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Items: 1 to 20 of 126

1.

Colocalization of ghrelin O-acyltransferase and ghrelin in gastric mucosal cells.

Sakata I, Yang J, Lee CE, Osborne-Lawrence S, Rovinsky SA, Elmquist JK, Zigman JM.

Am J Physiol Endocrinol Metab. 2009 Jul;297(1):E134-41. doi: 10.1152/ajpendo.90859.2008. Epub 2009 Apr 28.

2.

Differential distribution of ghrelin-O-acyltransferase (GOAT) immunoreactive cells in the mouse and rat gastric oxyntic mucosa.

Stengel A, Goebel M, Wang L, Taché Y, Sachs G, Lambrecht NW.

Biochem Biophys Res Commun. 2010 Jan 29;392(1):67-71. doi: 10.1016/j.bbrc.2009.12.169. Epub 2010 Jan 7.

3.

Ghrelin octanoylation mediated by an orphan lipid transferase.

Gutierrez JA, Solenberg PJ, Perkins DR, Willency JA, Knierman MD, Jin Z, Witcher DR, Luo S, Onyia JE, Hale JE.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6320-5. doi: 10.1073/pnas.0800708105. Epub 2008 Apr 28.

4.

Discovery of ghrelin o-acyltransferase.

Mohan H, Unniappan S.

Endocr Dev. 2013;25:16-24. doi: 10.1159/000346039. Epub 2013 Apr 25.

PMID:
23652388
5.

GOAT: the master switch for the ghrelin system?

Romero A, Kirchner H, Heppner K, Pfluger PT, Tschöp MH, Nogueiras R.

Eur J Endocrinol. 2010 Jul;163(1):1-8. doi: 10.1530/EJE-10-0099. Epub 2010 Apr 26. Review.

6.

The expression of ghrelin O-acyltransferase (GOAT) in human tissues.

Lim CT, Kola B, Grossman A, Korbonits M.

Endocr J. 2011;58(8):707-10. Epub 2011 Jun 4.

7.

Influence of chronic undernutrition and leptin on GOAT mRNA levels in rat stomach mucosa.

González CR, Vázquez MJ, López M, Diéguez C.

J Mol Endocrinol. 2008 Dec;41(6):415-21. doi: 10.1677/JME-08-0102. Epub 2008 Oct 3.

8.

Metabolic regulation of ghrelin O-acyl transferase (GOAT) expression in the mouse hypothalamus, pituitary, and stomach.

Gahete MD, Córdoba-Chacón J, Salvatori R, Castaño JP, Kineman RD, Luque RM.

Mol Cell Endocrinol. 2010 Apr 12;317(1-2):154-60. doi: 10.1016/j.mce.2009.12.023. Epub 2009 Dec 23.

9.

From ghrelin to ghrelin's O-acyl transferase.

Gutierrez JA, Willency JA, Knierman MD, Coskun T, Solenberg PJ, Perkins DR, Higgs RE, Hale JE.

Methods Enzymol. 2012;514:129-46. doi: 10.1016/B978-0-12-381272-8.00009-X.

PMID:
22975051
10.

Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone.

Yang J, Brown MS, Liang G, Grishin NV, Goldstein JL.

Cell. 2008 Feb 8;132(3):387-96. doi: 10.1016/j.cell.2008.01.017.

11.

Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitro by ghrelin.

Seim I, Jeffery PL, de Amorim L, Walpole CM, Fung J, Whiteside EJ, Lourie R, Herington AC, Chopin LK.

Reprod Biol Endocrinol. 2013 Jul 23;11:70. doi: 10.1186/1477-7827-11-70.

12.

From GH to Billy Ghrelin.

Smith RG.

Cell Metab. 2009 Aug;10(2):82-3. doi: 10.1016/j.cmet.2009.07.009.

13.

Mouse ghrelin-O-acyltransferase (GOAT) plays a critical role in bile acid reabsorption.

Kang K, Schmahl J, Lee JM, Garcia K, Patil K, Chen A, Keene M, Murphy A, Sleeman MW.

FASEB J. 2012 Jan;26(1):259-71. doi: 10.1096/fj.11-191460. Epub 2011 Sep 29.

14.

Enzymatic characterization of GOAT, ghrelin O-acyltransferase.

Ohgusu H, Takahashi T, Kojima M.

Methods Enzymol. 2012;514:147-63. doi: 10.1016/B978-0-12-381272-8.00010-6.

PMID:
22975052
15.

Structure-activity analysis of human ghrelin O-acyltransferase reveals chemical determinants of ghrelin selectivity and acyl group recognition.

Darling JE, Zhao F, Loftus RJ, Patton LM, Gibbs RA, Hougland JL.

Biochemistry. 2015 Feb 3;54(4):1100-10. doi: 10.1021/bi5010359. Epub 2015 Jan 21.

PMID:
25562443
16.

Architectural organization of the metabolic regulatory enzyme ghrelin O-acyltransferase.

Taylor MS, Ruch TR, Hsiao PY, Hwang Y, Zhang P, Dai L, Huang CR, Berndsen CE, Kim MS, Pandey A, Wolberger C, Marmorstein R, Machamer C, Boeke JD, Cole PA.

J Biol Chem. 2013 Nov 8;288(45):32211-28. doi: 10.1074/jbc.M113.510313. Epub 2013 Sep 17.

17.

Ghrelin acylation and metabolic control.

Al Massadi O, Tschöp MH, Tong J.

Peptides. 2011 Nov;32(11):2301-8. doi: 10.1016/j.peptides.2011.08.020. Epub 2011 Aug 27. Review.

PMID:
21893140
18.

GOAT induced ghrelin acylation regulates hedonic feeding.

Davis JF, Perello M, Choi DL, Magrisso IJ, Kirchner H, Pfluger PT, Tschoep M, Zigman JM, Benoit SC.

Horm Behav. 2012 Nov;62(5):598-604. doi: 10.1016/j.yhbeh.2012.08.009. Epub 2012 Sep 8.

19.

Plasma ghrelin isoforms and gastric ghrelin O-acyltransferase expression are influenced by Helicobacter pylori status.

Ando T, Mizuno S, Ishida T, Kondo Y, Miki I, Yoshida M, Azuma T, Ishikawa T, Takagi T, Yagi N, Kokura S, Naito Y, Yoshikawa T, Asakawa A, Inui A.

Nutrition. 2012 Oct;28(10):967-72. doi: 10.1016/j.nut.2011.11.023. Epub 2012 Apr 6.

PMID:
22483414
20.

Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor.

Barnett BP, Hwang Y, Taylor MS, Kirchner H, Pfluger PT, Bernard V, Lin YY, Bowers EM, Mukherjee C, Song WJ, Longo PA, Leahy DJ, Hussain MA, Tschöp MH, Boeke JD, Cole PA.

Science. 2010 Dec 17;330(6011):1689-92. doi: 10.1126/science.1196154. Epub 2010 Nov 18.

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