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Results: 1 to 20 of 243

1.

Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes.

Ablasser A, Poeck H, Anz D, Berger M, Schlee M, Kim S, Bourquin C, Goutagny N, Jiang Z, Fitzgerald KA, Rothenfusser S, Endres S, Hartmann G, Hornung V.

J Immunol. 2009 Jun 1;182(11):6824-33. doi: 10.4049/jimmunol.0803001.

PMID:
19454678
[PubMed - indexed for MEDLINE]
Free Article
2.

T cell-independent, TLR-induced IL-12p70 production in primary human monocytes.

Bekeredjian-Ding I, Roth SI, Gilles S, Giese T, Ablasser A, Hornung V, Endres S, Hartmann G.

J Immunol. 2006 Jun 15;176(12):7438-46.

PMID:
16751389
[PubMed - indexed for MEDLINE]
Free Article
3.

Replication-dependent potent IFN-alpha induction in human plasmacytoid dendritic cells by a single-stranded RNA virus.

Hornung V, Schlender J, Guenthner-Biller M, Rothenfusser S, Endres S, Conzelmann KK, Hartmann G.

J Immunol. 2004 Nov 15;173(10):5935-43.

PMID:
15528327
[PubMed - indexed for MEDLINE]
Free Article
4.

Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8.

Gorden KB, Gorski KS, Gibson SJ, Kedl RM, Kieper WC, Qiu X, Tomai MA, Alkan SS, Vasilakos JP.

J Immunol. 2005 Feb 1;174(3):1259-68.

PMID:
15661881
[PubMed - indexed for MEDLINE]
Free Article
5.

Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses.

Forsbach A, Nemorin JG, Montino C, Müller C, Samulowitz U, Vicari AP, Jurk M, Mutwiri GK, Krieg AM, Lipford GB, Vollmer J.

J Immunol. 2008 Mar 15;180(6):3729-38.

PMID:
18322178
[PubMed - indexed for MEDLINE]
Free Article
6.

In vitro-generated viral double-stranded RNA in contrast to polyinosinic:polycytidylic acid induces interferon-alpha in human plasmacytoid dendritic cells.

Löseke S, Grage-Griebenow E, Heine H, Wagner A, Akira S, Bauer S, Bufe A.

Scand J Immunol. 2006 Apr;63(4):264-74.

PMID:
16623926
[PubMed - indexed for MEDLINE]
7.

Synthesis and immunological activities of novel Toll-like receptor 7 and 8 agonists.

Kandimalla ER, Struthers M, Bett AJ, Wisniewski T, Dubey SA, Jiang W, Precopio M, Sun Z, Wang H, Lan T, Agrawal S, Casimiro DR.

Cell Immunol. 2011;270(2):126-34. doi: 10.1016/j.cellimm.2011.03.027. Epub 2011 Apr 22.

PMID:
21570062
[PubMed - indexed for MEDLINE]
8.

TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1beta and caspase-1 in monocytes and dendritic cells.

Hurst J, Prinz N, Lorenz M, Bauer S, Chapman J, Lackner KJ, von Landenberg P.

Immunobiology. 2009;214(8):683-91. doi: 10.1016/j.imbio.2008.12.003. Epub 2009 Feb 26.

PMID:
19249118
[PubMed - indexed for MEDLINE]
9.

Human dendritic cells stimulated via TLR7 and/or TLR8 induce the sequential production of Il-10, IFN-gamma, and IL-17A by naive CD4+ T cells.

Lombardi V, Van Overtvelt L, Horiot S, Moingeon P.

J Immunol. 2009 Mar 15;182(6):3372-9. doi: 10.4049/jimmunol.0801969.

PMID:
19265114
[PubMed - indexed for MEDLINE]
Free Article
10.

Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression.

Matikainen S, Sirén J, Tissari J, Veckman V, Pirhonen J, Severa M, Sun Q, Lin R, Meri S, Uzé G, Hiscott J, Julkunen I.

J Virol. 2006 Apr;80(7):3515-22.

PMID:
16537619
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

TLR8-driven IL-12-dependent reciprocal and synergistic activation of NK cells and monocytes by immunostimulatory RNA.

