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Results: 1 to 20 of 133

1.

Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine.

Buzza MS, Netzel-Arnett S, Shea-Donohue T, Zhao A, Lin CY, List K, Szabo R, Fasano A, Bugge TH, Antalis TM.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4200-5. doi: 10.1073/pnas.0903923107. Epub 2010 Feb 8.

PMID:
20142489
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Prostasin is required for matriptase activation in intestinal epithelial cells to regulate closure of the paracellular pathway.

Buzza MS, Martin EW, Driesbaugh KH, Désilets A, Leduc R, Antalis TM.

J Biol Chem. 2013 Apr 12;288(15):10328-37. doi: 10.1074/jbc.M112.443432. Epub 2013 Feb 26.

PMID:
23443662
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Protein kinase D promotes airway epithelial barrier dysfunction and permeability through down-regulation of claudin-1.

Gan H, Wang G, Hao Q, Wang QJ, Tang H.

J Biol Chem. 2013 Dec 27;288(52):37343-54. doi: 10.1074/jbc.M113.511527. Epub 2013 Nov 21. Erratum in: J Biol Chem. 2014 Jul 25;289(30):20489.

PMID:
24265314
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Numb modulates the paracellular permeability of intestinal epithelial cells through regulating apical junctional complex assembly and myosin light chain phosphorylation.

Yang Y, Chen L, Tian Y, Ye J, Liu Y, Song L, Pan Q, He Y, Chen W, Peng Z, Wang R.

Exp Cell Res. 2013 Dec 10;319(20):3214-25. doi: 10.1016/j.yexcr.2013.07.003. Epub 2013 Jul 19.

PMID:
23872314
[PubMed - indexed for MEDLINE]
5.

Matriptase protects against experimental colitis and promotes intestinal barrier recovery.

Netzel-Arnett S, Buzza MS, Shea-Donohue T, Désilets A, Leduc R, Fasano A, Bugge TH, Antalis TM.

Inflamm Bowel Dis. 2012 Jul;18(7):1303-14. doi: 10.1002/ibd.21930. Epub 2011 Nov 13.

PMID:
22081509
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Serine proteases decrease intestinal epithelial ion permeability by activation of protein kinase Czeta.

Swystun VA, Renaux B, Moreau F, Wen S, Peplowski MA, Hollenberg MD, MacNaughton WK.

Am J Physiol Gastrointest Liver Physiol. 2009 Jul;297(1):G60-70. doi: 10.1152/ajpgi.00096.2009. Epub 2009 May 21.

PMID:
19460843
[PubMed - indexed for MEDLINE]
Free Article
7.

theta Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: a novel mechanism for regulation of permeability.

Banan A, Zhang LJ, Shaikh M, Fields JZ, Choudhary S, Forsyth CB, Farhadi A, Keshavarzian A.

J Pharmacol Exp Ther. 2005 Jun;313(3):962-82.

PMID:
15900076
[PubMed - indexed for MEDLINE]
Free Article
8.

Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers.

Peng L, Li ZR, Green RS, Holzman IR, Lin J.

J Nutr. 2009 Sep;139(9):1619-25. doi: 10.3945/jn.109.104638. Epub 2009 Jul 22.

PMID:
19625695
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Epithelial integrity is maintained by a matriptase-dependent proteolytic pathway.

List K, Kosa P, Szabo R, Bey AL, Wang CB, Molinolo A, Bugge TH.

Am J Pathol. 2009 Oct;175(4):1453-63. doi: 10.2353/ajpath.2009.090240. Epub 2009 Aug 28.

PMID:
19717635
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Abrogation of IFN-gamma mediated epithelial barrier disruption by serine protease inhibition.

Willemsen LE, Hoetjes JP, van Deventer SJ, van Tol EA.

Clin Exp Immunol. 2005 Nov;142(2):275-84.

PMID:
16232214
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Fucoidan enhances intestinal barrier function by upregulating the expression of claudin-1.

