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Results: 1 to 20 of 102

1.

Haspin: a newly discovered regulator of mitotic chromosome behavior.

Higgins JM.

Chromosoma. 2010 Apr;119(2):137-47. doi: 10.1007/s00412-009-0250-4. Epub 2009 Dec 8. Review.

PMID:
19997740
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Regulation of mitotic chromosome cohesion by Haspin and Aurora B.

Dai J, Sullivan BA, Higgins JM.

Dev Cell. 2006 Nov;11(5):741-50.

PMID:
17084365
[PubMed - indexed for MEDLINE]
Free Article
3.

The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment.

Dai J, Sultan S, Taylor SS, Higgins JM.

Genes Dev. 2005 Feb 15;19(4):472-88. Epub 2005 Jan 28.

PMID:
15681610
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Haspin: a mitotic histone kinase required for metaphase chromosome alignment.

Dai J, Higgins JM.

Cell Cycle. 2005 May;4(5):665-8. Epub 2005 May 4.

PMID:
15846065
[PubMed - indexed for MEDLINE]
Free Article
5.

Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation.

Wang F, Ulyanova NP, Daum JR, Patnaik D, Kateneva AV, Gorbsky GJ, Higgins JM.

J Cell Biol. 2012 Oct 15;199(2):251-68. doi: 10.1083/jcb.201205106.

PMID:
23071152
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Structure, function and evolution of haspin and haspin-related proteins, a distinctive group of eukaryotic protein kinases.

Higgins JM.

Cell Mol Life Sci. 2003 Mar;60(3):446-62. Review.

PMID:
12737306
[PubMed - indexed for MEDLINE]
7.

Identification and characterization of plant Haspin kinase as a histone H3 threonine kinase.

Kurihara D, Matsunaga S, Omura T, Higashiyama T, Fukui K.

BMC Plant Biol. 2011 Apr 28;11:73. doi: 10.1186/1471-2229-11-73.

PMID:
21527018
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Yeast haspin kinase regulates polarity cues necessary for mitotic spindle positioning and is required to tolerate mitotic arrest.

Panigada D, Grianti P, Nespoli A, Rotondo G, Castro DG, Quadri R, Piatti S, Plevani P, Muzi-Falconi M.

Dev Cell. 2013 Sep 16;26(5):483-95. doi: 10.1016/j.devcel.2013.07.013. Epub 2013 Aug 22.

PMID:
23973165
[PubMed - indexed for MEDLINE]
9.

A positive feedback loop involving Haspin and Aurora B promotes CPC accumulation at centromeres in mitosis.

Wang F, Ulyanova NP, van der Waal MS, Patnaik D, Lens SM, Higgins JM.

Curr Biol. 2011 Jun 21;21(12):1061-9. doi: 10.1016/j.cub.2011.05.016. Epub 2011 Jun 9.

PMID:
21658950
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis.

Wang F, Dai J, Daum JR, Niedzialkowska E, Banerjee B, Stukenberg PT, Gorbsky GJ, Higgins JM.

Science. 2010 Oct 8;330(6001):231-5. doi: 10.1126/science.1189435. Epub 2010 Aug 12.

PMID:
20705812
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin.

Huertas D, Soler M, Moreto J, Villanueva A, Martinez A, Vidal A, Charlton M, Moffat D, Patel S, McDermott J, Owen J, Brotherton D, Krige D, Cuthill S, Esteller M.

Oncogene. 2012 Mar 15;31(11):1408-18. doi: 10.1038/onc.2011.335. Epub 2011 Aug 1.

PMID:
21804608
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Alk1 and Alk2 are two new cell cycle-regulated haspin-like proteins in budding yeast.

Nespoli A, Vercillo R, di Nola L, Diani L, Giannattasio M, Plevani P, Muzi-Falconi M.

Cell Cycle. 2006 Jul;5(13):1464-71. Epub 2006 Jul 1.

PMID:
16855400
[PubMed - indexed for MEDLINE]
Free Article
13.

Structure and functional characterization of the atypical human kinase haspin.

Eswaran J, Patnaik D, Filippakopoulos P, Wang F, Stein RL, Murray JW, Higgins JM, Knapp S.

Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20198-203. doi: 10.1073/pnas.0901989106. Epub 2009 Nov 16.

PMID:
19918057
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Identification of small molecule inhibitors of the mitotic kinase haspin by high-throughput screening using a homogeneous time-resolved fluorescence resonance energy transfer assay.

Patnaik D, Jun Xian, Glicksman MA, Cuny GD, Stein RL, Higgins JM.

J Biomol Screen. 2008 Dec;13(10):1025-34. doi: 10.1177/1087057108326081. Epub 2008 Oct 31.

PMID:
18978305
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization.

Villa F, Capasso P, Tortorici M, Forneris F, de Marco A, Mattevi A, Musacchio A.

Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20204-9. doi: 10.1073/pnas.0908485106. Epub 2009 Nov 16.

PMID:
19918049
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Aurora B defines its own chromosomal targeting by opposing the recruitment of the phosphatase scaffold Repo-Man.

Qian J, Beullens M, Lesage B, Bollen M.

Curr Biol. 2013 Jun 17;23(12):1136-43. doi: 10.1016/j.cub.2013.05.017. Epub 2013 Jun 6.

PMID:
23746640
[PubMed - indexed for MEDLINE]
Free Article
17.

Two histone marks establish the inner centromere and chromosome bi-orientation.

Yamagishi Y, Honda T, Tanno Y, Watanabe Y.

Science. 2010 Oct 8;330(6001):239-43. doi: 10.1126/science.1194498.

PMID:
20929775
[PubMed - indexed for MEDLINE]
Free Article
18.

Autoinhibition and Polo-dependent multisite phosphorylation restrict activity of the histone H3 kinase Haspin to mitosis.

Ghenoiu C, Wheelock MS, Funabiki H.

Mol Cell. 2013 Dec 12;52(5):734-45. doi: 10.1016/j.molcel.2013.10.002. Epub 2013 Oct 31.

PMID:
24184212
[PubMed - indexed for MEDLINE]
19.

Studies of haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesion.

Dai J, Kateneva AV, Higgins JM.

J Cell Sci. 2009 Nov 15;122(Pt 22):4168-76. doi: 10.1242/jcs.054122.

PMID:
19910498
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Survivin reads phosphorylated histone H3 threonine 3 to activate the mitotic kinase Aurora B.

Kelly AE, Ghenoiu C, Xue JZ, Zierhut C, Kimura H, Funabiki H.

Science. 2010 Oct 8;330(6001):235-9. doi: 10.1126/science.1189505. Epub 2010 Aug 12.

PMID:
20705815
[PubMed - indexed for MEDLINE]
Free PMC Article

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