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Results: 1 to 20 of 103

1.

JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin.

Dawson MA, Bannister AJ, Göttgens B, Foster SD, Bartke T, Green AR, Kouzarides T.

Nature. 2009 Oct 8;461(7265):819-22. doi: 10.1038/nature08448. Epub 2009 Sep 27.

PMID:
19783980
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Janus kinase 2: an epigenetic 'writer' that activates leukemogenic genes.

He J, Zhang Y.

J Mol Cell Biol. 2010 Oct;2(5):231-3. doi: 10.1093/jmcb/mjp054. Epub 2010 Jan 5.

PMID:
20051435
[PubMed - indexed for MEDLINE]
Free Article
3.

LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease.

Griffiths DS, Li J, Dawson MA, Trotter MW, Cheng YH, Smith AM, Mansfield W, Liu P, Kouzarides T, Nichols J, Bannister AJ, Green AR, Göttgens B.

Nat Cell Biol. 2011 Jan;13(1):13-21. doi: 10.1038/ncb2135. Epub 2010 Dec 12.

PMID:
21151131
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Nuclear localization of lymphocyte-specific protein tyrosine kinase (Lck) and its role in regulating LIM domain only 2 (Lmo2) gene.

Venkitachalam S, Chueh FY, Yu CL.

Biochem Biophys Res Commun. 2012 Jan 20;417(3):1058-62. doi: 10.1016/j.bbrc.2011.12.095. Epub 2011 Dec 27.

PMID:
22222369
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Negative regulation of JAK2 by H3K9 methyltransferase G9a in leukemia.

Son HJ, Kim JY, Hahn Y, Seo SB.

Mol Cell Biol. 2012 Sep;32(18):3681-94. doi: 10.1128/MCB.00673-12. Epub 2012 Jul 16.

PMID:
22801367
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients.

Oram SH, Thoms JA, Pridans C, Janes ME, Kinston SJ, Anand S, Landry JR, Lock RB, Jayaraman PS, Huntly BJ, Pimanda JE, Göttgens B.

Oncogene. 2010 Oct 28;29(43):5796-808. doi: 10.1038/onc.2010.320. Epub 2010 Aug 2.

PMID:
20676125
[PubMed - indexed for MEDLINE]
7.

Three distinct patterns of histone H3Y41 phosphorylation mark active genes.

Dawson MA, Foster SD, Bannister AJ, Robson SC, Hannah R, Wang X, Xhemalce B, Wood AD, Green AR, Göttgens B, Kouzarides T.

Cell Rep. 2012 Sep 27;2(3):470-7. doi: 10.1016/j.celrep.2012.08.016. Epub 2012 Sep 20.

PMID:
22999934
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Phosphorylation of KRAB-associated protein 1 (KAP1) at Tyr-449, Tyr-458, and Tyr-517 by nuclear tyrosine kinases inhibits the association of KAP1 and heterochromatin protein 1α (HP1α) with heterochromatin.

Kubota S, Fukumoto Y, Aoyama K, Ishibashi K, Yuki R, Morinaga T, Honda T, Yamaguchi N, Kuga T, Tomonaga T, Yamaguchi N.

J Biol Chem. 2013 Jun 14;288(24):17871-83. doi: 10.1074/jbc.M112.437756. Epub 2013 May 4.

PMID:
23645696
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Chromosomal translocations and leukaemia: a role for LMO2 in T cell acute leukaemia, in transcription and in erythropoiesis.

Rabbitts TH, Axelson H, Forster A, Grutz G, Lavenir I, Larson R, Osada H, Valge-Archer V, Wadman I, Warren A.

Leukemia. 1997 Apr;11 Suppl 3:271-2.

PMID:
9209362
[PubMed - indexed for MEDLINE]
10.
11.

Phosphorylation of p27Kip1 by JAK2 directly links cytokine receptor signaling to cell cycle control.

Jäkel H, Weinl C, Hengst L.

Oncogene. 2011 Aug 11;30(32):3502-12. doi: 10.1038/onc.2011.68. Epub 2011 Mar 21.

PMID:
21423214
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

SH2B1 enhances leptin signaling by both Janus kinase 2 Tyr813 phosphorylation-dependent and -independent mechanisms.

Li Z, Zhou Y, Carter-Su C, Myers MG Jr, Rui L.

Mol Endocrinol. 2007 Sep;21(9):2270-81. Epub 2007 Jun 12.

PMID:
17565041
[PubMed - indexed for MEDLINE]
13.

JAK2 gets histone H3 rolling.

Sattler M, Griffin JD.

Cancer Cell. 2009 Nov 6;16(5):365-6. doi: 10.1016/j.ccr.2009.10.009. Review.

PMID:
19878867
[PubMed - indexed for MEDLINE]
Free Article
14.

Phosphorylation of the linker histone H1 by CDK regulates its binding to HP1alpha.

Hale TK, Contreras A, Morrison AJ, Herrera RE.

Mol Cell. 2006 Jun 9;22(5):693-9.

PMID:
16762841
[PubMed - indexed for MEDLINE]
Free Article
15.

The kinase domain of Jak2 mediates induction of bcl-2 and delays cell death in hematopoietic cells.

Sakai I, Kraft AS.

J Biol Chem. 1997 May 9;272(19):12350-8.

PMID:
9139679
[PubMed - indexed for MEDLINE]
Free Article
16.

TEL-JAK2 mediates constitutive activation of the phosphatidylinositol 3'-kinase/protein kinase B signaling pathway.

Nguyen MH, Ho JM, Beattie BK, Barber DL.

J Biol Chem. 2001 Aug 31;276(35):32704-13. Epub 2001 Jul 2.

PMID:
11435425
[PubMed - indexed for MEDLINE]
Free Article
17.
18.

Differential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-bbeta.

Rui L, Gunter DR, Herrington J, Carter-Su C.

Mol Cell Biol. 2000 May;20(9):3168-77.

PMID:
10757801
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway.

Chin H, Arai A, Wakao H, Kamiyama R, Miyasaka N, Miura O.

Blood. 1998 May 15;91(10):3734-45.

PMID:
9573010
[PubMed - indexed for MEDLINE]
Free Article
20.

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