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Items: 1 to 20 of 110

1.

The HECT-type E3 ubiquitin ligase AIP2 inhibits activation-induced T-cell death by catalyzing EGR2 ubiquitination.

Chen A, Gao B, Zhang J, McEwen T, Ye SQ, Zhang D, Fang D.

Mol Cell Biol. 2009 Oct;29(19):5348-56. doi: 10.1128/MCB.00407-09. Epub 2009 Aug 3.

2.

E3 ubiquitin ligases as T cell anergy factors.

Mueller DL.

Nat Immunol. 2004 Sep;5(9):883-90. Review.

PMID:
15334084
3.
4.

Cutting edge: regulation of T cell activation threshold by CD28 costimulation through targeting Cbl-b for ubiquitination.

Zhang J, Bárdos T, Li D, Gál I, Vermes C, Xu J, Mikecz K, Finnegan A, Lipkowitz S, Glant TT.

J Immunol. 2002 Sep 1;169(5):2236-40.

5.

Foxp3 controls autoreactive T cell activation through transcriptional regulation of early growth response genes and E3 ubiquitin ligase genes, independently of thymic selection.

Chang X, Chen L, Wen J, Godfrey VL, Qiao G, Hussien Y, Zhang J, Gao JX.

Clin Immunol. 2006 Dec;121(3):274-85. Epub 2006 Aug 30.

PMID:
16945588
6.

Egr-2 and Egr-3 are negative regulators of T cell activation.

Safford M, Collins S, Lutz MA, Allen A, Huang CT, Kowalski J, Blackford A, Horton MR, Drake C, Schwartz RH, Powell JD.

Nat Immunol. 2005 May;6(5):472-80. Epub 2005 Apr 17. Erratum in: Nat Immunol. 2005 Jul;6(7):737.

PMID:
15834410
9.

CTLA-4 (CD152) inhibits T cell function by activating the ubiquitin ligase Itch.

Hoff H, Kolar P, Ambach A, Radbruch A, Brunner-Weinzierl MC.

Mol Immunol. 2010 Jun;47(10):1875-81. doi: 10.1016/j.molimm.2010.03.017. Epub 2010 Apr 24.

PMID:
20417562
10.

Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis.

Gao B, Lee SM, Chen A, Zhang J, Zhang DD, Kannan K, Ortmann RA, Fang D.

EMBO Rep. 2008 May;9(5):480-5. doi: 10.1038/embor.2008.37. Epub 2008 Mar 28.

11.

Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells.

Yang B, Gay DL, MacLeod MK, Cao X, Hala T, Sweezer EM, Kappler J, Marrack P, Oliver PM.

Nat Immunol. 2008 Dec;9(12):1356-63. doi: 10.1038/ni.1670. Epub 2008 Oct 19.

12.

h-Goliath, paralog of GRAIL, is a new E3 ligase protein, expressed in human leukocytes.

Guais A, Siegrist S, Solhonne B, Jouault H, Guellaën G, Bulle F.

Gene. 2006 Jun 7;374:112-20. Epub 2006 Mar 20.

PMID:
16549277
13.

Interaction between syntaxin 8 and HECTd3, a HECT domain ligase.

Zhang L, Kang L, Bond W, Zhang N.

Cell Mol Neurobiol. 2009 Feb;29(1):115-21. doi: 10.1007/s10571-008-9303-0. Epub 2008 Sep 27.

PMID:
18821010
14.
15.

The tyrosine kinase c-Abl protects c-Jun from ubiquitination-mediated degradation in T cells.

Gao B, Lee SM, Fang D.

J Biol Chem. 2006 Oct 6;281(40):29711-8. Epub 2006 Aug 10.

16.

GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells.

Anandasabapathy N, Ford GS, Bloom D, Holness C, Paragas V, Seroogy C, Skrenta H, Hollenhorst M, Fathman CG, Soares L.

Immunity. 2003 Apr;18(4):535-47.

17.

The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor.

Vecchione A, Marchese A, Henry P, Rotin D, Morrione A.

Mol Cell Biol. 2003 May;23(9):3363-72.

18.

COP1 functions as a FoxO1 ubiquitin E3 ligase to regulate FoxO1-mediated gene expression.

Kato S, Ding J, Pisck E, Jhala US, Du K.

J Biol Chem. 2008 Dec 19;283(51):35464-73. doi: 10.1074/jbc.M801011200. Epub 2008 Sep 24.

19.

The role of E3 ligases in autoimmunity and the regulation of autoreactive T cells.

Lin AE, Mak TW.

Curr Opin Immunol. 2007 Dec;19(6):665-73. Epub 2007 Nov 26. Review.

PMID:
18036806
20.

E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activity.

Guo H, Qiao G, Ying H, Li Z, Zhao Y, Liang Y, Yang L, Lipkowitz S, Penninger JM, Langdon WY, Zhang J.

Cell Rep. 2012 May 31;1(5):472-82.

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