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Items: 1 to 20 of 110

1.

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, Zhang H, Frackelton EC, Hou C, Flory JH, Otieno G, Chiavacci RM, Grundmeier R, Castro M, Latiano A, Dallapiccola B, Stempak J, Abrams DJ, Taylor K, McGovern D; Western Regional Alliance for Pediatric IBD, Silber G, Wrobel I, Quiros A; International IBD Genetics Consortium, Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmuda MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ; NIDDK IBD Genetics Consortium, Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E; Belgian-French IBD Consortium; Wellcome Trust Case Control Consortium, Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwillam R, Tremelling M, Delukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ, Heyman MB, Ferry GD, Kirschner B, Lee J, Essers J, Grand R, Stephens M, Levine A, Piccoli D, Van Limbergen J, Cucchiara S, Monos DS, Guthery SL, Denson L, Wilson DC, Grant SF, Daly M, Silverberg MS, Satsangi J, Hakonarson H.

Nat Genet. 2009 Dec;41(12):1335-40. doi: 10.1038/ng.489. Epub 2009 Nov 15.

2.

Genetics of inflammatory bowel disease.

Satsangi J, Parkes M, Jewell DP, Bell JI.

Clin Sci (Lond). 1998 May;94(5):473-8. Review.

PMID:
9682668
3.

Genetic variants in TNF-alpha but not DLG5 are associated with inflammatory bowel disease in a large United Kingdom cohort.

Tremelling M, Waller S, Bredin F, Greenfield S, Parkes M.

Inflamm Bowel Dis. 2006 Mar;12(3):178-84.

PMID:
16534418
4.

Genetic determinants of pediatric inflammatory bowel disease: is age of onset genetically determined?

Scherr R, Essers J, Hakonarson H, Kugathasan S.

Dig Dis. 2009;27(3):236-9. doi: 10.1159/000228555. Epub 2009 Sep 24. Review.

PMID:
19786746
5.

Familial occurrence and inheritance studies in inflammatory bowel disease.

Binder V, Orholm M.

Neth J Med. 1996 Feb;48(2):53-6. Review.

PMID:
8819799
6.

Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease.

Satsangi J, Welsh KI, Bunce M, Julier C, Farrant JM, Bell JI, Jewell DP.

Lancet. 1996 May 4;347(9010):1212-7.

PMID:
8622450
7.

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, Büning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H; International IBD Genetics Consortium (IIBDGC), Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC, Cho JH.

Nature. 2012 Nov 1;491(7422):119-24. doi: 10.1038/nature11582.

8.

Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.

Kugathasan S, Baldassano RN, Bradfield JP, Sleiman PM, Imielinski M, Guthery SL, Cucchiara S, Kim CE, Frackelton EC, Annaiah K, Glessner JT, Santa E, Willson T, Eckert AW, Bonkowski E, Shaner JL, Smith RM, Otieno FG, Peterson N, Abrams DJ, Chiavacci RM, Grundmeier R, Mamula P, Tomer G, Piccoli DA, Monos DS, Annese V, Denson LA, Grant SF, Hakonarson H.

Nat Genet. 2008 Oct;40(10):1211-5. doi: 10.1038/ng.203. Epub 2008 Aug 31.

9.

Association of susceptibility locus for inflammatory bowel disease on chromosome 16 with both ulcerative colitis and Crohn's disease.

Farmer M, Hunt L, Eichenberger MR, Petras RE, Janosky JE, Galandiuk S.

Dig Dis Sci. 2001 Mar;46(3):632-6.

PMID:
11318544
10.

Genetic determinants associated with early age of diagnosis of IBD.

Connelly TM, Berg AS, Harris L 3rd, Brinton D, Deiling S, Koltun WA.

Dis Colon Rectum. 2015 Mar;58(3):321-7. doi: 10.1097/DCR.0000000000000274.

PMID:
25664710
11.

New IBD genetics: common pathways with other diseases.

Lees CW, Barrett JC, Parkes M, Satsangi J.

Gut. 2011 Dec;60(12):1739-53. doi: 10.1136/gut.2009.199679. Epub 2011 Feb 7. Review.

PMID:
21300624
12.

A population- and family-based study of Canadian families reveals association of HLA DRB1*0103 with colonic involvement in inflammatory bowel disease.

