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Results: 1 to 20 of 1075

1.

Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma.

Rubinstein JC, Tran N, Ma S, Halaban R, Krauthammer M.

BMC Med Genomics. 2010 Feb 9;3:4. doi: 10.1186/1755-8794-3-4.

PMID:
20144234
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists.

Mossman D, Kim KT, Scott RJ.

BMC Cancer. 2010 Jul 12;10:366. doi: 10.1186/1471-2407-10-366.

PMID:
20618997
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Promoter methylation of MGMT, MLH1 and RASSF1A tumor suppressor genes in head and neck squamous cell carcinoma: pharmacological genome demethylation reduces proliferation of head and neck squamous carcinoma cells.

Koutsimpelas D, Pongsapich W, Heinrich U, Mann S, Mann WJ, Brieger J.

Oncol Rep. 2012 Apr;27(4):1135-41. doi: 10.3892/or.2012.1624. Epub 2012 Jan 9.

PMID:
22246327
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

NGX6 gene mediated by promoter methylation as a potential molecular marker in colorectal cancer.

Liu M, Peng Y, Wang X, Guo Q, Shen S, Li G.

BMC Cancer. 2010 Apr 27;10:160. doi: 10.1186/1471-2407-10-160.

PMID:
20423473
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors.

Neumann O, Kesselmeier M, Geffers R, Pellegrino R, Radlwimmer B, Hoffmann K, Ehemann V, Schemmer P, Schirmacher P, Lorenzo Bermejo J, Longerich T.

Hepatology. 2012 Nov;56(5):1817-27. doi: 10.1002/hep.25870. Epub 2012 Oct 14.

PMID:
22689435
[PubMed - indexed for MEDLINE]
6.

Gemcitabine reactivates epigenetically silenced genes and functions as a DNA methyltransferase inhibitor.

Gray SG, Baird AM, O'Kelly F, Nikolaidis G, Almgren M, Meunier A, Dockry E, Hollywood D, Ekström TJ, Perry AS, O'Byrne KJ.

Int J Mol Med. 2012 Dec;30(6):1505-11. doi: 10.3892/ijmm.2012.1138. Epub 2012 Sep 21.

PMID:
23007409
[PubMed - indexed for MEDLINE]
7.

Identification of GPX3 epigenetically silenced by CpG methylation in human esophageal squamous cell carcinoma.

He Y, Wang Y, Li P, Zhu S, Wang J, Zhang S.

Dig Dis Sci. 2011 Mar;56(3):681-8. doi: 10.1007/s10620-010-1369-0. Epub 2010 Aug 20.

PMID:
20725785
[PubMed - indexed for MEDLINE]
8.

Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters.

Shen L, Kondo Y, Guo Y, Zhang J, Zhang L, Ahmed S, Shu J, Chen X, Waterland RA, Issa JP.

PLoS Genet. 2007 Oct;3(10):2023-36. Epub 2007 Sep 10.

PMID:
17967063
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer.

Fujikane T, Nishikawa N, Toyota M, Suzuki H, Nojima M, Maruyama R, Ashida M, Ohe-Toyota M, Kai M, Nishidate T, Sasaki Y, Ohmura T, Hirata K, Tokino T.

Breast Cancer Res Treat. 2010 Aug;122(3):699-710. doi: 10.1007/s10549-009-0600-1. Epub 2009 Oct 27.

PMID:
19859801
[PubMed - indexed for MEDLINE]
10.

Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells.

Heller G, Schmidt WM, Ziegler B, Holzer S, Müllauer L, Bilban M, Zielinski CC, Drach J, Zöchbauer-Müller S.

Cancer Res. 2008 Jan 1;68(1):44-54. doi: 10.1158/0008-5472.CAN-07-2531.

PMID:
18172295
[PubMed - indexed for MEDLINE]
Free Article
11.

Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation.

Samlowski WE, Leachman SA, Wade M, Cassidy P, Porter-Gill P, Busby L, Wheeler R, Boucher K, Fitzpatrick F, Jones DA, Karpf AR.

