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Results: 1 to 20 of 101

1.

Structural and molecular basis of the assembly of the TRPP2/PKD1 complex.

Yu Y, Ulbrich MH, Li MH, Buraei Z, Chen XZ, Ong AC, Tong L, Isacoff EY, Yang J.

Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11558-63. doi: 10.1073/pnas.0903684106. Epub 2009 Jun 25.

PMID:
19556541
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach.

Zhu J, Yu Y, Ulbrich MH, Li MH, Isacoff EY, Honig B, Yang J.

Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10133-8. doi: 10.1073/pnas.1017669108. Epub 2011 Jun 3.

PMID:
21642537
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Function and regulation of TRPP2 at the plasma membrane.

Tsiokas L.

Am J Physiol Renal Physiol. 2009 Jul;297(1):F1-9. doi: 10.1152/ajprenal.90277.2008. Epub 2009 Feb 25. Review.

PMID:
19244406
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes.

Giamarchi A, Feng S, Rodat-Despoix L, Xu Y, Bubenshchikova E, Newby LJ, Hao J, Gaudioso C, Crest M, Lupas AN, Honoré E, Williamson MP, Obara T, Ong AC, Delmas P.

EMBO J. 2010 Apr 7;29(7):1176-91. doi: 10.1038/emboj.2010.18. Epub 2010 Feb 18.

PMID:
20168298
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A single amino acid residue constitutes the third dimerization domain essential for the assembly and function of the tetrameric polycystin-2 (TRPP2) channel.

Feng S, Rodat-Despoix L, Delmas P, Ong AC.

J Biol Chem. 2011 May 27;286(21):18994-9000. doi: 10.1074/jbc.M110.192286. Epub 2011 Apr 7.

PMID:
21474446
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Nephrocystin-1 forms a complex with polycystin-1 via a polyproline motif/SH3 domain interaction and regulates the apoptotic response in mammals.

Wodarczyk C, Distefano G, Rowe I, Gaetani M, Bricoli B, Muorah M, Spitaleri A, Mannella V, Ricchiuto P, Pema M, Castelli M, Casanova AE, Mollica L, Banzi M, Boca M, Antignac C, Saunier S, Musco G, Boletta A.

PLoS One. 2010 Sep 14;5(9):e12719. doi: 10.1371/journal.pone.0012719.

PMID:
20856870
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The versatile nature of the calcium-permeable cation channel TRPP2.

Giamarchi A, Padilla F, Coste B, Raoux M, Crest M, Honoré E, Delmas P.

EMBO Rep. 2006 Aug;7(8):787-93. Review.

PMID:
16880824
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Expression of the polycystin-1 C-terminal cytoplasmic tail increases Cl channel activity in Xenopus oocytes.

Chernova MN, Vandorpe DH, Clark JS, Alper SL.

Kidney Int. 2005 Aug;68(2):632-41.

PMID:
16014040
[PubMed - indexed for MEDLINE]
9.

PKD1 interacts with PKD2 through a probable coiled-coil domain.

Qian F, Germino FJ, Cai Y, Zhang X, Somlo S, Germino GG.

Nat Genet. 1997 Jun;16(2):179-83.

PMID:
9171830
[PubMed - indexed for MEDLINE]
10.

A pathogenic C terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7.

Miyagi K, Kiyonaka S, Yamada K, Miki T, Mori E, Kato K, Numata T, Sawaguchi Y, Numaga T, Kimura T, Kanai Y, Kawano M, Wakamori M, Nomura H, Koni I, Yamagishi M, Mori Y.

J Biol Chem. 2009 Dec 4;284(49):34400-12. doi: 10.1074/jbc.M109.015149. Epub 2009 Oct 7.

PMID:
19812035
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

TRPP2: Ca2+-permeable cation channel and more.

Giamarchi A, Padilla F, Crest M, Honore E, Delmas P.

Cell Mol Biol (Noisy-le-grand). 2006 Dec 30;52(8):105-14. Review.

PMID:
17535744
[PubMed - indexed for MEDLINE]
12.

PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation.

Gao H, Wang Y, Wegierski T, Skouloudaki K, Pütz M, Fu X, Engel C, Boehlke C, Peng H, Kuehn EW, Kim E, Kramer-Zucker A, Walz G.

Hum Mol Genet. 2010 Jan 1;19(1):16-24. doi: 10.1093/hmg/ddp463. Epub .

PMID:
19801576
[PubMed - indexed for MEDLINE]
Free Article
13.

The transient receptor potential channels TRPP2 and TRPC1 form a heterotetramer with a 2:2 stoichiometry and an alternating subunit arrangement.

Kobori T, Smith GD, Sandford R, Edwardson JM.

J Biol Chem. 2009 Dec 18;284(51):35507-13. doi: 10.1074/jbc.M109.060228. Epub .

PMID:
19850920
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Role of the polycytin-primary cilia complex in bone development and mechanosensing.

Xiao ZS, Quarles LD.

Ann N Y Acad Sci. 2010 Mar;1192:410-21. doi: 10.1111/j.1749-6632.2009.05239.x. Review.

PMID:
20392267
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Polycystin-2 activation by inositol 1,4,5-trisphosphate-induced Ca2+ release requires its direct association with the inositol 1,4,5-trisphosphate receptor in a signaling microdomain.

Sammels E, Devogelaere B, Mekahli D, Bultynck G, Missiaen L, Parys JB, Cai Y, Somlo S, De Smedt H.

J Biol Chem. 2010 Jun 11;285(24):18794-805. doi: 10.1074/jbc.M109.090662. Epub 2010 Apr 7.

PMID:
20375013
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

TRPP2 and autosomal dominant polycystic kidney disease.

Köttgen M.

Biochim Biophys Acta. 2007 Aug;1772(8):836-50. Epub 2007 Jan 17. Review.

PMID:
17292589
[PubMed - indexed for MEDLINE]
Free Article
17.

Submembraneous microtubule cytoskeleton: interaction of TRPP2 with the cell cytoskeleton.

Chen XZ, Li Q, Wu Y, Liang G, Lara CJ, Cantiello HF.

FEBS J. 2008 Oct;275(19):4675-83. doi: 10.1111/j.1742-4658.2008.06616.x. Epub 2008 Aug 27.

PMID:
18754774
[PubMed - indexed for MEDLINE]
18.

Molecular advances in autosomal dominant polycystic kidney disease.

Gallagher AR, Germino GG, Somlo S.

Adv Chronic Kidney Dis. 2010 Mar;17(2):118-30. doi: 10.1053/j.ackd.2010.01.002. Review.

PMID:
20219615
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Kidney injury molecule 1 (Kim1) is a novel ciliary molecule and interactor of polycystin 2.

Kuehn EW, Hirt MN, John AK, Muehlenhardt P, Boehlke C, Pütz M, Kramer-Zucker AG, Bashkurov M, van de Weyer PS, Kotsis F, Walz G.

Biochem Biophys Res Commun. 2007 Dec 28;364(4):861-6. doi: 10.1016/j.bbrc.2007.10.103. Epub 2007 Oct 26.

PMID:
18273441
[PubMed - indexed for MEDLINE]
20.

Identification and functional characterization of an N-terminal oligomerization domain for polycystin-2.

Feng S, Okenka GM, Bai CX, Streets AJ, Newby LJ, DeChant BT, Tsiokas L, Obara T, Ong AC.

J Biol Chem. 2008 Oct 17;283(42):28471-9. doi: 10.1074/jbc.M803834200. Epub 2008 Aug 13.

PMID:
18701462
[PubMed - indexed for MEDLINE]
Free PMC Article

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