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Results: 1 to 20 of 130

1.

alphaB-crystallin regulation of angiogenesis by modulation of VEGF.

Kase S, He S, Sonoda S, Kitamura M, Spee C, Wawrousek E, Ryan SJ, Kannan R, Hinton DR.

Blood. 2010 Apr 22;115(16):3398-406. doi: 10.1182/blood-2009-01-197095. Epub 2009 Dec 18.

PMID:
20023214
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Decorin inhibits angiogenic potential of choroid-retinal endothelial cells by downregulating hypoxia-induced Met, Rac1, HIF-1α and VEGF expression in cocultured retinal pigment epithelial cells.

Du S, Wang S, Wu Q, Hu J, Li T.

Exp Eye Res. 2013 Nov;116:151-60. doi: 10.1016/j.exer.2013.08.019. Epub 2013 Sep 6.

PMID:
24016866
[PubMed - indexed for MEDLINE]
3.

Retinal pigment epithelium is protected against apoptosis by alphaB-crystallin.

Alge CS, Priglinger SG, Neubauer AS, Kampik A, Zillig M, Bloemendal H, Welge-Lussen U.

Invest Ophthalmol Vis Sci. 2002 Nov;43(11):3575-82.

PMID:
12407170
[PubMed - indexed for MEDLINE]
Free Article
4.

Focal adhesion kinase signaling pathway participates in the formation of choroidal neovascularization and regulates the proliferation and migration of choroidal microvascular endothelial cells by acting through HIF-1 and VEGF expression in RPE cells.

Zhu J, Wang YS, Zhang J, Zhao W, Yang XM, Li X, Jiang TS, Yao LB.

Exp Eye Res. 2009 May;88(5):910-8. doi: 10.1016/j.exer.2008.11.034. Epub 2008 Dec 14.

PMID:
19111720
[PubMed - indexed for MEDLINE]
5.

Impacts of hypoxia-inducible factor-1 knockout in the retinal pigment epithelium on choroidal neovascularization.

Lin M, Hu Y, Chen Y, Zhou KK, Jin J, Zhu M, Le YZ, Ge J, Ma JX.

Invest Ophthalmol Vis Sci. 2012 Sep 14;53(10):6197-206. doi: 10.1167/iovs.11-8936.

PMID:
22915031
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Inhibition of proliferation, migration and tube formation of choroidal microvascular endothelial cells by targeting HIF-1alpha with short hairpin RNA-expressing plasmid DNA in human RPE cells in a coculture system.

Zhao W, Wang YS, Hui YN, Zhu J, Zhang P, Li X, Dou GR.

Graefes Arch Clin Exp Ophthalmol. 2008 Oct;246(10):1413-22. doi: 10.1007/s00417-008-0858-8. Epub 2008 Jun 4.

PMID:
18523795
[PubMed - indexed for MEDLINE]
7.

αB-crystallin, an effector of unfolded protein response, confers anti-VEGF resistance to breast cancer via maintenance of intracrine VEGF in endothelial cells.

Ruan Q, Han S, Jiang WG, Boulton ME, Chen ZJ, Law BK, Cai J.

Mol Cancer Res. 2011 Dec;9(12):1632-43. doi: 10.1158/1541-7786.MCR-11-0327. Epub 2011 Oct 7.

PMID:
21984182
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress.

Yaung J, Jin M, Barron E, Spee C, Wawrousek EF, Kannan R, Hinton DR.

Mol Vis. 2007 Apr 4;13:566-77.

PMID:
17438522
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Human retinal pigment epithelium cell changes and expression of alphaB-crystallin: a biomarker for retinal pigment epithelium cell change in age-related macular degeneration.

De S, Rabin DM, Salero E, Lederman PL, Temple S, Stern JH.

Arch Ophthalmol. 2007 May;125(5):641-5.

PMID:
17502503
[PubMed - indexed for MEDLINE]
10.

Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia.

Yaung J, Kannan R, Wawrousek EF, Spee C, Sreekumar PG, Hinton DR.

Exp Eye Res. 2008 Feb;86(2):355-65. doi: 10.1016/j.exer.2007.11.007. Epub 2007 Nov 17.