Silverberg MS, Mirea L, Bull SB, Murphy JE, Steinhart AH, Greenberg GR, McLeod RS, Cohen Z, Wade JA, Siminovitch KA.

Inflamm Bowel Dis. 2003 Jan;9(1):1-9.

PMID:
12656131
13.

Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes.

Christodoulou K, Wiskin AE, Gibson J, Tapper W, Willis C, Afzal NA, Upstill-Goddard R, Holloway JW, Simpson MA, Beattie RM, Collins A, Ennis S.

Gut. 2013 Jul;62(7):977-84. doi: 10.1136/gutjnl-2011-301833. Epub 2012 Apr 28.

14.

A genome scan in 260 inflammatory bowel disease-affected relative pairs.

Barmada MM, Brant SR, Nicolae DL, Achkar JP, Panhuysen CI, Bayless TM, Cho JH, Duerr RH.

Inflamm Bowel Dis. 2004 Sep;10(5):513-20.

PMID:
15472510
15.

Variants at the 3p21 locus influence susceptibility and phenotype both in adults and early-onset patients with inflammatory bowel disease.

Latiano A, Palmieri O, Corritore G, Valvano MR, Bossa F, Cucchiara S, Castro M, Riegler G, De Venuto D, D'Incà R, Andriulli A, Annese V.

Inflamm Bowel Dis. 2010 Jul;16(7):1108-17. doi: 10.1002/ibd.21176.

PMID:
20024904
16.

Susceptibility locus for inflammatory bowel disease on chromosome 16 has a role in Crohn's disease, but not in ulcerative colitis.

Ohmen JD, Yang HY, Yamamoto KK, Zhao HY, Ma Y, Bentley LG, Huang Z, Gerwehr S, Pressman S, McElree C, Targan S, Rotter JI, Fischel-Ghodsian N.

Hum Mol Genet. 1996 Oct;5(10):1679-83.

17.

Differences between adults and children: genetics and beyond.

Billiet T, Vermeire S.

Expert Rev Gastroenterol Hepatol. 2015 Feb;9(2):191-6. doi: 10.1586/17474124.2014.950228. Epub 2014 Aug 19. Review.

PMID:
25134842
18.

[Polymorphism of the microsatellites and tumor necrosis factor genes in chronic inflammatory bowel diseases].

Heresbach D, Ababou A, Bourienne A, Alizadeh M, Quelvennec E, Pagenault M, Dabadie A, Berre NH, Campion JP, Launois B, Gosselin M, Genetet B, Bretagne JF, Semana G.

Gastroenterol Clin Biol. 1997;21(8-9):555-61. French.

19.

CARD15 mutations in Dutch familial and sporadic inflammatory bowel disease and an overview of European studies.

van der Linde K, Boor PP, Houwing-Duistermaat JJ, Crusius BJ, Wilson PJ, Kuipers EJ, de Rooij FW.

Eur J Gastroenterol Hepatol. 2007 Jun;19(6):449-59. Review.

PMID:
17489054
20.

Genome-wide association identifies multiple ulcerative colitis susceptibility loci.

McGovern DP, Gardet A, Törkvist L, Goyette P, Essers J, Taylor KD, Neale BM, Ong RT, Lagacé C, Li C, Green T, Stevens CR, Beauchamp C, Fleshner PR, Carlson M, D'Amato M, Halfvarson J, Hibberd ML, Lördal M, Padyukov L, Andriulli A, Colombo E, Latiano A, Palmieri O, Bernard EJ, Deslandres C, Hommes DW, de Jong DJ, Stokkers PC, Weersma RK; NIDDK IBD Genetics Consortium, Sharma Y, Silverberg MS, Cho JH, Wu J, Roeder K, Brant SR, Schumm LP, Duerr RH, Dubinsky MC, Glazer NL, Haritunians T, Ippoliti A, Melmed GY, Siscovick DS, Vasiliauskas EA, Targan SR, Annese V, Wijmenga C, Pettersson S, Rotter JI, Xavier RJ, Daly MJ, Rioux JD, Seielstad M.

Nat Genet. 2010 Apr;42(4):332-7. doi: 10.1038/ng.549. Epub 2010 Mar 14. Erratum in: Nat Genet. 2011 Apr;43(4):388.

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