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GDP-bound Galphai2 regulates spinal motor neuron differentiation through interaction with GDE2.

Periz G, Yan Y, Bitzer ZT, Sockanathan S.

Dev Biol. 2010 May 1;341(1):213-21. doi: 10.1016/j.ydbio.2010.02.032. Epub 2010 Mar 1.


Transmembrane protein GDE2 induces motor neuron differentiation in vivo.

Rao M, Sockanathan S.

Science. 2005 Sep 30;309(5744):2212-5.


The antioxidant enzyme Prdx1 controls neuronal differentiation by thiol-redox-dependent activation of GDE2.

Yan Y, Sabharwal P, Rao M, Sockanathan S.

Cell. 2009 Sep 18;138(6):1209-21. doi: 10.1016/j.cell.2009.06.042.


Boundary cap cells constrain spinal motor neuron somal migration at motor exit points by a semaphorin-plexin mechanism.

Bron R, Vermeren M, Kokot N, Andrews W, Little GE, Mitchell KJ, Cohen J.

Neural Dev. 2007 Oct 30;2:21.


GDE2 regulates subtype-specific motor neuron generation through inhibition of Notch signaling.

Sabharwal P, Lee C, Park S, Rao M, Sockanathan S.

Neuron. 2011 Sep 22;71(6):1058-70. doi: 10.1016/j.neuron.2011.07.028. Epub 2011 Sep 21.


Motor neuron columnar fate imposed by sequential phases of Hox-c activity.

Dasen JS, Liu JP, Jessell TM.

Nature. 2003 Oct 30;425(6961):926-33.


Directed differentiation of embryonic stem cells into motor neurons.

Wichterle H, Lieberam I, Porter JA, Jessell TM.

Cell. 2002 Aug 9;110(3):385-97.


Establishment of motor neuron-V3 interneuron progenitor domain boundary in ventral spinal cord requires Groucho-mediated transcriptional corepression.

Todd KJ, Lan-Chow-Wing N, Salin-Cantegrel A, Cotter A, Zagami CJ, Lo R, Stifani S.

PLoS One. 2012;7(2):e31176. doi: 10.1371/journal.pone.0031176. Epub 2012 Feb 17.


Forcing neural progenitor cells to cycle is insufficient to alter cell-fate decision and timing of neuronal differentiation in the spinal cord.

Lobjois V, Bel-Vialar S, Trousse F, Pituello F.

Neural Dev. 2008 Feb 13;3:4. doi: 10.1186/1749-8104-3-4.


Regulation of motor neuron subtype identity by repressor activity of Mnx class homeodomain proteins.

William CM, Tanabe Y, Jessell TM.

Development. 2003 Apr;130(8):1523-36.


Activation of TRPC4β by Gαi subunit increases Ca2+ selectivity and controls neurite morphogenesis in cultured hippocampal neuron.

Jeon JP, Roh SE, Wie J, Kim J, Kim H, Lee KP, Yang D, Jeon JH, Cho NH, Kim IG, Kang DE, Kim HJ, So I.

Cell Calcium. 2013 Oct;54(4):307-19. doi: 10.1016/j.ceca.2013.07.006. Epub 2013 Aug 14.


Jagged2 controls the generation of motor neuron and oligodendrocyte progenitors in the ventral spinal cord.

Rabadán MA, Cayuso J, Le Dréau G, Cruz C, Barzi M, Pons S, Briscoe J, Martí E.

Cell Death Differ. 2012 Feb;19(2):209-19. doi: 10.1038/cdd.2011.84. Epub 2011 Jul 1.


Competition for Gβγ dimers mediates a specific cross-talk between stimulatory and inhibitory G protein α subunits of the adenylyl cyclase in cardiomyocytes.

Hippe HJ, Lüdde M, Schnoes K, Novakovic A, Lutz S, Katus HA, Niroomand F, Nürnberg B, Frey N, Wieland T.

Naunyn Schmiedebergs Arch Pharmacol. 2013 Jun;386(6):459-69. doi: 10.1007/s00210-013-0876-x. Epub 2013 Apr 26.


Gαi2- and Gαi3-deficient mice display opposite severity of myocardial ischemia reperfusion injury.

Köhler D, Devanathan V, Bernardo de Oliveira Franz C, Eldh T, Novakovic A, Roth JM, Granja T, Birnbaumer L, Rosenberger P, Beer-Hammer S, Nürnberg B.

PLoS One. 2014 May 23;9(5):e98325. doi: 10.1371/journal.pone.0098325. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0119092.


Nkx2.2+ progenitors generate somatic motoneurons in the chick spinal cord.

Gotoh H, Ono K, Nomura T, Takebayashi H, Harada H, Nakamura H, Ikenaka K.

PLoS One. 2012;7(12):e51581. doi: 10.1371/journal.pone.0051581. Epub 2012 Dec 17.


GDE2 promotes neurogenesis by glycosylphosphatidylinositol-anchor cleavage of RECK.

Park S, Lee C, Sabharwal P, Zhang M, Meyers CL, Sockanathan S.

Science. 2013 Jan 18;339(6117):324-8. doi: 10.1126/science.1231921.


Requirement of Galphai in thymic homing and early T cell development.

Jin Y, Wu MX.

Mol Immunol. 2008 Jul;45(12):3401-10. doi: 10.1016/j.molimm.2008.04.007. Epub 2008 May 23.


Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification.

Vallstedt A, Muhr J, Pattyn A, Pierani A, Mendelsohn M, Sander M, Jessell TM, Ericson J.

Neuron. 2001 Sep 13;31(5):743-55.

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