.1158/1541-7786.MCR-08-0032.

PMID:
19010820
[PubMed - indexed for MEDLINE]
Free Article
18.

Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts.

Conejo R, Lorenzo M.

J Cell Physiol. 2001 Apr;187(1):96-108.

PMID:
11241354
[PubMed - indexed for MEDLINE]
19.

Potential inhibition of PDK1/Akt signaling by phenothiazines suppresses cancer cell proliferation and survival.

Choi JH, Yang YR, Lee SK, Kim SH, Kim YH, Cha JY, Oh SW, Ha JR, Ryu SH, Suh PG.

Ann N Y Acad Sci. 2008 Sep;1138:393-403. doi: 10.1196/annals.1414.041.

PMID:
18837915
[PubMed - indexed for MEDLINE]
20.

Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival.

Wu W, Pew T, Zou M, Pang D, Conzen SD.

J Biol Chem. 2005 Feb 11;280(6):4117-24. Epub 2004 Dec 7.

PMID:
15590693
[PubMed - indexed for MEDLINE]
Free Article

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