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Results: 1 to 20 of 106

1.

Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands.

Bisson WH, Koch DC, O'Donnell EF, Khalil SM, Kerkvliet NI, Tanguay RL, Abagyan R, Kolluri SK.

J Med Chem. 2009 Sep 24;52(18):5635-41. doi: 10.1021/jm900199u.

PMID:
19719119
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Structural and functional characterization of the aryl hydrocarbon receptor ligand binding domain by homology modeling and mutational analysis.

Pandini A, Denison MS, Song Y, Soshilov AA, Bonati L.

Biochemistry. 2007 Jan 23;46(3):696-708.

PMID:
17223691
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis.

Pandini A, Soshilov AA, Song Y, Zhao J, Bonati L, Denison MS.

Biochemistry. 2009 Jun 30;48(25):5972-83. doi: 10.1021/bi900259z.

PMID:
19456125
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Characterization of the region of the aryl hydrocarbon receptor required for ligand dependency of transactivation using chimeric receptor between Drosophila and Mus musculus.

Kudo K, Takeuchi T, Murakami Y, Ebina M, Kikuchi H.

Biochim Biophys Acta. 2009 Jun-Aug;1789(6-8):477-86. doi: 10.1016/j.bbagrm.2009.06.003. Epub 2009 Jun 25.

PMID:
19560568
[PubMed - indexed for MEDLINE]
5.

Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor.

Fraccalvieri D, Soshilov AA, Karchner SI, Franks DG, Pandini A, Bonati L, Hahn ME, Denison MS.

Biochemistry. 2013 Jan 29;52(4):714-25. doi: 10.1021/bi301457f. Epub 2013 Jan 14.

PMID:
23286227
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

New aryl hydrocarbon receptor homology model targeted to improve docking reliability.

Motto I, Bordogna A, Soshilov AA, Denison MS, Bonati L.

J Chem Inf Model. 2011 Nov 28;51(11):2868-81. doi: 10.1021/ci2001617. Epub 2011 Nov 2.

PMID:
21981577
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Specific ligand binding domain residues confer low dioxin responsiveness to AHR1β of Xenopus laevis.

Odio C, Holzman SA, Denison MS, Fraccalvieri D, Bonati L, Franks DG, Hahn ME, Powell WH.

Biochemistry. 2013 Mar 12;52(10):1746-54. doi: 10.1021/bi301722k. Epub 2013 Feb 27.

PMID:
23394719
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Functional analysis of aryl hydrocarbon receptor nuclear translocator interactions with aryl hydrocarbon receptor in the yeast two-hybrid system.

Yamaguchi Y, Kuo MT.

Biochem Pharmacol. 1995 Oct 12;50(8):1295-302.

PMID:
7488247
[PubMed - indexed for MEDLINE]
10.

Structure and dimerization properties of the aryl hydrocarbon receptor PAS-A domain.

Wu D, Potluri N, Kim Y, Rastinejad F.

Mol Cell Biol. 2013 Nov;33(21):4346-56. doi: 10.1128/MCB.00698-13. Epub 2013 Sep 3.

PMID:
24001774
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.
13.

Amino acid substitutions in the aryl hydrocarbon receptor ligand binding domain reveal YH439 as an atypical AhR activator.

Whelan F, Hao N, Furness SG, Whitelaw ML, Chapman-Smith A.

Mol Pharmacol. 2010 Jun;77(6):1037-46. doi: 10.1124/mol.109.062927. Epub 2010 Mar 15.

PMID:
20231332
[PubMed - indexed for MEDLINE]
Free Article
14.

Differential suppression of the aryl hydrocarbon receptor nuclear translocator-dependent function by an aryl hydrocarbon receptor PAS-A-derived inhibitory molecule.

Xie J, Huang X, Park MS, Pham HM, Chan WK.

Biochem Pharmacol. 2014 Mar 15;88(2):253-65. doi: 10.1016/j.bcp.2014.01.021. Epub 2014 Jan 28.

PMID:
24486526
[PubMed - indexed for MEDLINE]
15.

Identification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR.

Hao N, Whitelaw ML, Shearwin KE, Dodd IB, Chapman-Smith A.

Nucleic Acids Res. 2011 May;39(9):3695-709. doi: 10.1093/nar/gkq1336. Epub 2011 Jan 17.

PMID:
21245039
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Aryl hydrocarbon receptor and aryl hydrocarbon nuclear translocator expression in human and rat placentas and transcription activity in human trophoblast cultures.

Stejskalova L, Vecerova L, Peréz LM, Vrzal R, Dvorak Z, Nachtigal P, Pavek P.

Toxicol Sci. 2011 Sep;123(1):26-36. doi: 10.1093/toxsci/kfr150. Epub 2011 Jun 10.

PMID:
21666223
[PubMed - indexed for MEDLINE]
Free Article
17.

Role of the carboxy-terminal transactivation domain and active transcription in the ligand-induced and ligand-independent degradation of the mouse Ahb-1 receptor.

Pollenz RS, Popat J, Dougherty EJ.

Biochem Pharmacol. 2005 Nov 25;70(11):1623-33. Epub 2005 Oct 13.

PMID:
16226227
[PubMed - indexed for MEDLINE]
18.

Differential usage of nuclear export sequences regulates intracellular localization of the dioxin (aryl hydrocarbon) receptor.

Berg P, Pongratz I.

J Biol Chem. 2001 Nov 16;276(46):43231-8. Epub 2001 Aug 2.

PMID:
11486007
[PubMed - indexed for MEDLINE]
Free Article
19.
20.

The spineless-aristapedia and tango bHLH-PAS proteins interact to control antennal and tarsal development in Drosophila.

Emmons RB, Duncan D, Estes PA, Kiefel P, Mosher JT, Sonnenfeld M, Ward MP, Duncan I, Crews ST.

Development. 1999 Sep;126(17):3937-45.

PMID:
10433921
[PubMed - indexed for MEDLINE]
Free Article

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