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Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded.

Yu J, Zheng Y, Dong J, Klusza S, Deng WM, Pan D.

Dev Cell. 2010 Feb 16;18(2):288-99. doi: 10.1016/j.devcel.2009.12.012.


The WW domain protein Kibra acts upstream of Hippo in Drosophila.

Baumgartner R, Poernbacher I, Buser N, Hafen E, Stocker H.

Dev Cell. 2010 Feb 16;18(2):309-16. doi: 10.1016/j.devcel.2009.12.013.


Kibra is a regulator of the Salvador/Warts/Hippo signaling network.

Genevet A, Wehr MC, Brain R, Thompson BJ, Tapon N.

Dev Cell. 2010 Feb 16;18(2):300-8. doi: 10.1016/j.devcel.2009.12.011.


The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth.

Hamaratoglu F, Gajewski K, Sansores-Garcia L, Morrison C, Tao C, Halder G.

J Cell Sci. 2009 Jul 15;122(Pt 14):2351-9. doi: 10.1242/jcs.046482. Epub 2009 Jun 16.


The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded.

Ling C, Zheng Y, Yin F, Yu J, Huang J, Hong Y, Wu S, Pan D.

Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10532-7. doi: 10.1073/pnas.1004279107. Epub 2010 May 24.


Ajuba LIM proteins are negative regulators of the Hippo signaling pathway.

Das Thakur M, Feng Y, Jagannathan R, Seppa MJ, Skeath JB, Longmore GD.

Curr Biol. 2010 Apr 13;20(7):657-62. doi: 10.1016/j.cub.2010.02.035. Epub 2010 Mar 18.


The Hippo pathway and apico-basal cell polarity.

Genevet A, Tapon N.

Biochem J. 2011 Jun 1;436(2):213-24. doi: 10.1042/BJ20110217. Review.


The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control.

Zhang L, Ren F, Zhang Q, Chen Y, Wang B, Jiang J.

Dev Cell. 2008 Mar;14(3):377-87. doi: 10.1016/j.devcel.2008.01.006. Epub 2008 Feb 7.


The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway.

Wu S, Liu Y, Zheng Y, Dong J, Pan D.

Dev Cell. 2008 Mar;14(3):388-98. doi: 10.1016/j.devcel.2008.01.007. Epub 2008 Feb 7.


The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie.

Badouel C, Gardano L, Amin N, Garg A, Rosenfeld R, Le Bihan T, McNeill H.

Dev Cell. 2009 Mar;16(3):411-20. doi: 10.1016/j.devcel.2009.01.010.


The cell adhesion molecule echinoid functions as a tumor suppressor and upstream regulator of the Hippo signaling pathway.

Yue T, Tian A, Jiang J.

Dev Cell. 2012 Feb 14;22(2):255-67. doi: 10.1016/j.devcel.2011.12.011. Epub 2012 Jan 25.


The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.

Willecke M, Hamaratoglu F, Kango-Singh M, Udan R, Chen CL, Tao C, Zhang X, Halder G.

Curr Biol. 2006 Nov 7;16(21):2090-100. Epub 2006 Sep 21.


Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded.

Robinson BS, Huang J, Hong Y, Moberg KH.

Curr Biol. 2010 Apr 13;20(7):582-90. doi: 10.1016/j.cub.2010.03.019. Epub 2010 Apr 1.


Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.

Zhao B, Wei X, Li W, Udan RS, Yang Q, Kim J, Xie J, Ikenoue T, Yu J, Li L, Zheng P, Ye K, Chinnaiyan A, Halder G, Lai ZC, Guan KL.

Genes Dev. 2007 Nov 1;21(21):2747-61.


Differential requirement of Salvador-Warts-Hippo pathway members for organ size control in Drosophila melanogaster.

Milton CC, Zhang X, Albanese NO, Harvey KF.

Development. 2010 Mar;137(5):735-43. doi: 10.1242/dev.042309. Epub 2010 Jan 28.


Salvador-warts-hippo signaling promotes Drosophila posterior follicle cell maturation downstream of notch.

Polesello C, Tapon N.

Curr Biol. 2007 Nov 6;17(21):1864-70. Epub 2007 Oct 25. Erratum in: Curr Biol. 2007 Nov 20;17(22):2001.


The Drosophila RASSF homolog antagonizes the hippo pathway.

Polesello C, Huelsmann S, Brown NH, Tapon N.

Curr Biol. 2006 Dec 19;16(24):2459-65.


Inactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulation.

Sekido Y.

Pathol Int. 2011 Jun;61(6):331-44. doi: 10.1111/j.1440-1827.2011.02666.x. Epub 2011 May 2. Review.


Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms.

Grzeschik NA, Parsons LM, Allott ML, Harvey KF, Richardson HE.

Curr Biol. 2010 Apr 13;20(7):573-81. doi: 10.1016/j.cub.2010.01.055. Epub 2010 Apr 1.


Homeodomain-interacting protein kinase regulates Yorkie activity to promote tissue growth.

Chen J, Verheyen EM.

Curr Biol. 2012 Sep 11;22(17):1582-6. doi: 10.1016/j.cub.2012.06.074. Epub 2012 Jul 26.

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