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Items: 1 to 20 of 117

1.

TRPC1 channels are critical for hypertrophic signaling in the heart.

Seth M, Zhang ZS, Mao L, Graham V, Burch J, Stiber J, Tsiokas L, Winn M, Abramowitz J, Rockman HA, Birnbaumer L, Rosenberg P.

Circ Res. 2009 Nov 6;105(10):1023-30. doi: 10.1161/CIRCRESAHA.109.206581. Epub 2009 Sep 24.

2.

Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling.

Bush EW, Hood DB, Papst PJ, Chapo JA, Minobe W, Bristow MR, Olson EN, McKinsey TA.

J Biol Chem. 2006 Nov 3;281(44):33487-96. Epub 2006 Sep 1.

3.

TRPC channels are necessary mediators of pathologic cardiac hypertrophy.

Wu X, Eder P, Chang B, Molkentin JD.

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7000-5. doi: 10.1073/pnas.1001825107. Epub 2010 Mar 29.

4.

Cardiac anti-remodelling effect of aerobic training is associated with a reduction in the calcineurin/NFAT signalling pathway in heart failure mice.

Oliveira RS, Ferreira JC, Gomes ER, Paixão NA, Rolim NP, Medeiros A, Guatimosim S, Brum PC.

J Physiol. 2009 Aug 1;587(Pt 15):3899-910. doi: 10.1113/jphysiol.2009.173948. Epub 2009 Jun 8.

5.

Upregulation of TRPC1 in the development of cardiac hypertrophy.

Ohba T, Watanabe H, Murakami M, Takahashi Y, Iino K, Kuromitsu S, Mori Y, Ono K, Iijima T, Ito H.

J Mol Cell Cardiol. 2007 Mar;42(3):498-507. Epub 2006 Dec 15.

PMID:
17174323
6.

TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling.

Kuwahara K, Wang Y, McAnally J, Richardson JA, Bassel-Duby R, Hill JA, Olson EN.

J Clin Invest. 2006 Dec;116(12):3114-26. Epub 2006 Nov 9.

7.

Upregulation of TRPC1 contributes to contractile function in isoproterenol-induced hypertrophic myocardium of rat.

Chen MS, Xiao JH, Wang Y, Xu BM, Gao L, Wang JL.

Cell Physiol Biochem. 2013;32(4):951-9. doi: 10.1159/000354498. Epub 2013 Oct 1.

PMID:
24107839
8.

Targeted disruption of Hspa4 gene leads to cardiac hypertrophy and fibrosis.

Mohamed BA, Barakat AZ, Zimmermann WH, Bittner RE, Mühlfeld C, Hünlich M, Engel W, Maier LS, Adham IM.

J Mol Cell Cardiol. 2012 Oct;53(4):459-68. doi: 10.1016/j.yjmcc.2012.07.014. Epub 2012 Aug 1.

PMID:
22884543
9.

Essential role of TRPC1 channels in cardiomyoblasts hypertrophy mediated by 5-HT2A serotonin receptors.

Vindis C, D'Angelo R, Mucher E, Nègre-Salvayre A, Parini A, Mialet-Perez J.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):979-83. doi: 10.1016/j.bbrc.2009.12.001. Epub 2009 Dec 11.

PMID:
20005206
10.

Trpc1 ion channel modulates phosphatidylinositol 3-kinase/Akt pathway during myoblast differentiation and muscle regeneration.

Zanou N, Schakman O, Louis P, Ruegg UT, Dietrich A, Birnbaumer L, Gailly P.

J Biol Chem. 2012 Apr 27;287(18):14524-34. doi: 10.1074/jbc.M112.341784. Epub 2012 Mar 6.

11.

Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy.

Wilkins BJ, Dai YS, Bueno OF, Parsons SA, Xu J, Plank DM, Jones F, Kimball TR, Molkentin JD.

Circ Res. 2004 Jan 9;94(1):110-8. Epub 2003 Dec 1.

12.

Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1α-mediated TRPC signalling.

Chu W, Wan L, Zhao D, Qu X, Cai F, Huo R, Wang N, Zhu J, Zhang C, Zheng F, Cai R, Dong D, Lu Y, Yang B.

J Cell Mol Med. 2012 Sep;16(9):2022-34. doi: 10.1111/j.1582-4934.2011.01497.x.

13.

Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.

Manso AM, Li R, Monkley SJ, Cruz NM, Ong S, Lao DH, Koshman YE, Gu Y, Peterson KL, Chen J, Abel ED, Samarel AM, Critchley DR, Ross RS.

J Biol Chem. 2013 Feb 8;288(6):4252-64. doi: 10.1074/jbc.M112.427484. Epub 2012 Dec 24.

14.

Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling.

Selvaraj S, Sun Y, Watt JA, Wang S, Lei S, Birnbaumer L, Singh BB.

J Clin Invest. 2012 Apr;122(4):1354-67. doi: 10.1172/JCI61332. Epub 2012 Mar 26.

15.

Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling.

Gao H, Wang F, Wang W, Makarewich CA, Zhang H, Kubo H, Berretta RM, Barr LA, Molkentin JD, Houser SR.

J Mol Cell Cardiol. 2012 Nov;53(5):657-67. doi: 10.1016/j.yjmcc.2012.08.005. Epub 2012 Aug 21.

16.

Molecular determinants mediating gating of Transient Receptor Potential Canonical (TRPC) channels by stromal interaction molecule 1 (STIM1).

Lee KP, Choi S, Hong JH, Ahuja M, Graham S, Ma R, So I, Shin DM, Muallem S, Yuan JP.

J Biol Chem. 2014 Mar 7;289(10):6372-82. doi: 10.1074/jbc.M113.546556. Epub 2014 Jan 24.

17.

Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart.

Kinoshita H, Kuwahara K, Nishida M, Jian Z, Rong X, Kiyonaka S, Kuwabara Y, Kurose H, Inoue R, Mori Y, Li Y, Nakagawa Y, Usami S, Fujiwara M, Yamada Y, Minami T, Ueshima K, Nakao K.

Circ Res. 2010 Jun 25;106(12):1849-60. doi: 10.1161/CIRCRESAHA.109.208314. Epub 2010 May 6.

18.

Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation.

Cattin ME, Wang J, Weldrick JJ, Roeske CL, Mak E, Thorn SL, DaSilva JN, Wang Y, Lusis AJ, Burgon PG.

J Biol Chem. 2015 Oct 30;290(44):26699-714. doi: 10.1074/jbc.M115.678433. Epub 2015 Sep 10.

PMID:
26359501
19.

Regulation of transient receptor potential canonical channel 1 (TRPC1) by sphingosine 1-phosphate in C2C12 myoblasts and its relevance for a role of mechanotransduction in skeletal muscle differentiation.

Formigli L, Sassoli C, Squecco R, Bini F, Martinesi M, Chellini F, Luciani G, Sbrana F, Zecchi-Orlandini S, Francini F, Meacci E.

J Cell Sci. 2009 May 1;122(Pt 9):1322-33. doi: 10.1242/jcs.035402. Epub 2009 Apr 7.

20.

PKC-dependent coupling of calcium permeation through transient receptor potential canonical 3 (TRPC3) to calcineurin signaling in HL-1 myocytes.

Poteser M, Schleifer H, Lichtenegger M, Schernthaner M, Stockner T, Kappe CO, Glasnov TN, Romanin C, Groschner K.

Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10556-61. doi: 10.1073/pnas.1106183108. Epub 2011 Jun 8. Erratum in: Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13876-8.

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