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Items: 1 to 20 of 123

1.

Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo.

Müller F, Mutch NJ, Schenk WA, Smith SA, Esterl L, Spronk HM, Schmidbauer S, Gahl WA, Morrissey JH, Renné T.

Cell. 2009 Dec 11;139(6):1143-56. doi: 10.1016/j.cell.2009.11.001.

PMID:
20005807
2.

Platelet polyphosphates: the nexus of primary and secondary hemostasis.

Müller F, Renné T.

Scand J Clin Lab Invest. 2011 Apr;71(2):82-6. doi: 10.3109/00365513.2010.550312. Review.

PMID:
21385010
3.

Factor XII promotes blood coagulation independent of factor XI in the presence of long-chain polyphosphates.

Puy C, Tucker EI, Wong ZC, Gailani D, Smith SA, Choi SH, Morrissey JH, Gruber A, McCarty OJ.

J Thromb Haemost. 2013 Jul;11(7):1341-52. doi: 10.1111/jth.12295.

PMID:
23659638
4.

The polyphosphate-factor XII pathway drives coagulation in prostate cancer-associated thrombosis.

Nickel KF, Ronquist G, Langer F, Labberton L, Fuchs TA, Bokemeyer C, Sauter G, Graefen M, Mackman N, Stavrou EX, Ronquist G, Renné T.

Blood. 2015 Sep 10;126(11):1379-89. doi: 10.1182/blood-2015-01-622811. Epub 2015 Jul 7.

PMID:
26153520
5.

Polyphosphates: a link between platelet activation, intrinsic coagulation and inflammation?

van der Meijden PE, Heemskerk JW.

Expert Rev Hematol. 2010 Jun;3(3):269-72. doi: 10.1586/ehm.10.26.

PMID:
21082980
6.

Polyphosphate: a link between platelets, coagulation and inflammation.

Morrissey JH.

Int J Hematol. 2012 Apr;95(4):346-52. doi: 10.1007/s12185-012-1054-5. Epub 2012 Apr 5. Review.

PMID:
22477540
7.

[Platelet polyphosphates: new mediators linking thrombosis with inflammation].

Kerbiriou-Nabias D.

Med Sci (Paris). 2010 Apr;26(4):343-6. doi: 10.1051/medsci/2010264343. French. No abstract available.

PMID:
20412734
8.

Inositol hexakisphosphate kinase 1 maintains hemostasis in mice by regulating platelet polyphosphate levels.

Ghosh S, Shukla D, Suman K, Lakshmi BJ, Manorama R, Kumar S, Bhandari R.

Blood. 2013 Aug 22;122(8):1478-86. doi: 10.1182/blood-2013-01-481549. Epub 2013 Jun 19.

PMID:
23782934
9.

Zinc-dependent contact system activation induces vascular leakage and hypotension in rodents.

Björkqvist J, Lecher B, Maas C, Renné T.

Biol Chem. 2013 Sep;394(9):1195-204. doi: 10.1515/hsz-2013-0144.

PMID:
23640941
10.

Plasma contact system activation drives anaphylaxis in severe mast cell-mediated allergic reactions.

Sala-Cunill A, Björkqvist J, Senter R, Guilarte M, Cardona V, Labrador M, Nickel KF, Butler L, Luengo O, Kumar P, Labberton L, Long A, Di Gennaro A, Kenne E, Jämsä A, Krieger T, Schlüter H, Fuchs T, Flohr S, Hassiepen U, Cumin F, McCrae K, Maas C, Stavrou E, Renné T.

J Allergy Clin Immunol. 2015 Apr;135(4):1031-43.e6. doi: 10.1016/j.jaci.2014.07.057. Epub 2014 Sep 18.

PMID:
25240785
11.

Platelets promote coagulation factor XII-mediated proteolytic cascade systems in plasma.

Johne J, Blume C, Benz PM, Pozgajová M, Ullrich M, Schuh K, Nieswandt B, Walter U, Renné T.

Biol Chem. 2006 Feb;387(2):173-8.

PMID:
16497149
12.

Novel family of insect salivary inhibitors blocks contact pathway activation by binding to polyphosphate, heparin, and dextran sulfate.

Alvarenga PH, Xu X, Oliveira F, Chagas AC, Nascimento CR, Francischetti IM, Juliano MA, Juliano L, Scharfstein J, Valenzuela JG, Ribeiro JM, Andersen JF.

Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2759-70. doi: 10.1161/ATVBAHA.113.302482. Epub 2013 Oct 3.

PMID:
24092749
13.

The procoagulant and proinflammatory plasma contact system.

Renné T.

Semin Immunopathol. 2012 Jan;34(1):31-41. doi: 10.1007/s00281-011-0288-2. Epub 2011 Aug 20. Review.

PMID:
21858560
14.

Novel roles for factor XII-driven plasma contact activation system.

Müller F, Renné T.

Curr Opin Hematol. 2008 Sep;15(5):516-21. doi: 10.1097/MOH.0b013e328309ec85. Review.

PMID:
18695377
15.

Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo.

Oschatz C, Maas C, Lecher B, Jansen T, Björkqvist J, Tradler T, Sedlmeier R, Burfeind P, Cichon S, Hammerschmidt S, Müller-Esterl W, Wuillemin WA, Nilsson G, Renné T.

Immunity. 2011 Feb 25;34(2):258-68. doi: 10.1016/j.immuni.2011.02.008.

PMID:
21349432
16.

Pathogenic mechanisms of bradykinin mediated diseases: dysregulation of an innate inflammatory pathway.

Kaplan AP, Joseph K.

Adv Immunol. 2014;121:41-89. doi: 10.1016/B978-0-12-800100-4.00002-7. Review.

PMID:
24388213
17.

FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow.

Zhu S, Travers RJ, Morrissey JH, Diamond SL.

Blood. 2015 Sep 17;126(12):1494-502. doi: 10.1182/blood-2015-04-641472. Epub 2015 Jul 1.

PMID:
26136249
18.

Putting polyphosphates to the test: evidence against platelet-induced activation of factor XII.

Faxälv L, Boknäs N, Ström JO, Tengvall P, Theodorsson E, Ramström S, Lindahl TL.

Blood. 2013 Nov 28;122(23):3818-24. doi: 10.1182/blood-2013-05-499384. Epub 2013 Jul 29.

PMID:
23896408
19.

Polyphosphate is a cofactor for the activation of factor XI by thrombin.

Choi SH, Smith SA, Morrissey JH.

Blood. 2011 Dec 22;118(26):6963-70. doi: 10.1182/blood-2011-07-368811. Epub 2011 Oct 5.

PMID:
21976677
20.

Dual role of collagen in factor XII-dependent thrombus formation.

van der Meijden PE, Munnix IC, Auger JM, Govers-Riemslag JW, Cosemans JM, Kuijpers MJ, Spronk HM, Watson SP, Renné T, Heemskerk JW.

Blood. 2009 Jul 23;114(4):881-90. doi: 10.1182/blood-2008-07-171066. Epub 2009 Apr 16.

PMID:
19372258
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