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Admixture mapping of obesity-related traits in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study.

Cheng CY, Reich D, Coresh J, Boerwinkle E, Patterson N, Li M, North KE, Tandon A, Bailey-Wilson JE, Wilson JG, Kao WH.

Obesity (Silver Spring). 2010 Mar;18(3):563-72. doi: 10.1038/oby.2009.282. Epub 2009 Aug 20.


Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X.

Cheng CY, Kao WH, Patterson N, Tandon A, Haiman CA, Harris TB, Xing C, John EM, Ambrosone CB, Brancati FL, Coresh J, Press MF, Parekh RS, Klag MJ, Meoni LA, Hsueh WC, Fejerman L, Pawlikowska L, Freedman ML, Jandorf LH, Bandera EV, Ciupak GL, Nalls MA, Akylbekova EL, Orwoll ES, Leak TS, Miljkovic I, Li R, Ursin G, Bernstein L, Ardlie K, Taylor HA, Boerwinckle E, Zmuda JM, Henderson BE, Wilson JG, Reich D.

PLoS Genet. 2009 May;5(5):e1000490. doi: 10.1371/journal.pgen.1000490. Epub 2009 May 22.


African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts.

Cheng CY, Reich D, Haiman CA, Tandon A, Patterson N, Selvin E, Akylbekova EL, Brancati FL, Coresh J, Boerwinkle E, Altshuler D, Taylor HA, Henderson BE, Wilson JG, Kao WH.

PLoS One. 2012;7(3):e32840. doi: 10.1371/journal.pone.0032840. Epub 2012 Mar 16. Erratum in: PLoS One. 2012;7(9). doi:10.1371/annotation/52e53d8e-a4bd-4419-951a-75ddcbaf6c5d. Elizabeth, Selvin [corrected to Selvin, Elizabeth].


Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study.

Bressler J, Kao WH, Pankow JS, Boerwinkle E.

PLoS One. 2010 May 20;5(5):e10521. doi: 10.1371/journal.pone.0010521.


Admixture mapping scans identify a locus affecting retinal vascular caliber in hypertensive African Americans: the Atherosclerosis Risk in Communities (ARIC) study.

Cheng CY, Reich D, Wong TY, Klein R, Klein BE, Patterson N, Tandon A, Li M, Boerwinkle E, Sharrett AR, Kao WH.

PLoS Genet. 2010 Apr 15;6(4):e1000908. doi: 10.1371/journal.pgen.1000908.


Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.

Wing MR, Ziegler JM, Langefeld CD, Roh BH, Palmer ND, Mayer-Davis EJ, Rewers MJ, Haffner SM, Wagenknecht LE, Bowden DW.

Int J Obes (Lond). 2011 Sep;35(9):1173-82. doi: 10.1038/ijo.2010.244. Epub 2010 Nov 23.


Interaction of FTO and physical activity level on adiposity in African-American and European-American adults: the ARIC study.

Demerath EW, Lutsey PL, Monda KL, Linda Kao WH, Bressler J, Pankow JS, North KE, Folsom AR.

Obesity (Silver Spring). 2011 Sep;19(9):1866-72. doi: 10.1038/oby.2011.131. Epub 2011 May 19.


Admixture mapping of quantitative trait loci for BMI in African Americans: evidence for loci on chromosomes 3q, 5q, and 15q.

Basu A, Tang H, Arnett D, Gu CC, Mosley T, Kardia S, Luke A, Tayo B, Cooper R, Zhu X, Risch N.

Obesity (Silver Spring). 2009 Jun;17(6):1226-31. doi: 10.1038/oby.2009.24. Epub 2009 Feb 19.


Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies.

Li S, Zhao JH, Luan J, Luben RN, Rodwell SA, Khaw KT, Ong KK, Wareham NJ, Loos RJ.

Am J Clin Nutr. 2010 Jan;91(1):184-90. doi: 10.3945/ajcn.2009.28403. Epub 2009 Oct 7.


Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, Najjar S, Nagaraja R, Orrú M, Usala G, Dei M, Lai S, Maschio A, Busonero F, Mulas A, Ehret GB, Fink AA, Weder AB, Cooper RS, Galan P, Chakravarti A, Schlessinger D, Cao A, Lakatta E, Abecasis GR.

PLoS Genet. 2007 Jul;3(7):e115.


Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study.

Tin A, Köttgen A, Folsom AR, Maruthur NM, Tajuddin SM, Nalls MA, Evans MK, Zonderman AB, Friedrich CA, Boerwinkle E, Coresh J, Kao WH.

BMC Genet. 2015 May 29;16:56. doi: 10.1186/s12863-015-0219-7.


Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans.

Deo RC, Wilson JG, Xing C, Lawson K, Kao WH, Reich D, Tandon A, Akylbekova E, Patterson N, Mosley TH Jr, Boerwinkle E, Taylor HA Jr.

PLoS One. 2011 Jan 24;6(1):e14581. doi: 10.1371/journal.pone.0014581.


Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies.

den Hoed M, Ekelund U, Brage S, Grontved A, Zhao JH, Sharp SJ, Ong KK, Wareham NJ, Loos RJ.

Diabetes. 2010 Nov;59(11):2980-8. doi: 10.2337/db10-0370. Epub 2010 Aug 19.


Genome-wide linkage and peak-wide association study of obesity-related quantitative traits in Caribbean Hispanics.

Dong C, Beecham A, Slifer S, Wang L, McClendon MS, Blanton SH, Rundek T, Sacco RL.

Hum Genet. 2011 Feb;129(2):209-19. doi: 10.1007/s00439-010-0916-2. Epub 2010 Nov 21.


Development and evaluation of a genetic risk score for obesity.

Belsky DW, Moffitt TE, Sugden K, Williams B, Houts R, McCarthy J, Caspi A.

Biodemography Soc Biol. 2013;59(1):85-100. doi: 10.1080/19485565.2013.774628.


Fine-mapping in African Americans of 8 recently discovered genetic loci for plasma lipids: the Jackson Heart Study.

Keebler ME, Deo RC, Surti A, Konieczkowski D, Guiducci C, Burtt N, Buxbaum SG, Sarpong DF, Steffes MW, Wilson JG, Taylor HA, Kathiresan S.

Circ Cardiovasc Genet. 2010 Aug;3(4):358-64. doi: 10.1161/CIRCGENETICS.109.914267. Epub 2010 Jun 22.


The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts.

Bressler J, Fornage M, Hanis CL, Kao WH, Lewis CE, McPherson R, Dent R, Mosley TH, Pennacchio LA, Boerwinkle E.

BMC Med Genet. 2009 Jun 12;10:56. doi: 10.1186/1471-2350-10-56.


Gender-specific associations between ADIPOQ gene polymorphisms and adiponectin levels and obesity in the Jackson Heart Study cohort.

Riestra P, Gebreab SY, Xu R, Khan RJ, Bidulescu A, Correa A, Tekola-Ayele F, Davis SK.

BMC Med Genet. 2015 Aug 20;16:65. doi: 10.1186/s12881-015-0214-x.


Implication of European-derived adiposity loci in African Americans.

Hester JM, Wing MR, Li J, Palmer ND, Xu J, Hicks PJ, Roh BH, Norris JM, Wagenknecht LE, Langefeld CD, Freedman BI, Bowden DW, Ng MC.

Int J Obes (Lond). 2012 Mar;36(3):465-73. doi: 10.1038/ijo.2011.131. Epub 2011 Jul 12.


Associations of variants in FTO and near MC4R with obesity traits in South Asian Indians.

Vasan SK, Fall T, Neville MJ, Antonisamy B, Fall CH, Geethanjali FS, Gu HF, Raghupathy P, Samuel P, Thomas N, Brismar K, Ingelsson E, Karpe F.

Obesity (Silver Spring). 2012 Nov;20(11):2268-77. doi: 10.1038/oby.2012.64. Epub 2012 Mar 16.

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