PMID:
18191123
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Deficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction.

Dou G, Sreekumar PG, Spee C, He S, Ryan SJ, Kannan R, Hinton DR.

Free Radic Biol Med. 2012 Sep 1;53(5):1111-22. doi: 10.1016/j.freeradbiomed.2012.06.042. Epub 2012 Jul 8.

PMID:
22781655
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Increased expression of αA-crystallin in human diabetic eye.

Kase S, Ishida S, Rao NA.

Int J Mol Med. 2011 Oct;28(4):505-11. doi: 10.3892/ijmm.2011.708. Epub 2011 May 23.

PMID:
21617844
[PubMed - indexed for MEDLINE]
13.

Sensitization of RPE cells by alphaB-crystallin siRNA to SAHA-induced stage 1 apoptosis through abolishing the association of alphaB-crystallin with HDAC1 in SC35 speckles.

Noh SJ, Jeong WJ, Rho JH, Shin DM, Ahn HB, Park WC, Rho SH, Soung YH, Kim TH, Park BS, Yoo YH.

Invest Ophthalmol Vis Sci. 2008 Nov;49(11):4753-9. doi: 10.1167/iovs.08-2166. Epub 2008 Jun 14.

PMID:
18552382
[PubMed - indexed for MEDLINE]
Free Article
14.

alphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis.

Dimberg A, Rylova S, Dieterich LC, Olsson AK, Schiller P, Wikner C, Bohman S, Botling J, Lukinius A, Wawrousek EF, Claesson-Welsh L.

Blood. 2008 Feb 15;111(4):2015-23. Epub 2007 Dec 6.

PMID:
18063749
[PubMed - indexed for MEDLINE]
Free Article
15.

Alphab-crystallin expression in epiretinal membrane of human proliferative diabetic retinopathy.

Dong Z, Kase S, Ando R, Fukuhara J, Saito W, Kanda A, Murata M, Noda K, Ishida S.

Retina. 2012 Jun;32(6):1190-6. doi: 10.1097/IAE.0b013e318233ab9c.

PMID:
22371118
[PubMed - indexed for MEDLINE]
16.

Targeting the IRE1α/XBP1 and ATF6 arms of the unfolded protein response enhances VEGF blockade to prevent retinal and choroidal neovascularization.

Liu L, Qi X, Chen Z, Shaw L, Cai J, Smith LH, Grant MB, Boulton ME.

Am J Pathol. 2013 Apr;182(4):1412-24. doi: 10.1016/j.ajpath.2012.12.020. Epub 2013 Feb 8.

PMID:
23395094
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Differential expression of alphaB-crystallin and evidence of its role as a mediator of matrix gene expression in osteoarthritis.

Lambrecht S, Verbruggen G, Elewaut D, Deforce D.

Arthritis Rheum. 2009 Jan;60(1):179-88. doi: 10.1002/art.24152.

PMID:
19116904
[PubMed - indexed for MEDLINE]
Free Article
18.

Attenuation of choroidal neovascularization by β(2)-adrenoreceptor antagonism.

Lavine JA, Sang Y, Wang S, Ip MS, Sheibani N.

JAMA Ophthalmol. 2013 Mar;131(3):376-82. doi: 10.1001/jamaophthalmol.2013.1476.

PMID:
23303344
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

7-Ketocholesterol is present in lipid deposits in the primate retina: potential implication in the induction of VEGF and CNV formation.

Moreira EF, Larrayoz IM, Lee JW, Rodríguez IR.

Invest Ophthalmol Vis Sci. 2009 Feb;50(2):523-32. doi: 10.1167/iovs.08-2373. Epub 2008 Oct 20.

PMID:
18936140
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Role of PI3K/Akt and MEK/ERK in mediating hypoxia-induced expression of HIF-1alpha and VEGF in laser-induced rat choroidal neovascularization.

Yang XM, Wang YS, Zhang J, Li Y, Xu JF, Zhu J, Zhao W, Chu DK, Wiedemann P.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1873-9. doi: 10.1167/iovs.08-2591. Epub 2008 Dec 20.

PMID:
19098317
[PubMed - indexed for MEDLINE]
Free Article

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