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Items: 1 to 20 of 137

1.

Mechanoenzymatic cleavage of the ultralarge vascular protein von Willebrand factor.

Zhang X, Halvorsen K, Zhang CZ, Wong WP, Springer TA.

Science. 2009 Jun 5;324(5932):1330-4. doi: 10.1126/science.1170905.

2.

Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.

Crawley JT, de Groot R, Xiang Y, Luken BM, Lane DA.

Blood. 2011 Sep 22;118(12):3212-21. doi: 10.1182/blood-2011-02-306597. Epub 2011 Jun 29. Review.

3.

Biochemistry. Force signaling in biology.

Gebhardt JC, Rief M.

Science. 2009 Jun 5;324(5932):1278-80. doi: 10.1126/science.1175874. No abstract available.

PMID:
19498156
4.

Shear-induced unfolding activates von Willebrand factor A2 domain for proteolysis.

Baldauf C, Schneppenheim R, Stacklies W, Obser T, Pieconka A, Schneppenheim S, Budde U, Zhou J, Gräter F.

J Thromb Haemost. 2009 Dec;7(12):2096-105. doi: 10.1111/j.1538-7836.2009.03640.x. Epub 2009 Oct 8.

PMID:
19817991
5.

Unfolding the A2 domain of von Willebrand factor with the optical trap.

Ying J, Ling Y, Westfield LA, Sadler JE, Shao JY.

Biophys J. 2010 Apr 21;98(8):1685-93. doi: 10.1016/j.bpj.2009.12.4324.

6.

Calcium stabilizes the von Willebrand factor A2 domain by promoting refolding.

Xu AJ, Springer TA.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3742-7. doi: 10.1073/pnas.1121261109. Epub 2012 Feb 22.

7.

Shear stress and von Willebrand factor in health and disease.

Tsai HM.

Semin Thromb Hemost. 2003 Oct;29(5):479-88. Review.

PMID:
14631548
8.

Conformational stability and domain unfolding of the Von Willebrand factor A domains.

Auton M, Cruz MA, Moake J.

J Mol Biol. 2007 Feb 23;366(3):986-1000. Epub 2006 Oct 25.

PMID:
17187823
9.

Calcium modulates force sensing by the von Willebrand factor A2 domain.

Jakobi AJ, Mashaghi A, Tans SJ, Huizinga EG.

Nat Commun. 2011 Jul 12;2:385. doi: 10.1038/ncomms1385.

10.

Binding of platelet glycoprotein Ibalpha to von Willebrand factor domain A1 stimulates the cleavage of the adjacent domain A2 by ADAMTS13.

Nishio K, Anderson PJ, Zheng XL, Sadler JE.

Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10578-83. Epub 2004 Jul 12.

11.

Simultaneous exposure of sites in von Willebrand factor for glycoprotein Ib binding and ADAMTS13 cleavage: studies with ristocetin.

Chen J, Ling M, Fu X, López JA, Chung DW.

Arterioscler Thromb Vasc Biol. 2012 Nov;32(11):2625-30. doi: 10.1161/ATVBAHA.112.254144. Epub 2012 Aug 23.

12.

Mechanisms by which von Willebrand disease mutations destabilize the A2 domain.

Xu AJ, Springer TA.

J Biol Chem. 2013 Mar 1;288(9):6317-24. doi: 10.1074/jbc.M112.422618. Epub 2013 Jan 15.

13.

Platelet-VWF complexes are preferred substrates of ADAMTS13 under fluid shear stress.

Shim K, Anderson PJ, Tuley EA, Wiswall E, Sadler JE.

Blood. 2008 Jan 15;111(2):651-7. Epub 2007 Sep 27.

14.

Degradation of circulating von Willebrand factor and its regulator ADAMTS13 implicates secreted Bacillus anthracis metalloproteases in anthrax consumptive coagulopathy.

Chung MC, Popova TG, Jorgensen SC, Dong L, Chandhoke V, Bailey CL, Popov SG.

J Biol Chem. 2008 Apr 11;283(15):9531-42. doi: 10.1074/jbc.M705871200. Epub 2008 Feb 8.

15.

C2362F mutation gives rise to an ADAMTS13-resistant von Willebrand factor.

Casonato A, Pontara E, Battiston M, Morpurgo M, Cattini MG, Casarin E, Saga G, Daidone V, De Marco L.

Thromb Haemost. 2013 Jun;109(6):999-1006. doi: 10.1160/TH12-11-0808. Epub 2013 Feb 28.

PMID:
23446343
16.

Escherichia coli-derived von Willebrand factor-A2 domain fluorescence/Förster resonance energy transfer proteins that quantify ADAMTS13 activity.

Dayananda KM, Gogia S, Neelamegham S.

Anal Biochem. 2011 Mar 15;410(2):206-13. doi: 10.1016/j.ab.2010.12.005. Epub 2010 Dec 10.

17.

Shear stress-induced unfolding of VWF accelerates oxidation of key methionine residues in the A1A2A3 region.

Fu X, Chen J, Gallagher R, Zheng Y, Chung DW, López JA.

Blood. 2011 Nov 10;118(19):5283-91. doi: 10.1182/blood-2011-01-331074. Epub 2011 Sep 13.

18.

Ultralarge von Willebrand factor multimers and normal ADAMTS13 activity in the umbilical cord blood.

Tsai HM, Sarode R, Downes KA.

Thromb Res. 2002 Nov 1;108(2-3):121-5.

PMID:
12590947
19.

[Von Willebrand factor and ADAMTS13 balancing primary haemostasis].

Schneppenheim R, Budde U.

Hamostaseologie. 2011 Nov;31(4):275-80. doi: 10.5482/ha-1167. Epub 2011 Jul 20. Review. German.

PMID:
21792464
20.

Von Willebrand factor: another janus-faced hemostasis protein.

Franchini M, Mannucci PM.

Semin Thromb Hemost. 2008 Oct;34(7):663-9. doi: 10.1055/s-0028-1104545. Epub 2008 Dec 15. Review.

PMID:
19085767
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