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Items: 1 to 20 of 102

1.

Common fragile sites are characterized by histone hypoacetylation.

Jiang Y, Lucas I, Young DJ, Davis EM, Karrison T, Rest JS, Le Beau MM.

Hum Mol Genet. 2009 Dec 1;18(23):4501-12. doi: 10.1093/hmg/ddp410. Epub 2009 Aug 28.

2.

The complex basis underlying common fragile site instability in cancer.

Ozeri-Galai E, Bester AC, Kerem B.

Trends Genet. 2012 Jun;28(6):295-302. doi: 10.1016/j.tig.2012.02.006. Epub 2012 Mar 31. Review.

PMID:
22465609
3.

Stably transfected common fragile site sequences exhibit instability at ectopic sites.

Ragland RL, Glynn MW, Arlt MF, Glover TW.

Genes Chromosomes Cancer. 2008 Oct;47(10):860-72. doi: 10.1002/gcc.20591.

PMID:
18615677
4.

Impaired replication dynamics at the FRA3B common fragile site.

Palakodeti A, Lucas I, Jiang Y, Young DJ, Fernald AA, Karrison T, Le Beau MM.

Hum Mol Genet. 2010 Jan 1;19(1):99-110. doi: 10.1093/hmg/ddp470. Epub .

5.

Interplay between genetic and epigenetic factors governs common fragile site instability in cancer.

Ozeri-Galai E, Tur-Sinai M, Bester AC, Kerem B.

Cell Mol Life Sci. 2014 Dec;71(23):4495-506. doi: 10.1007/s00018-014-1719-8. Epub 2014 Oct 9. Review.

PMID:
25297918
6.

Common fragile sites: mechanisms of instability revisited.

Debatisse M, Le Tallec B, Letessier A, Dutrillaux B, Brison O.

Trends Genet. 2012 Jan;28(1):22-32. doi: 10.1016/j.tig.2011.10.003. Epub 2011 Nov 15. Review.

PMID:
22094264
7.

Plant 45S rDNA clusters are fragile sites and their instability is associated with epigenetic alterations.

Huang M, Li H, Zhang L, Gao F, Wang P, Hu Y, Yan S, Zhao L, Zhang Q, Tan J, Liu X, He S, Li L.

PLoS One. 2012;7(4):e35139. doi: 10.1371/journal.pone.0035139. Epub 2012 Apr 11.

8.

Updating the mechanisms of common fragile site instability: how to reconcile the different views?

Le Tallec B, Koundrioukoff S, Wilhelm T, Letessier A, Brison O, Debatisse M.

Cell Mol Life Sci. 2014 Dec;71(23):4489-94. doi: 10.1007/s00018-014-1720-2. Epub 2014 Sep 24. Review.

9.

Large transcription units unify copy number variants and common fragile sites arising under replication stress.

Wilson TE, Arlt MF, Park SH, Rajendran S, Paulsen M, Ljungman M, Glover TW.

Genome Res. 2015 Feb;25(2):189-200. doi: 10.1101/gr.177121.114. Epub 2014 Nov 4.

10.
11.

Oncogene-induced replication stress preferentially targets common fragile sites in preneoplastic lesions. A genome-wide study.

Tsantoulis PK, Kotsinas A, Sfikakis PP, Evangelou K, Sideridou M, Levy B, Mo L, Kittas C, Wu XR, Papavassiliou AG, Gorgoulis VG.

Oncogene. 2008 May 22;27(23):3256-64. Epub 2007 Dec 17.

PMID:
18084328
12.

RORA, a large common fragile site gene, is involved in cellular stress response.

Zhu Y, McAvoy S, Kuhn R, Smith DI.

Oncogene. 2006 May 11;25(20):2901-8.

PMID:
16462772
13.

Molecular characterization of common fragile sites as a strategy to discover cancer susceptibility genes.

Savelyeva L, Brueckner LM.

Cell Mol Life Sci. 2014 Dec;71(23):4561-75. doi: 10.1007/s00018-014-1723-z. Epub 2014 Sep 18. Review.

PMID:
25231336
14.

A genome-wide analysis of common fragile sites: what features determine chromosomal instability in the human genome?

Fungtammasan A, Walsh E, Chiaromonte F, Eckert KA, Makova KD.

Genome Res. 2012 Jun;22(6):993-1005. doi: 10.1101/gr.134395.111. Epub 2012 Mar 28.

15.

DNA-damage response in chromatin of ribosomal genes and the surrounding genome.

Foltánková V, Legartová S, Kozubek S, Hofer M, Bártová E.

Gene. 2013 Jun 15;522(2):156-67. doi: 10.1016/j.gene.2013.03.108. Epub 2013 Apr 6.

PMID:
23566839
16.

Genomic rearrangements at the FRA2H common fragile site frequently involve non-homologous recombination events across LTR and L1(LINE) repeats.

Brueckner LM, Sagulenko E, Hess EM, Zheglo D, Blumrich A, Schwab M, Savelyeva L.

Hum Genet. 2012 Aug;131(8):1345-59. doi: 10.1007/s00439-012-1165-3. Epub 2012 Apr 5.

PMID:
22476624
18.

Common fragile sites, extremely large genes, neural development and cancer.

Smith DI, Zhu Y, McAvoy S, Kuhn R.

Cancer Lett. 2006 Jan 28;232(1):48-57. Epub 2005 Oct 10. Review.

PMID:
16221525
19.

Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site.

Letessier A, Millot GA, Koundrioukoff S, Lachagès AM, Vogt N, Hansen RS, Malfoy B, Brison O, Debatisse M.

Nature. 2011 Feb 3;470(7332):120-3. doi: 10.1038/nature09745. Epub 2011 Jan 23.

PMID:
21258320
20.

Common fragile sites are conserved features of human and mouse chromosomes and relate to large active genes.

Helmrich A, Stout-Weider K, Hermann K, Schrock E, Heiden T.

Genome Res. 2006 Oct;16(10):1222-30. Epub 2006 Sep 5.

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