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Ku's essential role in keeping telomeres intact.

Indiviglio SM, Bertuch AA.

Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12217-8. doi: 10.1073/pnas.0906427106. Epub 2009 Jul 21. No abstract available.


Processing of human telomeres by the Werner syndrome protein.

Reddy S, Li B, Comai L.

Cell Cycle. 2010 Aug 15;9(16):3137-8. doi: 10.4161/cc.9.16.12952. Epub 2010 Aug 9. No abstract available.


Ku86 represses lethal telomere deletion events in human somatic cells.

Wang Y, Ghosh G, Hendrickson EA.

Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12430-5. doi: 10.1073/pnas.0903362106. Epub 2009 Jul 6.


TRF2 interaction with Ku heterotetramerization interface gives insight into c-NHEJ prevention at human telomeres.

Ribes-Zamora A, Indiviglio SM, Mihalek I, Williams CL, Bertuch AA.

Cell Rep. 2013 Oct 17;5(1):194-206. doi: 10.1016/j.celrep.2013.08.040. Epub 2013 Oct 3.


Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends.

Stellwagen AE, Haimberger ZW, Veatch JR, Gottschling DE.

Genes Dev. 2003 Oct 1;17(19):2384-95. Epub 2003 Sep 15.


Which end: dissecting Ku's function at telomeres and double-strand breaks.

Bertuch AA, Lundblad V.

Genes Dev. 2003 Oct 1;17(19):2347-50. Review. No abstract available.


Telomere maintenance is dependent on activities required for end repair of double-strand breaks.

Nugent CI, Bosco G, Ross LO, Evans SK, Salinger AP, Moore JK, Haber JE, Lundblad V.

Curr Biol. 1998 May 21;8(11):657-60.


Survival and growth of yeast without telomere capping by Cdc13 in the absence of Sgs1, Exo1, and Rad9.

Ngo HP, Lydall D.

PLoS Genet. 2010 Aug 19;6(8):e1001072. doi: 10.1371/journal.pgen.1001072.


The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends.

Bonetti D, Clerici M, Manfrini N, Lucchini G, Longhese MP.

PLoS One. 2010 Nov 30;5(11):e14142. doi: 10.1371/journal.pone.0014142.


Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.

Limbo O, Moiani D, Kertokalio A, Wyman C, Tainer JA, Russell P.

Nucleic Acids Res. 2012 Dec;40(22):11435-49. doi: 10.1093/nar/gks954. Epub 2012 Oct 17.


Telomere recombination and alternative telomere lengthening mechanisms.

Draskovic I, Londono Vallejo A.

Front Biosci (Landmark Ed). 2013 Jan 1;18:1-20. Review.


Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres.

Laroche T, Martin SG, Gotta M, Gorham HC, Pryde FE, Louis EJ, Gasser SM.

Curr Biol. 1998 May 21;8(11):653-6.


RECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenance.

Ghosh AK, Rossi ML, Singh DK, Dunn C, Ramamoorthy M, Croteau DL, Liu Y, Bohr VA.

J Biol Chem. 2012 Jan 2;287(1):196-209. doi: 10.1074/jbc.M111.295063. Epub 2011 Oct 28.


A means to a DNA end: the many roles of Ku.

Downs JA, Jackson SP.

Nat Rev Mol Cell Biol. 2004 May;5(5):367-78. Review. No abstract available.


Fission yeast Rhp51 is required for the maintenance of telomere structure in the absence of the Ku heterodimer.

Kibe T, Tomita K, Matsuura A, Izawa D, Kodaira T, Ushimaru T, Uritani M, Ueno M.

Nucleic Acids Res. 2003 Sep 1;31(17):5054-63.


MRX protects telomeric DNA at uncapped telomeres of budding yeast cdc13-1 mutants.

Foster SS, Zubko MK, Guillard S, Lydall D.

DNA Repair (Amst). 2006 Jul 13;5(7):840-51. Epub 2006 Jun 12.


Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping.

Dewar JM, Lydall D.

EMBO J. 2010 Dec 1;29(23):4020-34. doi: 10.1038/emboj.2010.267. Epub 2010 Nov 2.


The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks.

Ngo GH, Lydall D.

Nucleic Acids Res. 2015 May 26;43(10):5017-32. doi: 10.1093/nar/gkv409. Epub 2015 Apr 29.


Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells.

Truong LN, Li Y, Shi LZ, Hwang PY, He J, Wang H, Razavian N, Berns MW, Wu X.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7720-5. doi: 10.1073/pnas.1213431110. Epub 2013 Apr 22.

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