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Results: 1 to 20 of 382

1.

Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis.

Semenza GL.

Blood. 2009 Sep 3;114(10):2015-9. doi: 10.1182/blood-2009-05-189985. Epub 2009 Jun 3. Review.

PMID:
19494350
[PubMed - indexed for MEDLINE]
Free Article
2.

Hypoxia-inducible factor 1 (HIF-1) pathway.

Semenza GL.

Sci STKE. 2007 Oct 9;2007(407):cm8. Review.

PMID:
17925579
[PubMed - indexed for MEDLINE]
Free Article
3.

Regulation of gene expression by the hypoxia-inducible factors.

Fedele AO, Whitelaw ML, Peet DJ.

Mol Interv. 2002 Jul;2(4):229-43. Review.

PMID:
14993394
[PubMed - indexed for MEDLINE]
4.

von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.

Hickey MM, Lam JC, Bezman NA, Rathmell WK, Simon MC.

J Clin Invest. 2007 Dec;117(12):3879-89.

PMID:
17992257
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Erythrocytosis-associated HIF-2alpha mutations demonstrate a critical role for residues C-terminal to the hydroxylacceptor proline.

Furlow PW, Percy MJ, Sutherland S, Bierl C, McMullin MF, Master SR, Lappin TR, Lee FS.

J Biol Chem. 2009 Apr 3;284(14):9050-8. doi: 10.1074/jbc.M808737200. Epub 2009 Feb 10.

PMID:
19208626
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove.

Percy MJ, Furlow PW, Beer PA, Lappin TR, McMullin MF, Lee FS.

Blood. 2007 Sep 15;110(6):2193-6. Epub 2007 Jun 19.

PMID:
17579185
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Nitric oxide donor, (+/-)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1alpha by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation.

Park YK, Ahn DR, Oh M, Lee T, Yang EG, Son M, Park H.

Mol Pharmacol. 2008 Jul;74(1):236-45. doi: 10.1124/mol.108.045278. Epub 2008 Apr 21.

PMID:
18426857
[PubMed - indexed for MEDLINE]
Free Article
8.

Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors.

Aprelikova O, Chandramouli GV, Wood M, Vasselli JR, Riss J, Maranchie JK, Linehan WM, Barrett JC.

J Cell Biochem. 2004 Jun 1;92(3):491-501. Erratum in: J Cell Biochem. 2004 Oct 15;93(3):639.

PMID:
15156561
[PubMed - indexed for MEDLINE]
9.

The HIF pathway and erythrocytosis.

Lee FS, Percy MJ.

Annu Rev Pathol. 2011;6:165-92. doi: 10.1146/annurev-pathol-011110-130321. Review.

PMID:
20939709
[PubMed - indexed for MEDLINE]
10.

Hypoxia-inducible factors in the first trimester human lung.

Groenman F, Rutter M, Caniggia I, Tibboel D, Post M.

J Histochem Cytochem. 2007 Apr;55(4):355-63. Epub 2006 Dec 22.

PMID:
17189520
[PubMed - indexed for MEDLINE]
11.

Disturbance in the HIF-1alpha pathway associated with erythrocytosis: further evidences brought by frameshift and nonsense mutations in the prolyl hydroxylase domain protein 2 (PHD2) gene.

Al-Sheikh M, Moradkhani K, Lopez M, Wajcman H, Préhu C.

Blood Cells Mol Dis. 2008 Mar-Apr;40(2):160-5. Epub 2007 Oct 15.

PMID:
17933562
[PubMed - indexed for MEDLINE]
12.

Oxygen sensing: recent insights from idiopathic erythrocytosis.

Lee FS, Percy MJ, McMullin MF.

Cell Cycle. 2006 May;5(9):941-5. Epub 2006 May 1.

PMID:
16687917
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms.

Martín-Puig S, Temes E, Olmos G, Jones DR, Aragonés J, Landázuri MO.

J Biol Chem. 2004 Mar 5;279(10):9504-11. Epub 2003 Dec 17.

PMID:
14681229
[PubMed - indexed for MEDLINE]
Free Article
14.

Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha.

Chan DA, Sutphin PD, Yen SE, Giaccia AJ.

Mol Cell Biol. 2005 Aug;25(15):6415-26.

PMID:
16024780
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.

Osada R, Horiuchi A, Kikuchi N, Yoshida J, Hayashi A, Ota M, Katsuyama Y, Melillo G, Konishi I.

Hum Pathol. 2007 Sep;38(9):1310-20. Epub 2007 Jun 6. Erratum in: Hum Pathol. 2008 Jan;39(1):147. Mellilo, Giovanni [corrected to Melillo, Giovanni].

PMID:
17555795
[PubMed - indexed for MEDLINE]
16.

HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels.

Masson N, Ratcliffe PJ.

J Cell Sci. 2003 Aug 1;116(Pt 15):3041-9. Review.

PMID:
12829734
[PubMed - indexed for MEDLINE]
Free Article
17.

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.

Koivunen P, Hirsilä M, Günzler V, Kivirikko KI, Myllyharju J.

J Biol Chem. 2004 Mar 12;279(11):9899-904. Epub 2003 Dec 29.

PMID:
14701857
[PubMed - indexed for MEDLINE]
Free Article
18.

Suppression of hypoxia-inducible factor 1alpha (HIF-1alpha) transcriptional activity by the HIF prolyl hydroxylase EGLN1.

To KK, Huang LE.

J Biol Chem. 2005 Nov 11;280(45):38102-7. Epub 2005 Sep 12.

PMID:
16157596
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.

Franke K, Kalucka J, Mamlouk S, Singh RP, Muschter A, Weidemann A, Iyengar V, Jahn S, Wieczorek K, Geiger K, Muders M, Sykes AM, Poitz DM, Ripich T, Otto T, Bergmann S, Breier G, Baretton G, Fong GH, Greaves DR, Bornstein S, Chavakis T, Fandrey J, Gassmann M, Wielockx B.

Blood. 2013 Feb 21;121(8):1436-45. doi: 10.1182/blood-2012-08-449181. Epub 2012 Dec 20.

PMID:
23264599
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

von Hippel-Lindau protein adjusts oxygen sensing of the FIH asparaginyl hydroxylase.

Li SH, Chun YS, Lim JH, Huang LE, Park JW.

Int J Biochem Cell Biol. 2011 May;43(5):795-804. doi: 10.1016/j.biocel.2011.02.004. Epub 2011 Feb 21.

PMID:
21316481
[PubMed - indexed for MEDLINE]

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