J Clin Oncol. 2005 Jun 10;23(17):3897-905. Epub 2005 Mar 7. Erratum in: J Clin Oncol. 2006 Apr 10;24(11):1784. Dosage error in published abstract; MEDLINE/PubMed abstract corrected.

PMID:
15753459
[PubMed - indexed for MEDLINE]
Free Article
12.

A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies.

Shames DS, Girard L, Gao B, Sato M, Lewis CM, Shivapurkar N, Jiang A, Perou CM, Kim YH, Pollack JR, Fong KM, Lam CL, Wong M, Shyr Y, Nanda R, Olopade OI, Gerald W, Euhus DM, Shay JW, Gazdar AF, Minna JD.

PLoS Med. 2006 Dec;3(12):e486.

PMID:
17194187
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation.

Zhang YW, Staal B, Dykema KJ, Furge KA, Vande Woude GF.

PLoS One. 2012;7(6):e38955. doi: 10.1371/journal.pone.0038955. Epub 2012 Jun 12.

PMID:
22701735
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo.

Alcazar O, Achberger S, Aldrich W, Hu Z, Negrotto S, Saunthararajah Y, Triozzi P.

Int J Cancer. 2012 Jul 1;131(1):18-29. doi: 10.1002/ijc.26320. Epub 2011 Sep 6.

PMID:
21796622
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer.

Ogishima T, Shiina H, Breault JE, Tabatabai L, Bassett WW, Enokida H, Li LC, Kawakami T, Urakami S, Ribeiro-Filho LA, Terashima M, Fujime M, Igawa M, Dahiya R.

Clin Cancer Res. 2005 Feb 1;11(3):1028-36.

PMID:
15709168
[PubMed - indexed for MEDLINE]
Free Article
16.

Hypermethylation of the p16 (Ink4a) promoter in B6C3F1 mouse primary lung adenocarcinomas and mouse lung cell lines.

Patel AC, Anna CH, Foley JF, Stockton PS, Tyson FL, Barrett JC, Devereux TR.

Carcinogenesis. 2000 Sep;21(9):1691-700.

PMID:
10964101
[PubMed - indexed for MEDLINE]
Free Article
17.

Genome-wide methylation profiling in decitabine-treated patients with acute myeloid leukemia.

Yan P, Frankhouser D, Murphy M, Tam HH, Rodriguez B, Curfman J, Trimarchi M, Geyer S, Wu YZ, Whitman SP, Metzeler K, Walker A, Klisovic R, Jacob S, Grever MR, Byrd JC, Bloomfield CD, Garzon R, Blum W, Caligiuri MA, Bundschuh R, Marcucci G.

Blood. 2012 Sep 20;120(12):2466-74. Epub 2012 Jul 11.

PMID:
22786882
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Analysis of genome-wide methylation and gene expression induced by 5-aza-2'-deoxycytidine identifies BCL2L10 as a frequent methylation target in acute myeloid leukemia.

Fabiani E, Leone G, Giachelia M, D'alo' F, Greco M, Criscuolo M, Guidi F, Rutella S, Hohaus S, Voso MT.

Leuk Lymphoma. 2010 Dec;51(12):2275-84. doi: 10.3109/10428194.2010.528093. Epub 2010 Nov 15.

PMID:
21077739
[PubMed - indexed for MEDLINE]
19.

The depletion of DNA methyltransferase-1 and the epigenetic effects of 5-aza-2'deoxycytidine (decitabine) are differentially regulated by cell cycle progression.

Al-Salihi M, Yu M, Burnett DM, Alexander A, Samlowski WE, Fitzpatrick FA.

Epigenetics. 2011 Aug;6(8):1021-8. doi: 10.4161/epi.6.8.16064. Epub 2011 Aug 1.

PMID:
21725200
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2'-deoxycytidine.

Chen J, Röcken C, Klein-Hitpass L, Götze T, Leodolter A, Malfertheiner P, Ebert MP.

Clin Exp Metastasis. 2004;21(5):389-97.

PMID:
15672863
[PubMed - indexed for MEDLINE]

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