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Overexpression of cyclooxygenase-2 in rat oral cancers and prevention of oral carcinogenesis in rats by selective and nonselective COX inhibitors.

McCormick DL, Phillips JM, Horn TL, Johnson WD, Steele VE, Lubet RA.

Cancer Prev Res (Phila). 2010 Jan;3(1):73-81. doi: 10.1158/1940-6207.CAPR-09-0151.


Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib.

Li N, Sood S, Wang S, Fang M, Wang P, Sun Z, Yang CS, Chen X.

Clin Cancer Res. 2005 Mar 1;11(5):2089-96.


Dietary zinc modulation of COX-2 expression and lingual and esophageal carcinogenesis in rats.

Fong LY, Zhang L, Jiang Y, Farber JL.

J Natl Cancer Inst. 2005 Jan 5;97(1):40-50.


Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis.

Reddy BS, Hirose Y, Lubet R, Steele V, Kelloff G, Paulson S, Seibert K, Rao CV.

Cancer Res. 2000 Jan 15;60(2):293-7.


Increased expression of cyclooxygenase-2 protein in 4-nitroquinoline-1-oxide-induced rat tongue carcinomas and chemopreventive efficacy of a specific inhibitor, nimesulide.

Shiotani H, Denda A, Yamamoto K, Kitayama W, Endoh T, Sasaki Y, Tsutsumi N, Sugimura M, Konishi Y.

Cancer Res. 2001 Feb 15;61(4):1451-6.


A COX-2 inhibitor, nimesulide, inhibits chemically-induced rat tongue carcinogenesis through suppression of cell proliferation activity and COX-2 and iNOS expression.

Yoshida K, Tanaka T, Kohno H, Sakata K, Kawamori T, Mori H, Wakabayashi K.

Histol Histopathol. 2003 Jan;18(1):39-48.


Celecoxib inhibits N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder cancers in male B6D2F1 mice and female Fischer-344 rats.

Grubbs CJ, Lubet RA, Koki AT, Leahy KM, Masferrer JL, Steele VE, Kelloff GJ, Hill DL, Seibert K.

Cancer Res. 2000 Oct 15;60(20):5599-602.


Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin: comparison with the protective effect of beta-carotene.

Tanaka T, Makita H, Ohnishi M, Hirose Y, Wang A, Mori H, Satoh K, Hara A, Ogawa H.

Cancer Res. 1994 Sep 1;54(17):4653-9.


Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis in rats by flavonoids diosmin and hesperidin, each alone and in combination.

Tanaka T, Makita H, Ohnishi M, Mori H, Satoh K, Hara A, Sumida T, Fukutani K, Tanaka T, Ogawa H.

Cancer Res. 1997 Jan 15;57(2):246-52.


Increased expression of cyclooxygenase (COX)-2 in DMBA-induced hamster cheek pouch carcinogenesis and chemopreventive effect of a selective COX-2 inhibitor celecoxib.

Nishimura N, Urade M, Hashitani S, Noguchi K, Manno Y, Takaoka K, Sakurai K.

J Oral Pathol Med. 2004 Nov;33(10):614-21.


Chemoprevention of 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis by the dietary flavonoids chalcone, 2-hydroxychalcone, and quercetin.

Makita H, Tanaka T, Fujitsuka H, Tatematsu N, Satoh K, Hara A, Mori H.

Cancer Res. 1996 Nov 1;56(21):4904-9.


Suppressive effects of a selective cyclooxygenase-2 inhibitor, etodolac, on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.

Yamamoto K, Kitayama W, Denda A, Morisaki A, Kuniyasu H, Inoue M, Kirita T.

Exp Toxicol Pathol. 2004 Dec;56(3):145-51.


Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis.

Kawamori T, Rao CV, Seibert K, Reddy BS.

Cancer Res. 1998 Feb 1;58(3):409-12.


Piroxicam is an ineffective inhibitor of N-nitrosomethylbenzylamine-induced tumorigenesis in the rat esophagus.

Carlton PS, Gopalakrishnan R, Gupta A, Liston BW, Habib S, Morse MA, Stoner GD.

Cancer Res. 2002 Aug 1;62(15):4376-82.


Inhibition of 4-nitroquinoline-1-oxide-induced rat oral carcinogenesis by dietary exposure of a new retinoidal butenolide, KYN-54, during the initiation and post-initiation phases.

Makita H, Tanaka T, Ohnishi M, Tamai Y, Torihara M, Yamahara J, Mori H, Satoh K, Hara A.

Carcinogenesis. 1995 Sep;16(9):2171-6.


Chemoprevention of 4-NQO-induced oral carcinogenesis by co-administration of all-trans retinoic acid loaded microspheres and celecoxib.

Park K, Yang JH, Choi Y, Lee C, Kim SY, Byun Y.

J Control Release. 2005 May 5;104(1):167-79.


The effects of L-748706, a selective cyclooxygenase-2 inhibitor, on N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.

Stoner GD, Qin H, Chen T, Carlton PS, Rose ME, Aziz RM, Dixit R.

Carcinogenesis. 2005 Sep;26(9):1590-5. Epub 2005 May 5.

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