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Items: 1 to 20 of 123

1.

New series of monoquaternary pyridinium oximes: Synthesis and reactivation potency for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase.

Bharate SB, Guo L, Reeves TE, Cerasoli DM, Thompson CM.

Bioorg Med Chem Lett. 2009 Sep 1;19(17):5101-4. doi: 10.1016/j.bmcl.2009.07.035. Epub 2009 Jul 10.

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In vitro reactivation of sarin inhibited electric eel acetylcholinesterase by bis-pyridinium oximes bearing methoxy ether linkages.

Acharya J, Gupta AK, Mazumder A, Dubey DK.

Toxicol In Vitro. 2008 Mar;22(2):525-30. Epub 2007 Oct 25.

PMID:
18061396
4.

Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents.

Renou J, Mercey G, Verdelet T, Păunescu E, Gillon E, Arboléas M, Loiodice M, Kliachyna M, Baati R, Nachon F, Jean L, Renard PY.

Chem Biol Interact. 2013 Mar 25;203(1):81-4. doi: 10.1016/j.cbi.2012.09.023. Epub 2012 Oct 27.

PMID:
23111374
5.

Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

Musilek K, Holas O, Kuca K, Jun D, Dohnal V, Opletalova V, Dolezal M.

Bioorg Med Chem Lett. 2007 Jun 1;17(11):3172-6. Epub 2007 Mar 13.

PMID:
17383875
6.

In vitro reactivation kinetics of paraoxon- and DFP-inhibited electric eel AChE using mono- and bis-pyridinium oximes.

Gupta B, Sharma R, Singh N, Kuca K, Acharya JR, Ghosh KK.

Arch Toxicol. 2014 Feb;88(2):381-90. doi: 10.1007/s00204-013-1136-z. Epub 2013 Sep 25.

PMID:
24065055
7.

In vitro reactivation potency of novel symmetrical bis-pyridinium oximes for electric eel acetylcholinesterase inhibited by nerve agent sarin.

Acharya J, Dubey DK, Kaushik MP.

Toxicol In Vitro. 2011 Dec;25(8):2135-9. doi: 10.1016/j.tiv.2011.06.014. Epub 2011 Jul 2.

PMID:
21745562
8.

Fluorinated pyridinium oximes as potential reactivators for acetylcholinesterases inhibited by paraoxon organophosphorus agent.

Jeong HC, Park NJ, Chae CH, Musilek K, Kassa J, Kuca K, Jung YS.

Bioorg Med Chem. 2009 Sep 1;17(17):6213-7. doi: 10.1016/j.bmc.2009.07.043. Epub 2009 Jul 25.

PMID:
19665386
9.

Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.

Musilek K, Holas O, Jun D, Dohnal V, Gunn-Moore F, Opletalova V, Dolezal M, Kuca K.

Bioorg Med Chem. 2007 Nov 1;15(21):6733-41. Epub 2007 Aug 10.

PMID:
17764957
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In vitro oxime reactivation of red blood cell acetylcholinesterase inhibited by methyl-paraoxon.

Petroianu GA, Arafat K, Nurulain SM, Kuca K, Kassa J.

J Appl Toxicol. 2007 Mar-Apr;27(2):168-75.

PMID:
17265452
12.

Synthesis and evaluation of novel analogues of vitamin B6 as reactivators of tabun and paraoxon inhibited acetylcholinesterase.

Gaso-Sokac D, Katalinić M, Kovarik Z, Busić V, Kovac S.

Chem Biol Interact. 2010 Sep 6;187(1-3):234-7. doi: 10.1016/j.cbi.2010.02.004. Epub 2010 Feb 6.

PMID:
20144593
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Potency of novel oximes to reactivate sarin inhibited human cholinesterases.

Jun D, Kuca K, Picha J, Koleckar V, Marek J.

Drug Chem Toxicol. 2008;31(1):1-9.

PMID:
18161504
15.

A new group of monoquaternary reactivators of acetylcholinesterase inhibited by nerve agents.

Picha J, Kuca K, Kivala M, Kohout M, Cabal J, Liska F.

J Enzyme Inhib Med Chem. 2005 Jun;20(3):233-7.

PMID:
16119193
16.

Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes.

Oh KA, Park NJ, Park NS, Kuca K, Jun D, Jung YS.

Chem Biol Interact. 2008 Sep 25;175(1-3):365-7. doi: 10.1016/j.cbi.2008.05.012. Epub 2008 May 16.

PMID:
18565503
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Synthesis and evaluation of novel bis-pyridinium oximes as reactivators of DFP-inhibited acetylcholinesterase.

Acharya J, Gupta AK, Dubey DK, Raza SK.

Eur J Med Chem. 2009 Mar;44(3):1335-40. doi: 10.1016/j.ejmech.2008.02.029. Epub 2008 Mar 7.

PMID:
18396353
20.

Quaternary salts of 3,3'-bis-pyridinium monooximes: synthesis and biological activity.

Sikder AK, Ghosh AK, Jaiswal DK.

J Pharm Sci. 1993 Mar;82(3):258-61.

PMID:
8450418
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