Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 162


ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.

Alexander A, Cai SL, Kim J, Nanez A, Sahin M, MacLean KH, Inoki K, Guan KL, Shen J, Person MD, Kusewitt D, Mills GB, Kastan MB, Walker CL.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4153-8. doi: 10.1073/pnas.0913860107. Epub 2010 Feb 16. Erratum in: Proc Natl Acad Sci U S A. 2012 May 22;109(21):8352.


Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1.

Tripathi DN, Chowdhury R, Trudel LJ, Tee AR, Slack RS, Walker CL, Wogan GN.

Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):E2950-7. doi: 10.1073/pnas.1307736110. Epub 2013 Jul 22.


ATM engages the TSC2/mTORC1 signaling node to regulate autophagy.

Alexander A, Kim J, Walker CL.

Autophagy. 2010 Jul;6(5):672-3. doi: 10.4161/auto.6.5.12509. Epub 2010 Jul 1.


Differential localization of ATM is correlated with activation of distinct downstream signaling pathways.

Alexander A, Walker CL.

Cell Cycle. 2010 Sep 15;9(18):3685-6. Epub 2010 Sep 5.


ATM localization and gene expression in the adult mouse eye.

Leemput J, Masson C, Bigot K, Errachid A, Dansault A, Provost A, Gadin S, Aoufouchi S, Menasche M, Abitbol M.

Mol Vis. 2009;15:393-416. Epub 2009 Feb 20.


mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α.

Cam H, Easton JB, High A, Houghton PJ.

Mol Cell. 2010 Nov 24;40(4):509-20. doi: 10.1016/j.molcel.2010.10.030.


Activation of AMP-activated protein kinase in cerebella of Atm-/- mice is attributable to accumulation of reactive oxygen species.

Kuang X, Yan M, Ajmo JM, Scofield VL, Stoica G, Wong PK.

Biochem Biophys Res Commun. 2012 Feb 10;418(2):267-72. doi: 10.1016/j.bbrc.2012.01.008. Epub 2012 Jan 10.


The ATM protein kinase and cellular redox signaling: beyond the DNA damage response.

Ditch S, Paull TT.

Trends Biochem Sci. 2012 Jan;37(1):15-22. doi: 10.1016/j.tibs.2011.10.002. Epub 2011 Nov 11. Review.


Promotion of DNA repair by nuclear IKKβ phosphorylation of ATM in response to genotoxic stimuli.

Sakamoto K, Hikiba Y, Nakagawa H, Hirata Y, Hayakawa Y, Kinoshita H, Nakata W, Sakitani K, Takahashi R, Akanuma M, Kamata H, Maeda S.

Oncogene. 2013 Apr 4;32(14):1854-62. doi: 10.1038/onc.2012.192. Epub 2012 May 21.


Inactivation of ataxia telangiectasia mutated gene can increase intracellular reactive oxygen species levels and alter radiation-induced cell death pathways in human glioma cells.

Wang SC, Wu CC, Wei YY, Hong JH, Chiang CS.

Int J Radiat Biol. 2011 Apr;87(4):432-42. doi: 10.3109/09553002.2011.538128. Epub 2011 Jan 4.


The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice.

Mercer JR, Yu E, Figg N, Cheng KK, Prime TA, Griffin JL, Masoodi M, Vidal-Puig A, Murphy MP, Bennett MR.

Free Radic Biol Med. 2012 Mar 1;52(5):841-9. doi: 10.1016/j.freeradbiomed.2011.11.026. Epub 2011 Dec 14.


Ataxia telangiectasia mutated (ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cell senescence.

Zhan H, Suzuki T, Aizawa K, Miyagawa K, Nagai R.

J Biol Chem. 2010 Sep 17;285(38):29662-70. doi: 10.1074/jbc.M110.125138. Epub 2010 Jul 16.


Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death.

Tian B, Yang Q, Mao Z.

Nat Cell Biol. 2009 Feb;11(2):211-8. doi: 10.1038/ncb1829. Epub 2009 Jan 18. Erratum in: Nat Cell Biol. 2009 Aug;11(8);1042.


Bortezomib induces G2-M arrest in human colon cancer cells through ROS-inducible phosphorylation of ATM-CHK1.

Hong YS, Hong SW, Kim SM, Jin DH, Shin JS, Yoon DH, Kim KP, Lee JL, Heo DS, Lee JS, Kim TW.

Int J Oncol. 2012 Jul;41(1):76-82. doi: 10.3892/ijo.2012.1448. Epub 2012 Apr 26.


Lycopene inhibits Helicobacter pylori-induced ATM/ATR-dependent DNA damage response in gastric epithelial AGS cells.

Jang SH, Lim JW, Morio T, Kim H.

Free Radic Biol Med. 2012 Feb 1;52(3):607-15. doi: 10.1016/j.freeradbiomed.2011.11.010. Epub 2011 Nov 20.


New insights into the roles of ATM and DNA-PKcs in the cellular response to oxidative stress.

Chen BP, Li M, Asaithamby A.

Cancer Lett. 2012 Dec 31;327(1-2):103-10. doi: 10.1016/j.canlet.2011.12.004. Epub 2011 Dec 9. Review.


The ATM-dependent DNA damage signaling pathway.

Kitagawa R, Kastan MB.

Cold Spring Harb Symp Quant Biol. 2005;70:99-109. Review.


Ataxia telangiectasia mutated impacts insulin-like growth factor 1 signalling in skeletal muscle.

Ching JK, Luebbert SH, Collins RL 4th, Zhang Z, Marupudi N, Banerjee S, Hurd RD, Ralston L, Fisher JS.

Exp Physiol. 2013 Feb;98(2):526-35. doi: 10.1113/expphysiol.2012.066357. Epub 2012 Aug 31.


The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain.

Kanu N, Penicud K, Hristova M, Wong B, Irvine E, Plattner F, Raivich G, Behrens A.

J Biol Chem. 2010 Dec 3;285(49):38534-42. doi: 10.1074/jbc.M110.145896. Epub 2010 Oct 2.


Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.

Huang X, Wullschleger S, Shpiro N, McGuire VA, Sakamoto K, Woods YL, McBurnie W, Fleming S, Alessi DR.

Biochem J. 2008 Jun 1;412(2):211-21. doi: 10.1042/BJ20080557.

Items per page

Supplemental Content

Write to the Help Desk