Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 152

1.

HIF prolyl hydroxylase inhibitors prevent neuronal death induced by mitochondrial toxins: therapeutic implications for Huntington's disease and Alzheimer's disease.

Niatsetskaya Z, Basso M, Speer RE, McConoughey SJ, Coppola G, Ma TC, Ratan RR.

Antioxid Redox Signal. 2010 Apr;12(4):435-43. doi: 10.1089/ars.2009.2800.

PMID:
19659431
[PubMed - indexed for MEDLINE]
Free PMC Article
2.
3.

Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-nitropropionate: implications for Huntington's disease.

Bizat N, Hermel JM, Boyer F, Jacquard C, Créminon C, Ouary S, Escartin C, Hantraye P, Kajewski S, Brouillet E.

J Neurosci. 2003 Jun 15;23(12):5020-30. Erratum in: J Neurosci. 2003 Oct 29;23(30):9960.

PMID:
12832525
[PubMed - indexed for MEDLINE]
Free Article
4.

Induction of hypoxia inducible factor-1 attenuates metabolic insults induced by 3-nitropropionic acid in rat C6 glioma cells.

Yang YT, Ju TC, Yang DI.

J Neurochem. 2005 May;93(3):513-25.

PMID:
15836611
[PubMed - indexed for MEDLINE]
5.

Probucol modulates oxidative stress and excitotoxicity in Huntington's disease models in vitro.

Colle D, Hartwig JM, Soares FA, Farina M.

Brain Res Bull. 2012 Mar 10;87(4-5):397-405. doi: 10.1016/j.brainresbull.2012.01.003. Epub 2012 Jan 11.

PMID:
22245028
[PubMed - indexed for MEDLINE]
Free Article
6.

Effects of prolyl hydroxylase inhibitors on adipogenesis and hypoxia inducible factor 1 alpha levels under normoxic conditions.

Floyd ZE, Kilroy G, Wu X, Gimble JM.

J Cell Biochem. 2007 Aug 15;101(6):1545-57.

PMID:
17370314
[PubMed - indexed for MEDLINE]
7.

Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease.

Lee DW, Rajagopalan S, Siddiq A, Gwiazda R, Yang L, Beal MF, Ratan RR, Andersen JK.

J Biol Chem. 2009 Oct 16;284(42):29065-76. doi: 10.1074/jbc.M109.000638. Epub 2009 Aug 13.

PMID:
19679656
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Differential involvement of cell cycle reactivation between striatal and cortical neurons in cell death induced by 3-nitropropionic acid.

Akashiba H, Ikegaya Y, Nishiyama N, Matsuki N.

J Biol Chem. 2008 Mar 7;283(10):6594-606. doi: 10.1074/jbc.M707730200. Epub 2008 Jan 8.

PMID:
18182390
[PubMed - indexed for MEDLINE]
Free Article
9.

Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases.

Knowles HJ, Tian YM, Mole DR, Harris AL.

Circ Res. 2004 Jul 23;95(2):162-9. Epub 2004 Jun 10.

PMID:
15192023
[PubMed - indexed for MEDLINE]
Free Article
10.

Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system.

Siddiq A, Ayoub IA, Chavez JC, Aminova L, Shah S, LaManna JC, Patton SM, Connor JR, Cherny RA, Volitakis I, Bush AI, Langsetmo I, Seeley T, Gunzler V, Ratan RR.

J Biol Chem. 2005 Dec 16;280(50):41732-43. Epub 2005 Oct 13.

PMID:
16227210
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Death of cortical and striatal neurons induced by mitochondrial defect involves differential molecular mechanisms.

Galas MC, Bizat N, Cuvelier L, Bantubungi K, Brouillet E, Schiffmann SN, Blum D.

Neurobiol Dis. 2004 Feb;15(1):152-9.

PMID:
14751780
[PubMed - indexed for MEDLINE]
12.

Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways.

Siddiq A, Aminova LR, Troy CM, Suh K, Messer Z, Semenza GL, Ratan RR.

J Neurosci. 2009 Jul 8;29(27):8828-38. doi: 10.1523/JNEUROSCI.1779-09.2009.

PMID:
19587290
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway.

Ruan Q, Lesort M, MacDonald ME, Johnson GV.

Hum Mol Genet. 2004 Apr 1;13(7):669-81. Epub 2004 Feb 12.

PMID:
14962977
[PubMed - indexed for MEDLINE]
Free Article
14.

Expression of HIF prolyl hydroxylase isozymes in growth plate chondrocytes: relationship between maturation and apoptotic sensitivity.

Terkhorn SP, Bohensky J, Shapiro IM, Koyama E, Srinivas V.

J Cell Physiol. 2007 Jan;210(1):257-65.

PMID:
17044072
[PubMed - indexed for MEDLINE]
15.
16.

Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro.

Pan Y, Mansfield KD, Bertozzi CC, Rudenko V, Chan DA, Giaccia AJ, Simon MC.

Mol Cell Biol. 2007 Feb;27(3):912-25. Epub 2006 Nov 13.

PMID:
17101781
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

HIF-prolyl hydroxylases and cardiovascular diseases.

Sen Banerjee S, Thirunavukkarasu M, Tipu Rishi M, Sanchez JA, Maulik N, Maulik G.

Toxicol Mech Methods. 2012 Jun;22(5):347-58. doi: 10.3109/15376516.2012.673088. Review.

PMID:
22424133
[PubMed - indexed for MEDLINE]
18.

Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.

Berchner-Pfannschmidt U, Yamac H, Trinidad B, Fandrey J.

J Biol Chem. 2007 Jan 19;282(3):1788-96. Epub 2006 Oct 23.

PMID:
17060326
[PubMed - indexed for MEDLINE]
Free Article
19.

Increased chemoresistance induced by inhibition of HIF-prolyl-hydroxylase domain enzymes.

Brökers N, Le-Huu S, Vogel S, Hagos Y, Katschinski DM, Kleinschmidt M.

Cancer Sci. 2010 Jan;101(1):129-36. doi: 10.1111/j.1349-7006.2009.01367.x. Epub 2009 Sep 14.

PMID:
19817749
[PubMed - indexed for MEDLINE]
20.

A novel class of prolyl hydroxylase inhibitors induces angiogenesis and exerts organ protection against ischemia.

Nangaku M, Izuhara Y, Takizawa S, Yamashita T, Fujii-Kuriyama Y, Ohneda O, Yamamoto M, van Ypersele de Strihou C, Hirayama N, Miyata T.

Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2548-54. Epub 2007 Oct 11.

PMID:
17932321
[PubMed - indexed for MEDLINE]
Free Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk