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Results: 1 to 20 of 99

1.

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef.

Garcia JV, Miller AD.

Nature. 1991 Apr 11;350(6318):508-11.

PMID:
2014052
[PubMed - indexed for MEDLINE]
2.

Specific suppression of human CD4 surface expression by Nef from the pathogenic simian immunodeficiency virus SIVmac239open.

Foster JL, Anderson SJ, Frazier AL, Garcia JV.

Virology. 1994 Jun;201(2):373-9.

PMID:
8184546
[PubMed - indexed for MEDLINE]
3.
5.

Nef from primary isolates of human immunodeficiency virus type 1 suppresses surface CD4 expression in human and mouse T cells.

Anderson S, Shugars DC, Swanstrom R, Garcia JV.

J Virol. 1993 Aug;67(8):4923-31.

PMID:
8331733
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

T cells chronically infected with HIV do not contain sufficient Nef to promote CD4 downmodulation in the absence of envelope-mediated effects.

Cucchiarini M, Barcellini-Couget S, Lefebvre JC, Doglio A.

J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Feb 1;17(2):112-9.

PMID:
9473011
[PubMed - indexed for MEDLINE]
7.

CD4 phosphorylation partially reverses Nef down-regulation of CD4.

Jin YJ, Zhang X, Boursiquot JG, Burakoff SJ.

J Immunol. 2004 Nov 1;173(9):5495-500.

PMID:
15494497
[PubMed - indexed for MEDLINE]
Free Article
8.

Modulation of specific surface receptors and activation sensitization in primary resting CD4+ T lymphocytes by the Nef protein of HIV-1.

Keppler OT, Tibroni N, Venzke S, Rauch S, Fackler OT.

J Leukoc Biol. 2006 Mar;79(3):616-27. Epub 2005 Dec 19.

PMID:
16365153
[PubMed - indexed for MEDLINE]
Free Article
9.

Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection.

Benson RE, Sanfridson A, Ottinger JS, Doyle C, Cullen BR.

J Exp Med. 1993 Jun 1;177(6):1561-6.

PMID:
8098729
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

HIV-1 Nef protein downregulation of CD4 surface expression: relevance of the lck binding domain of CD4.

Bandres JC, Shaw AS, Ratner L.

Virology. 1995 Feb 20;207(1):338-41.

PMID:
7871751
[PubMed - indexed for MEDLINE]
Free Article
11.

HIV-1 Nef mutations abrogating downregulation of CD4 affect other Nef functions and show reduced pathogenicity in transgenic mice.

Hanna Z, Priceputu E, Hu C, Vincent P, Jolicoeur P.

Virology. 2006 Mar 1;346(1):40-52. Epub 2005 Nov 28.

PMID:
16310238
[PubMed - indexed for MEDLINE]
Free Article
12.

HIV- I Nef severely impairs thymocyte development and peripheral T-cell function by a CD4-independent mechanism.

Pennington DJ, Jenkins SA, Brady HJ, Miles CG, Dzierzak EA, Abraham DJ.

Genes Funct. 1997 Dec;1(5-6):321-35.

PMID:
17366702
[PubMed - indexed for MEDLINE]
13.

Inhibition of Nef- and phorbol ester-induced CD4 degradation by macrolide antibiotics.

Luo T, Anderson SJ, Garcia JV.

J Virol. 1996 Mar;70(3):1527-34.

PMID:
8627671
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Activation pathways and human immunodeficiency virus type 1 replication are not altered in CD4+ T cells expressing the nef protein.

Schwartz O, Arenzana-Seisdedos F, Heard JM, Danos O.

AIDS Res Hum Retroviruses. 1992 May;8(5):545-51.

PMID:
1355346
[PubMed - indexed for MEDLINE]
15.

Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein.

Ross TM, Oran AE, Cullen BR.

Curr Biol. 1999 Jun 17;9(12):613-21.

PMID:
10375525
[PubMed - indexed for MEDLINE]
Free Article
16.
17.

CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms.

Rose JJ, Janvier K, Chandrasekhar S, Sekaly RP, Bonifacino JS, Venkatesan S.

J Biol Chem. 2005 Mar 4;280(9):7413-26. Epub 2004 Dec 16.

PMID:
15611114
[PubMed - indexed for MEDLINE]
Free Article
18.

HIV-1 Nef activity in murine T cells. CD4 modulation and positive enhancement.

Rhee SS, Marsh JW.

J Immunol. 1994 May 15;152(10):5128-34.

PMID:
8176229
[PubMed - indexed for MEDLINE]
19.

Induction by human immunodeficiency viruses types 1 and 2 of degradation of CD4 but not of a CD4 mutant unable to bind viral envelope glycoproteins.

Cucchiarini M, Cagnon L, Giordanengo V, Doglio A, Lefebvre JC.

J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Apr 15;8(5):427-36.

PMID:
7697438
[PubMed - indexed for MEDLINE]
20.

Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling.

Iafrate AJ, Bronson S, Skowronski J.

EMBO J. 1997 Feb 17;16(4):673-84.

PMID:
9049297
[PubMed - indexed for MEDLINE]
Free PMC Article

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