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Items: 1 to 20 of 98

1.

ENU mutagenesis to generate genetically modified rat models.

van Boxtel R, Gould MN, Cuppen E, Smits BM.

Methods Mol Biol. 2010;597:151-67. doi: 10.1007/978-1-60327-389-3_11.

PMID:
20013232
2.

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals.

van Boxtel R, Toonen PW, Verheul M, van Roekel HS, Nijman IJ, Guryev V, Cuppen E.

BMC Genomics. 2008 Oct 7;9:460. doi: 10.1186/1471-2164-9-460.

3.

Generation of genetically modified rodents using random ENU mutagenesis.

van Boxtel R, Cuppen E.

Methods Mol Biol. 2011;693:295-308. doi: 10.1007/978-1-60761-974-1_18.

PMID:
21080288
4.

Highly Efficient ENU Mutagenesis in Zebrafish.

de Bruijn E, Cuppen E, Feitsma H.

Methods Mol Biol. 2009;546:3-12. doi: 10.1007/978-1-60327-977-2_1.

PMID:
19378094
5.

Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis.

Smits BM, Mudde JB, van de Belt J, Verheul M, Olivier J, Homberg J, Guryev V, Cools AR, Ellenbroek BA, Plasterk RH, Cuppen E.

Pharmacogenet Genomics. 2006 Mar;16(3):159-69.

PMID:
16495775
6.

Efficient gene-driven germ-line point mutagenesis of C57BL/6J mice.

Michaud EJ, Culiat CT, Klebig ML, Barker PE, Cain KT, Carpenter DJ, Easter LL, Foster CM, Gardner AW, Guo ZY, Houser KJ, Hughes LA, Kerley MK, Liu Z, Olszewski RE, Pinn I, Shaw GD, Shinpock SG, Wymore AM, Rinchik EM, Johnson DK.

BMC Genomics. 2005 Nov 21;6:164.

7.

Mismatch repair deficiency does not enhance ENU mutagenesis in the zebrafish germ line.

Feitsma H, de Bruijn E, van de Belt J, Nijman IJ, Cuppen E.

Mutagenesis. 2008 Jul;23(4):325-9. doi: 10.1093/mutage/gen019. Epub 2008 May 9.

8.

Retake the center stage--new development of rat genetics.

Zheng S, Geghman K, Shenoy S, Li C.

J Genet Genomics. 2012 Jun 20;39(6):261-8. doi: 10.1016/j.jgg.2012.05.003. Epub 2012 May 12. Review.

PMID:
22749013
9.

Transgenic lambda medaka as a new model for germ cell mutagenesis.

Winn RN, Majeske AJ, Jagoe CH, Glenn TC, Smith MH, Norris MB.

Environ Mol Mutagen. 2008 Apr;49(3):173-84. doi: 10.1002/em.20364.

PMID:
18213652
10.
11.
12.

Mouse ENU mutagenesis.

Justice MJ, Noveroske JK, Weber JS, Zheng B, Bradley A.

Hum Mol Genet. 1999;8(10):1955-63. Review.

13.

Production of knockout rats using ENU mutagenesis and a yeast-based screening assay.

Zan Y, Haag JD, Chen KS, Shepel LA, Wigington D, Wang YR, Hu R, Lopez-Guajardo CC, Brose HL, Porter KI, Leonard RA, Hitt AA, Schommer SL, Elegbede AF, Gould MN.

Nat Biotechnol. 2003 Jun;21(6):645-51. Epub 2003 May 18.

PMID:
12754522
14.

Efficient and fast targeted production of murine models based on ENU mutagenesis.

Augustin M, Sedlmeier R, Peters T, Huffstadt U, Kochmann E, Simon D, Schöniger M, Garke-Mayerthaler S, Laufs J, Mayhaus M, Franke S, Klose M, Graupner A, Kurzmann M, Zinser C, Wolf A, Voelkel M, Kellner M, Kilian M, Seelig S, Koppius A, Teubner A, Korthaus D, Nehls M, Wattler S.

Mamm Genome. 2005 Jun;16(6):405-13.

PMID:
16075367
15.

Identification of a rat model for usher syndrome type 1B by N-ethyl-N-nitrosourea mutagenesis-driven forward genetics.

Smits BM, Peters TA, Mul JD, Croes HJ, Fransen JA, Beynon AJ, Guryev V, Plasterk RH, Cuppen E.

Genetics. 2005 Aug;170(4):1887-96. Epub 2005 Jun 18.

16.

Techniques for optimizing the creation of mutations in zebrafish using N-ethyl-N-nitrosourea.

Trevarrow B.

Lab Anim (NY). 2011 Oct 20;40(11):353-61. doi: 10.1038/laban1111-353.

PMID:
22012195
17.

Spontaneous and ENU-induced mutation spectra at the cII locus in Big Blue Rat2 embryonic fibroblasts.

Watson DE, Cunningham ML, Tindall KR.

Mutagenesis. 1998 Sep;13(5):487-97.

18.

A gene-driven ENU-based approach to generating an allelic series in any gene.

Quwailid MM, Hugill A, Dear N, Vizor L, Wells S, Horner E, Fuller S, Weedon J, McMath H, Woodman P, Edwards D, Campbell D, Rodger S, Carey J, Roberts A, Glenister P, Lalanne Z, Parkinson N, Coghill EL, McKeone R, Cox S, Willan J, Greenfield A, Keays D, Brady S, Spurr N, Gray I, Hunter J, Brown SD, Cox RD.

Mamm Genome. 2004 Aug;15(8):585-91.

PMID:
15457338
19.

Large-scale N-ethyl-N-nitrosourea mutagenesis of mice--from phenotypes to genes.

Rathkolb B, Fuchs E, Kolb HJ, Renner-Müller I, Krebs O, Balling R, Hrabé de Angelis M, Wolf E.

Exp Physiol. 2000 Nov;85(6):635-44. Review.

PMID:
11187959
20.

Transmission of mutations in the lacI transgene to the offspring of ENU-treated Big Blue male mice.

Barnett LB, Tyl RW, Shane BS, Shelby MD, Lewis SE.

Environ Mol Mutagen. 2002;40(4):251-7.

PMID:
12489115
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