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Items: 1 to 20 of 151

1.

Disassembly of exon junction complexes by PYM.

Gehring NH, Lamprinaki S, Kulozik AE, Hentze MW.

Cell. 2009 May 1;137(3):536-48. doi: 10.1016/j.cell.2009.02.042.

2.

PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs.

Diem MD, Chan CC, Younis I, Dreyfuss G.

Nat Struct Mol Biol. 2007 Dec;14(12):1173-9. Epub 2007 Nov 18.

PMID:
18026120
3.

The EJC binding and dissociating activity of PYM is regulated in Drosophila.

Ghosh S, Obrdlik A, Marchand V, Ephrussi A.

PLoS Genet. 2014 Jun 26;10(6):e1004455. doi: 10.1371/journal.pgen.1004455. eCollection 2014 Jun. Erratum in: PLoS Genet. 2015 Apr;11(4):e1005157.

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The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay.

Gehring NH, Lamprinaki S, Hentze MW, Kulozik AE.

PLoS Biol. 2009 May 26;7(5):e1000120. doi: 10.1371/journal.pbio.1000120. Epub 2009 May 26.

6.

Association of the breast cancer protein MLN51 with the exon junction complex via its speckle localizer and RNA binding module.

Degot S, Le Hir H, Alpy F, Kedinger V, Stoll I, Wendling C, Seraphin B, Rio MC, Tomasetto C.

J Biol Chem. 2004 Aug 6;279(32):33702-15. Epub 2004 May 27.

7.

Exon junction complex enhances translation of spliced mRNAs at multiple steps.

Lee HC, Choe J, Chi SG, Kim YK.

Biochem Biophys Res Commun. 2009 Jul 3;384(3):334-40. doi: 10.1016/j.bbrc.2009.04.123. Epub 2009 May 3.

PMID:
19409878
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11.

eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay.

Shibuya T, Tange TØ, Sonenberg N, Moore MJ.

Nat Struct Mol Biol. 2004 Apr;11(4):346-51. Epub 2004 Mar 21.

PMID:
15034551
12.

Introns play an essential role in splicing-dependent formation of the exon junction complex.

Ideue T, Sasaki YT, Hagiwara M, Hirose T.

Genes Dev. 2007 Aug 15;21(16):1993-8. Epub 2007 Aug 3.

13.

Phosphorylation of Y14 modulates its interaction with proteins involved in mRNA metabolism and influences its methylation.

Hsu IaW, Hsu M, Li C, Chuang TW, Lin RI, Tarn WY.

J Biol Chem. 2005 Oct 14;280(41):34507-12. Epub 2005 Aug 12.

14.

Structure of the Y14-Magoh core of the exon junction complex.

Lau CK, Diem MD, Dreyfuss G, Van Duyne GD.

Curr Biol. 2003 May 27;13(11):933-41.

15.

The exon junction complex differentially marks spliced junctions.

Saulière J, Haque N, Harms S, Barbosa I, Blanchette M, Le Hir H.

Nat Struct Mol Biol. 2010 Oct;17(10):1269-71. doi: 10.1038/nsmb.1890. Epub 2010 Sep 5.

PMID:
20818392
16.

Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements.

Gehring NH, Kunz JB, Neu-Yilik G, Breit S, Viegas MH, Hentze MW, Kulozik AE.

Mol Cell. 2005 Oct 7;20(1):65-75.

17.

Exon junction complexes mediate the enhancing effect of splicing on mRNA expression.

Wiegand HL, Lu S, Cullen BR.

Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11327-32. Epub 2003 Sep 12.

18.

Human spliceosomal protein CWC22 plays a role in coupling splicing to exon junction complex deposition and nonsense-mediated decay.

Alexandrov A, Colognori D, Shu MD, Steitz JA.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21313-8. doi: 10.1073/pnas.1219725110. Epub 2012 Dec 10.

19.

Kaposi's sarcoma-associated herpesvirus ORF57 protein interacts with PYM to enhance translation of viral intronless mRNAs.

Boyne JR, Jackson BR, Taylor A, Macnab SA, Whitehouse A.

EMBO J. 2010 Jun 2;29(11):1851-64. doi: 10.1038/emboj.2010.77. Epub 2010 Apr 30.

20.
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