Iraha A, Chinen H, Hokama A, Yonashiro T, Kinjo T, Kishimoto K, Nakamoto M, Hirata T, Kinjo N, Higa F, Tateyama M, Kinjo F, Fujita J.

World J Gastroenterol. 2013 Sep 7;19(33):5500-7. doi: 10.3748/wjg.v19.i33.5500.

PMID:
24023493
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

GLP-2 enhances barrier formation and attenuates TNFα-induced changes in a Caco-2 cell model of the intestinal barrier.

Moran GW, O'Neill C, McLaughlin JT.

Regul Pept. 2012 Oct 10;178(1-3):95-101. doi: 10.1016/j.regpep.2012.07.002. Epub 2012 Jul 15.

PMID:
22809889
[PubMed - indexed for MEDLINE]
13.

Claudins regulate the intestinal barrier in response to immune mediators.

Kinugasa T, Sakaguchi T, Gu X, Reinecker HC.

Gastroenterology. 2000 Jun;118(6):1001-11.

PMID:
10833473
[PubMed - indexed for MEDLINE]
14.

Interleukin-18 facilitates neutrophil transmigration via myosin light chain kinase-dependent disruption of occludin, without altering epithelial permeability.

Lapointe TK, Buret AG.

Am J Physiol Gastrointest Liver Physiol. 2012 Feb 1;302(3):G343-51. doi: 10.1152/ajpgi.00202.2011. Epub 2011 Dec 1.

PMID:
22135309
[PubMed - indexed for MEDLINE]
Free Article
15.

Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice.

Szabo R, Hobson JP, Christoph K, Kosa P, List K, Bugge TH.

Development. 2009 Aug;136(15):2653-63. doi: 10.1242/dev.038430.

PMID:
19592578
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier.

Al-Sadi R, Khatib K, Guo S, Ye D, Youssef M, Ma T.

Am J Physiol Gastrointest Liver Physiol. 2011 Jun;300(6):G1054-64. doi: 10.1152/ajpgi.00055.2011. Epub 2011 Mar 17.

PMID:
21415414
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Activation of the epithelial-to-mesenchymal transition factor snail mediates acetaldehyde-induced intestinal epithelial barrier disruption.

Elamin E, Masclee A, Troost F, Dekker J, Jonkers D.

Alcohol Clin Exp Res. 2014 Feb;38(2):344-53. doi: 10.1111/acer.12234. Epub 2013 Aug 19.

PMID:
24033729
[PubMed - indexed for MEDLINE]
18.

Human ENS regulates the intestinal epithelial barrier permeability and a tight junction-associated protein ZO-1 via VIPergic pathways.

Neunlist M, Toumi F, Oreschkova T, Denis M, Leborgne J, Laboisse CL, Galmiche JP, Jarry A.

Am J Physiol Gastrointest Liver Physiol. 2003 Nov;285(5):G1028-36. Epub 2003 Jul 24.

PMID:
12881224
[PubMed - indexed for MEDLINE]
Free Article
19.

Chymase-mediated intestinal epithelial permeability is regulated by a protease-activating receptor/matrix metalloproteinase-2-dependent mechanism.

Groschwitz KR, Wu D, Osterfeld H, Ahrens R, Hogan SP.

Am J Physiol Gastrointest Liver Physiol. 2013 Mar 1;304(5):G479-89. doi: 10.1152/ajpgi.00186.2012. Epub 2013 Jan 10.

PMID:
23306080
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Role of snail activation in alcohol-induced iNOS-mediated disruption of intestinal epithelial cell permeability.

Forsyth CB, Tang Y, Shaikh M, Zhang L, Keshavarzian A.

Alcohol Clin Exp Res. 2011 Sep;35(9):1635-43. doi: 10.1111/j.1530-0277.2011.01510.x. Epub 2011 Apr 27.

PMID:
21535025
[PubMed - indexed for MEDLINE]
Free PMC Article
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