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Items: 1 to 20 of 1556

1.

Interleukin-25 inhibits interleukin-12 production and Th1 cell-driven inflammation in the gut.

Caruso R, Sarra M, Stolfi C, Rizzo A, Fina D, Fantini MC, Pallone F, MacDonald TT, Monteleone G.

Gastroenterology. 2009 Jun;136(7):2270-9. doi: 10.1053/j.gastro.2009.02.049.

PMID:
19505427
2.

Interleukin 16 is up-regulated in Crohn's disease and participates in TNBS colitis in mice.

Keates AC, Castagliuolo I, Cruickshank WW, Qiu B, Arseneau KO, Brazer W, Kelly CP.

Gastroenterology. 2000 Oct;119(4):972-82.

PMID:
11040184
3.

Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution.

Heller F, Florian P, Bojarski C, Richter J, Christ M, Hillenbrand B, Mankertz J, Gitter AH, B├╝rgel N, Fromm M, Zeitz M, Fuss I, Strober W, Schulzke JD.

Gastroenterology. 2005 Aug;129(2):550-64.

PMID:
16083712
4.

Regulation of gut inflammation and th17 cell response by interleukin-21.

Fina D, Sarra M, Fantini MC, Rizzo A, Caruso R, Caprioli F, Stolfi C, Cardolini I, Dottori M, Boirivant M, Pallone F, Macdonald TT, Monteleone G.

Gastroenterology. 2008 Apr;134(4):1038-48. doi: 10.1053/j.gastro.2008.01.041. Epub 2008 Jan 17.

PMID:
18395085
5.

Interleukin-21 enhances T-helper cell type I signaling and interferon-gamma production in Crohn's disease.

Monteleone G, Monteleone I, Fina D, Vavassori P, Del Vecchio Blanco G, Caruso R, Tersigni R, Alessandroni L, Biancone L, Naccari GC, MacDonald TT, Pallone F.

Gastroenterology. 2005 Mar;128(3):687-94.

PMID:
15765404
6.

TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease.

Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Takayama T, Kitazume MT, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T.

Inflamm Bowel Dis. 2010 Apr;16(4):568-75. doi: 10.1002/ibd.21124.

PMID:
19834969
7.

T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn's disease.

Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Sakuraba A, Hitotsumatsu O, Ogata H, Koganei K, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T.

Gut. 2004 Sep;53(9):1303-8. Erratum in: Gut. 2004 Nov;53(11):1722.

8.

Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response.

Sato T, Nakai T, Tamura N, Okamoto S, Matsuoka K, Sakuraba A, Fukushima T, Uede T, Hibi T.

Gut. 2005 Sep;54(9):1254-62.

9.

Expression of a splice variant of CXCR3 in Crohn's disease patients; indication for a lymphocyte--epithelial cell interaction.

Manousou P, Kolios G, Drygiannakis I, Pyrovolaki K, Bourikas L, Papadaki HA, Kouroumalis E.

J Gastroenterol Hepatol. 2008 Dec;23(12):1823-33. doi: 10.1111/j.1440-1746.2008.05486.x. Epub 2008 Aug 28.

PMID:
18761554
10.

Cholera toxin subunit B inhibits IL-12 and IFN-{gamma} production and signaling in experimental colitis and Crohn's disease.

Coccia EM, Remoli ME, Di Giacinto C, Del Zotto B, Giacomini E, Monteleone G, Boirivant M.

Gut. 2005 Nov;54(11):1558-64. Epub 2005 Aug 16.

11.

Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease.

Parronchi P, Romagnani P, Annunziato F, Sampognaro S, Becchio A, Giannarini L, Maggi E, Pupilli C, Tonelli F, Romagnani S.

Am J Pathol. 1997 Mar;150(3):823-32.

12.

Anti-IL-6 receptor monoclonal antibody inhibits leukocyte recruitment and promotes T-cell apoptosis in a murine model of Crohn's disease.

Ito H, Hirotani T, Yamamoto M, Ogawa H, Kishimoto T.

J Gastroenterol. 2002 Nov;37 Suppl 14:56-61.

PMID:
12572867
13.
14.

Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn's disease.

Kanai T, Watanabe M, Okazawa A, Sato T, Yamazaki M, Okamoto S, Ishii H, Totsuka T, Iiyama R, Okamoto R, Ikeda M, Kurimoto M, Takeda K, Akira S, Hibi T.

Gastroenterology. 2001 Oct;121(4):875-88.

PMID:
11606501
15.

Mice deficient in Th1- and Th2-type cytokines develop distinct forms of hapten-induced colitis.

Dohi T, Fujihashi K, Kiyono H, Elson CO, McGhee JR.

Gastroenterology. 2000 Sep;119(3):724-33.

PMID:
10982767
16.

Evidence for the critical role of interleukin-12 but not interferon-gamma in the pathogenesis of experimental colitis in mice.

Tozawa K, Hanai H, Sugimoto K, Baba S, Sugimura H, Aoshi T, Uchijima M, Nagata T, Koide Y.

J Gastroenterol Hepatol. 2003 May;18(5):578-87.

PMID:
12702051
17.

Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice.

Elson CO, Cong Y, Weaver CT, Schoeb TR, McClanahan TK, Fick RB, Kastelein RA.

Gastroenterology. 2007 Jun;132(7):2359-70. Epub 2007 Apr 13.

PMID:
17570211
18.

Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells.

Monteleone G, Biancone L, Marasco R, Morrone G, Marasco O, Luzza F, Pallone F.

Gastroenterology. 1997 Apr;112(4):1169-78.

PMID:
9098000
19.
20.

Reciprocal IFN-gamma and TGF-beta responses regulate the occurrence of mucosal inflammation.

Strober W, Kelsall B, Fuss I, Marth T, Ludviksson B, Ehrhardt R, Neurath M.

Immunol Today. 1997 Feb;18(2):61-4. Review.

PMID:
9057354
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