Berger M, Ablasser A, Kim S, Bekeredjian-Ding I, Giese T, Endres S, Hornung V, Hartmann G.

J Immunother. 2009 Apr;32(3):262-71. doi: 10.1097/CJI.0b013e318198bd2a.

PMID:
19242374
[PubMed - indexed for MEDLINE]
12.

Dual or triple activation of TLR7, TLR8, and/or TLR9 by single-stranded oligoribonucleotides.

Forsbach A, Samulowitz U, Völp K, Hofmann HP, Noll B, Tluk S, Schmitz C, Wader T, Müller C, Podszuweit A, Lohner A, Curdt R, Uhlmann E, Vollmer J.

Nucleic Acid Ther. 2011 Dec;21(6):423-36. doi: 10.1089/nat.2011.0323.

PMID:
22196370
[PubMed - indexed for MEDLINE]
13.

CD14+ cells are required for IL-12 response in bovine blood mononuclear cells activated with Toll-like receptor (TLR) 7 and TLR8 ligands.

Buza J, Benjamin P, Zhu J, Wilson HL, Lipford G, Krieg AM, Babiuk LA, Mutwiri GK.

Vet Immunol Immunopathol. 2008 Dec 15;126(3-4):273-82. doi: 10.1016/j.vetimm.2008.08.001. Epub 2008 Aug 20.

PMID:
18789542
[PubMed - indexed for MEDLINE]
14.

Stabilized immune modulatory RNA compounds as agonists of Toll-like receptors 7 and 8.

Lan T, Kandimalla ER, Yu D, Bhagat L, Li Y, Wang D, Zhu F, Tang JX, Putta MR, Cong Y, Trombino AF, Sullivan T, Agrawal S.

Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13750-5. Epub 2007 Aug 14.

PMID:
17698957
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturation.

Larangé A, Antonios D, Pallardy M, Kerdine-Römer S.

J Leukoc Biol. 2009 Apr;85(4):673-83. doi: 10.1189/jlb.0808504. Epub 2009 Jan 21.

PMID:
19164127
[PubMed - indexed for MEDLINE]
Free Article
16.

Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration.

Boullart AC, Aarntzen EH, Verdijk P, Jacobs JF, Schuurhuis DH, Benitez-Ribas D, Schreibelt G, van de Rakt MW, Scharenborg NM, de Boer A, Kramer M, Figdor CG, Punt CJ, Adema GJ, de Vries IJ.

Cancer Immunol Immunother. 2008 Nov;57(11):1589-97. doi: 10.1007/s00262-008-0489-2. Epub 2008 Mar 6.

PMID:
18322684
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

RNA recognition via TLR7 and TLR8.

Hornung V, Barchet W, Schlee M, Hartmann G.

Handb Exp Pharmacol. 2008;(183):71-86. Review.

PMID:
18071655
[PubMed - indexed for MEDLINE]
18.

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8.

Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S, Lipford G, Wagner H, Bauer S.

Science. 2004 Mar 5;303(5663):1526-9. Epub 2004 Feb 19.

PMID:
14976262
[PubMed - indexed for MEDLINE]
Free Article
19.

Impaired cytokine response in myeloid dendritic cells in chronic hepatitis C virus infection regardless of enhanced expression of Toll-like receptors and retinoic acid inducible gene-I.

Miyazaki M, Kanto T, Inoue M, Itose I, Miyatake H, Sakakibara M, Yakushijin T, Kakita N, Hiramatsu N, Takehara T, Kasahara A, Hayashi N.

J Med Virol. 2008 Jun;80(6):980-8. doi: 10.1002/jmv.21174.

PMID:
18428149
[PubMed - indexed for MEDLINE]
20.

Oligodeoxynucleotides differentially modulate activation of TLR7 and TLR8 by imidazoquinolines.

Gorden KK, Qiu X, Battiste JJ, Wightman PP, Vasilakos JP, Alkan SS.

J Immunol. 2006 Dec 1;177(11):8164-70.

PMID:
17114492
[PubMed - indexed for MEDLINE]
Free Article

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