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Determining the aetiology of pulmonary oedema by the oedema fluid-to-plasma protein ratio.

Ware LB, Fremont RD, Bastarache JA, Calfee CS, Matthay MA.

Eur Respir J. 2010 Feb;35(2):331-7. doi: 10.1183/09031936.00098709. Epub 2009 Sep 9.


VEGF levels in the alveolar compartment do not distinguish between ARDS and hydrostatic pulmonary oedema.

Ware LB, Kaner RJ, Crystal RG, Schane R, Trivedi NN, McAuley D, Matthay MA.

Eur Respir J. 2005 Jul;26(1):101-5.


Assessing pulmonary permeability by transpulmonary thermodilution allows differentiation of hydrostatic pulmonary edema from ALI/ARDS.

Monnet X, Anguel N, Osman D, Hamzaoui O, Richard C, Teboul JL.

Intensive Care Med. 2007 Mar;33(3):448-53. Epub 2007 Jan 13.


Clara cell protein (CC16), a marker of lung epithelial injury, is decreased in plasma and pulmonary edema fluid from patients with acute lung injury.

Kropski JA, Fremont RD, Calfee CS, Ware LB.

Chest. 2009 Jun;135(6):1440-7. doi: 10.1378/chest.08-2465. Epub 2009 Feb 2.


Angiopoietin-2, permeability oedema, occurrence and severity of ALI/ARDS in septic and non-septic critically ill patients.

van der Heijden M, van Nieuw Amerongen GP, Koolwijk P, van Hinsbergh VW, Groeneveld AB.

Thorax. 2008 Oct;63(10):903-9. doi: 10.1136/thx.2007.087387. Epub 2008 Jun 17.


Alveolar fluid clearance is faster in women with acute lung injury compared to men.

Bastarache JA, Ong T, Matthay MA, Ware LB.

J Crit Care. 2011 Jun;26(3):249-56. doi: 10.1016/j.jcrc.2010.06.005. Epub 2010 Aug 4.


Copeptin in the assessment of acute lung injury and cardiogenic pulmonary edema.

Lin Q, Fu F, Chen H, Zhu B.

Respir Med. 2012 Sep;106(9):1268-77. doi: 10.1016/j.rmed.2012.05.010. Epub 2012 Jun 22.


Effect of fluid loading with saline or colloids on pulmonary permeability, oedema and lung injury score after cardiac and major vascular surgery.

Verheij J, van Lingen A, Raijmakers PG, Rijnsburger ER, Veerman DP, Wisselink W, Girbes AR, Groeneveld AB.

Br J Anaesth. 2006 Jan;96(1):21-30. Epub 2005 Nov 25.


Increase in plasma protein concentration for diagnosing weaning-induced pulmonary oedema.

Anguel N, Monnet X, Osman D, Castelain V, Richard C, Teboul JL.

Intensive Care Med. 2008 Jul;34(7):1231-8. doi: 10.1007/s00134-008-1038-3. Epub 2008 Feb 23.


Plasma CC16 levels are associated with development of ALI/ARDS in patients with ventilator-associated pneumonia: a retrospective observational study.

Determann RM, Millo JL, Waddy S, Lutter R, Garrard CS, Schultz MJ.

BMC Pulm Med. 2009 Dec 3;9:49. doi: 10.1186/1471-2466-9-49.


Diagnostic utility of B-type natriuretic peptide in critically ill patients with pulmonary edema: a prospective cohort study.

Levitt JE, Vinayak AG, Gehlbach BK, Pohlman A, Van Cleve W, Hall JB, Kress JP.

Crit Care. 2008;12(1):R3. doi: 10.1186/cc6764. Epub 2008 Jan 14.


A novel alveolar type I cell-specific biochemical marker of human acute lung injury.

Newman V, Gonzalez RF, Matthay MA, Dobbs LG.

Am J Respir Crit Care Med. 2000 Mar;161(3 Pt 1):990-5.


Transfusion-related acute lung injury and pulmonary edema in critically ill patients: a retrospective study.

Rana R, Fernández-Pérez ER, Khan SA, Rana S, Winters JL, Lesnick TG, Moore SB, Gajic O.

Transfusion. 2006 Sep;46(9):1478-83.


Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome.

Albertine KH, Soulier MF, Wang Z, Ishizaka A, Hashimoto S, Zimmerman GA, Matthay MA, Ware LB.

Am J Pathol. 2002 Nov;161(5):1783-96.


The severity of shock is associated with impaired rates of net alveolar fluid clearance in clinical acute lung injury.

Zeyed YF, Bastarache JA, Matthay MA, Ware LB.

Am J Physiol Lung Cell Mol Physiol. 2012 Sep 15;303(6):L550-5. doi: 10.1152/ajplung.00190.2012. Epub 2012 Jul 20.


Hypoproteinemia as a marker of acute respiratory distress syndrome in critically ill patients with pulmonary edema.

Arif SK, Verheij J, Groeneveld AB, Raijmakers PG.

Intensive Care Med. 2002 Mar;28(3):310-7. Epub 2002 Feb 13.


Diagnostic utility of C-reactive protein combined with brain natriuretic peptide in acute pulmonary edema: a cross sectional study.

Komiya K, Ishii H, Teramoto S, Takahashi O, Eshima N, Yamaguchi O, Ebi N, Murakami J, Yamamoto H, Kadota J.

Respir Res. 2011 Jun 22;12:83. doi: 10.1186/1465-9921-12-83.


Decision support tool for early differential diagnosis of acute lung injury and cardiogenic pulmonary edema in medical critically ill patients.

Schmickl CN, Shahjehan K, Li G, Dhokarh R, Kashyap R, Janish C, Alsara A, Jaffe AS, Hubmayr RD, Gajic O.

Chest. 2012 Jan;141(1):43-50. doi: 10.1378/chest.11-1496. Epub 2011 Oct 26.

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