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Results: 1 to 20 of 288

1.

Cytochrome P450-catalysed arene-epoxidation of the bioactive tea tree oil ingredient p-cymene: indication for the formation of a reactive allergenic intermediate?

Meesters RJ, Duisken M, Hollender J.

Xenobiotica. 2009 Sep;39(9):663-71. doi: 10.1080/00498250902989094.

PMID:
19480554
[PubMed - indexed for MEDLINE]
2.

Study on the cytochrome P450-mediated oxidative metabolism of the terpene alcohol linalool: indication of biological epoxidation.

Meesters RJ, Duisken M, Hollender J.

Xenobiotica. 2007 Jun;37(6):604-17.

PMID:
17614007
[PubMed - indexed for MEDLINE]
3.

Metabolism in rats of p-cymene derivatives: carvacrol and thymol.

Austgulen LT, Solheim E, Scheline RR.

Pharmacol Toxicol. 1987 Aug;61(2):98-102.

PMID:
2959918
[PubMed - indexed for MEDLINE]
4.

α-Terpinene, an antioxidant in tea tree oil, autoxidizes rapidly to skin allergens on air exposure.

Rudbäck J, Bergström MA, Börje A, Nilsson U, Karlberg AT.

Chem Res Toxicol. 2012 Mar 19;25(3):713-21. doi: 10.1021/tx200486f. Epub 2012 Feb 10.

PMID:
22250748
[PubMed - indexed for MEDLINE]
5.

Metabolism of Delta(3)-carene by human cytochrome p450 enzymes: identification and characterization of two new metabolites.

Duisken M, Benz D, Peiffer TH, Blömeke B, Hollender J.

Curr Drug Metab. 2005 Dec;6(6):593-601.

PMID:
16379671
[PubMed - indexed for MEDLINE]
6.

Identification of thymol phase I metabolites in human urine by headspace sorptive extraction combined with thermal desorption and gas chromatography mass spectrometry.

Thalhamer B, Buchberger W, Waser M.

J Pharm Biomed Anal. 2011 Aug 25;56(1):64-9. doi: 10.1016/j.jpba.2011.04.014. Epub 2011 Apr 22.

PMID:
21620603
[PubMed - indexed for MEDLINE]
7.

Degradation products of monoterpenes are the sensitizing agents in tea tree oil.

Hausen BM, Reichling J, Harkenthal M.

Am J Contact Dermat. 1999 Jun;10(2):68-77.

PMID:
10357714
[PubMed - indexed for MEDLINE]
8.

Radical intermediates in the catalytic oxidation of hydrocarbons by bacterial and human cytochrome P450 enzymes.

Jiang Y, He X, Ortiz de Montellano PR.

Biochemistry. 2006 Jan 17;45(2):533-42.

PMID:
16401082
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Tea tree oil allergy: what is the offending agent? Report of three cases of tea tree oil allergy and review of the literature.

Rubel DM, Freeman S, Southwell IA.

Australas J Dermatol. 1998 Nov;39(4):244-7. Review.

PMID:
9838722
[PubMed - indexed for MEDLINE]
10.

P450(BM-3)-catalyzed whole-cell biotransformation of alpha-pinene with recombinant Escherichia coli in an aqueous-organic two-phase system.

Schewe H, Holtmann D, Schrader J.

Appl Microbiol Biotechnol. 2009 Jul;83(5):849-57. doi: 10.1007/s00253-009-1917-8. Epub 2009 Mar 6.

PMID:
19266193
[PubMed - indexed for MEDLINE]
11.

Evaluation of tea tree oil quality and ascaridole: a deep study by means of chiral and multi heart-cuts multidimensional gas chromatography system coupled to mass spectrometry detection.

Sciarrone D, Ragonese C, Carnovale C, Piperno A, Dugo P, Dugo G, Mondello L.

J Chromatogr A. 2010 Oct 8;1217(41):6422-7. doi: 10.1016/j.chroma.2010.08.019. Epub 2010 Aug 13.

PMID:
20832072
[PubMed - indexed for MEDLINE]
12.

Inhibition of acetylcholinesterase by Tea Tree oil.

Mills C, Cleary BJ, Gilmer JF, Walsh JJ.

J Pharm Pharmacol. 2004 Mar;56(3):375-9.

PMID:
15025863
[PubMed - indexed for MEDLINE]
13.

Autoxidation of linalyl acetate, the main component of lavender oil, creates potent contact allergens.

Sköld M, Hagvall L, Karlberg AT.

Contact Dermatitis. 2008 Jan;58(1):9-14.

PMID:
18154552
[PubMed - indexed for MEDLINE]
14.

Thymol and carvacrol production from leaves of wild Palestinian Majorana syriaca.

Abu-Lafi S, Odeh I, Dewik H, Qabajah M, Hanus LO, Dembitsky VM.

Bioresour Technol. 2008 Jun;99(9):3914-8. Epub 2007 Sep 10.

PMID:
17826989
[PubMed - indexed for MEDLINE]
15.

Systemic availability and pharmacokinetics of thymol in humans.

Kohlert C, Schindler G, März RW, Abel G, Brinkhaus B, Derendorf H, Gräfe EU, Veit M.

J Clin Pharmacol. 2002 Jul;42(7):731-7.

PMID:
12092740
[PubMed - indexed for MEDLINE]
16.

Radical rebound mechanism in cytochrome P-450-catalyzed hydroxylation of the multifaceted radical clocks alpha- and beta-thujone.

He X, de Montellano PR.

J Biol Chem. 2004 Sep 17;279(38):39479-84. Epub 2004 Jul 17.

PMID:
15258138
[PubMed - indexed for MEDLINE]
Free Article
17.

Influence of electron transport proteins on the reactions catalyzed by Fusarium fujikuroi gibberellin monooxygenases.

Troncoso C, Cárcamo J, Hedden P, Tudzynski B, Rojas MC.

Phytochemistry. 2008 Feb;69(3):672-83. Epub 2007 Oct 24.

PMID:
17920091
[PubMed - indexed for MEDLINE]
18.

Cutaneous metabolic activation of carvoxime, a self-activating, skin-sensitizing prohapten.

Ott H, Bergström MA, Heise R, Skazik C, Zwadlo-Klarwasser G, Merk HF, Baron JM, Karlberg AT.

Chem Res Toxicol. 2009 Feb;22(2):399-405. doi: 10.1021/tx8003642.

PMID:
19125687
[PubMed - indexed for MEDLINE]
19.

Complex reactions catalyzed by cytochrome P450 enzymes.

Isin EM, Guengerich FP.

Biochim Biophys Acta. 2007 Mar;1770(3):314-29. Epub 2006 Jul 13. Review.

PMID:
17239540
[PubMed - indexed for MEDLINE]
Free Article
20.

Immediate systemic hypersensitivity reaction associated with topical application of Australian tea tree oil.

Mozelsio NB, Harris KE, McGrath KG, Grammer LC.

Allergy Asthma Proc. 2003 Jan-Feb;24(1):73-5.

PMID:
12635581
[PubMed - indexed for MEDLINE]

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