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Results: 1 to 20 of 103

Similar articles for PubMed (Select 19465930)

1.

Inhibitors paradoxically prime kinases.

Frye SV, Johnson GL.

Nat Chem Biol. 2009 Jul;5(7):448-9. doi: 10.1038/nchembio.f.11. No abstract available.

PMID:
19465930
2.

A small molecule discrimination map of the antibiotic resistance kinome.

Shakya T, Stogios PJ, Waglechner N, Evdokimova E, Ejim L, Blanchard JE, McArthur AG, Savchenko A, Wright GD.

Chem Biol. 2011 Dec 23;18(12):1591-601. doi: 10.1016/j.chembiol.2011.10.018.

3.

Lessons learned from molecular scaffold analysis.

Hu Y, Stumpfe D, Bajorath J.

J Chem Inf Model. 2011 Aug 22;51(8):1742-53. doi: 10.1021/ci200179y. Epub 2011 Jul 28. No abstract available.

PMID:
21755989
4.

The design, annotation, and application of a kinase-targeted library.

Xi H, Lunney EA.

Methods Mol Biol. 2011;685:279-91. doi: 10.1007/978-1-60761-931-4_14.

PMID:
20981529
5.

Design of targeted libraries against the human Chk1 kinase using PGVL Hub.

Peng Z, Hu Q.

Methods Mol Biol. 2011;685:321-36. doi: 10.1007/978-1-60761-931-4_16.

PMID:
20981531
6.

De novo design of protein kinase inhibitors by in silico identification of hinge region-binding fragments.

Urich R, Wishart G, Kiczun M, Richters A, Tidten-Luksch N, Rauh D, Sherborne B, Wyatt PG, Brenk R.

ACS Chem Biol. 2013 May 17;8(5):1044-52. doi: 10.1021/cb300729y. Epub 2013 Mar 27.

7.

Identification of novel inhibitors of tropomyosin-related kinase A through the structure-based virtual screening with homology-modeled protein structure.

Park H, Chi O, Kim J, Hong S.

J Chem Inf Model. 2011 Nov 28;51(11):2986-93. doi: 10.1021/ci200378s. Epub 2011 Nov 2.

PMID:
22017333
8.

Conformational analysis of the DFG-out kinase motif and biochemical profiling of structurally validated type II inhibitors.

Vijayan RS, He P, Modi V, Duong-Ly KC, Ma H, Peterson JR, Dunbrack RL Jr, Levy RM.

J Med Chem. 2015 Jan 8;58(1):466-79. doi: 10.1021/jm501603h. Epub 2014 Dec 12.

PMID:
25478866
9.

Fluorescence labels in kinases: a high-throughput kinase binding assay for the identification of DFG-out binding ligands.

Simard JR, Rauh D.

Methods Mol Biol. 2012;800:95-117. doi: 10.1007/978-1-61779-349-3_8.

PMID:
21964785
10.

Kinase inhibitor data modeling and de novo inhibitor design with fragment approaches.

Vieth M, Erickson J, Wang J, Webster Y, Mader M, Higgs R, Watson I.

J Med Chem. 2009 Oct 22;52(20):6456-66. doi: 10.1021/jm901147e.

PMID:
19791746
11.

Discovery of tyrosine kinase inhibitors by docking into an inactive kinase conformation generated by molecular dynamics.

Zhao H, Huang D, Caflisch A.

ChemMedChem. 2012 Nov;7(11):1983-90. doi: 10.1002/cmdc.201200331. Epub 2012 Sep 13.

PMID:
22976951
12.

Virtual target screening: validation using kinase inhibitors.

Santiago DN, Pevzner Y, Durand AA, Tran M, Scheerer RR, Daniel K, Sung SS, Woodcock HL, Guida WC, Brooks WH.

J Chem Inf Model. 2012 Aug 27;52(8):2192-203. doi: 10.1021/ci300073m. Epub 2012 Jul 23.

13.

Development and strategies of VEGFR-2/KDR inhibitors.

Huang L, Huang Z, Bai Z, Xie R, Sun L, Lin K.

Future Med Chem. 2012 Sep;4(14):1839-52. doi: 10.4155/fmc.12.121. Review.

PMID:
23043480
14.

Application of Free-Wilson selectivity analysis for combinatorial library design.

Sciabola S, Stanton RV, Johnson TL, Xi H.

Methods Mol Biol. 2011;685:91-109. doi: 10.1007/978-1-60761-931-4_5.

PMID:
20981520
15.

Target profiling of small molecules by chemical proteomics.

Rix U, Superti-Furga G.

Nat Chem Biol. 2009 Sep;5(9):616-24. doi: 10.1038/nchembio.216. Review.

PMID:
19690537
16.

Advancing the kinase field: new targets and second generation inhibitors.

Laufer S, Bajorath J.

J Med Chem. 2015 Jan 8;58(1):1. doi: 10.1021/jm5018708. Epub 2014 Dec 9. No abstract available.

PMID:
25490234
17.

Design, synthesis and selection of DNA-encoded small-molecule libraries.

Clark MA, Acharya RA, Arico-Muendel CC, Belyanskaya SL, Benjamin DR, Carlson NR, Centrella PA, Chiu CH, Creaser SP, Cuozzo JW, Davie CP, Ding Y, Franklin GJ, Franzen KD, Gefter ML, Hale SP, Hansen NJ, Israel DI, Jiang J, Kavarana MJ, Kelley MS, Kollmann CS, Li F, Lind K, Mataruse S, Medeiros PF, Messer JA, Myers P, O'Keefe H, Oliff MC, Rise CE, Satz AL, Skinner SR, Svendsen JL, Tang L, van Vloten K, Wagner RW, Yao G, Zhao B, Morgan BA.

Nat Chem Biol. 2009 Sep;5(9):647-54. doi: 10.1038/nchembio.211. Epub 2009 Aug 2. Erratum in: Nat Chem Biol. 2009 Oct;5(10):772.

PMID:
19648931
18.

Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry.

Wodicka LM, Ciceri P, Davis MI, Hunt JP, Floyd M, Salerno S, Hua XH, Ford JM, Armstrong RC, Zarrinkar PP, Treiber DK.

Chem Biol. 2010 Nov 24;17(11):1241-9. doi: 10.1016/j.chembiol.2010.09.010.

19.

Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity.

Sharlow ER, Mustata Wilson G, Close D, Leimgruber S, Tandon M, Reed RB, Shun TY, Wang QJ, Wipf P, Lazo JS.

PLoS One. 2011;6(10):e25134. doi: 10.1371/journal.pone.0025134. Epub 2011 Oct 5.

20.

Small-molecular, non-peptide, non-ATP-competitive polo-like kinase 1 (Plk1) inhibitors with a terphenyl skeleton.

Mita Y, Noguchi-Yachide T, Ishikawa M, Hashimoto Y.

Bioorg Med Chem. 2013 Feb 1;21(3):608-17. doi: 10.1016/j.bmc.2012.11.054. Epub 2012 Dec 11.

PMID:
23276450
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