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Results: 1 to 20 of 60

1.

The transmembrane src substrate Trask is an epithelial protein that signals during anchorage deprivation.

Spassov DS, Baehner FL, Wong CH, McDonough S, Moasser MM.

Am J Pathol. 2009 May;174(5):1756-65. doi: 10.2353/ajpath.2009.080890. Epub 2009 Apr 6.

PMID:
19349359
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Trask phosphorylation defines the reverse mode of a phosphotyrosine signaling switch that underlies cell anchorage state.

Spassov DS, Wong CH, Moasser MM.

Cell Cycle. 2011 Apr 15;10(8):1225-32. Epub 2011 Apr 15.

PMID:
21490433
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Phosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers.

Wong CH, Baehner FL, Spassov DS, Ahuja D, Wang D, Hann B, Blair J, Shokat K, Welm AL, Moasser MM.

Clin Cancer Res. 2009 Apr 1;15(7):2311-22. doi: 10.1158/1078-0432.CCR-08-2533. Epub 2009 Mar 24.

PMID:
19318475
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Phosphorylation of Trask by Src kinases inhibits integrin clustering and functions in exclusion with focal adhesion signaling.

Spassov DS, Wong CH, Sergina N, Ahuja D, Fried M, Sheppard D, Moasser MM.

Mol Cell Biol. 2011 Feb;31(4):766-82. doi: 10.1128/MCB.00841-10. Epub 2010 Dec 28.

PMID:
21189288
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Adhesion signaling by a novel mitotic substrate of src kinases.

Bhatt AS, Erdjument-Bromage H, Tempst P, Craik CS, Moasser MM.

Oncogene. 2005 Aug 11;24(34):5333-43.

PMID:
16007225
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Src SH3/2 domain-mediated peripheral accumulation of Src and phospho-myosin is linked to deregulation of E-cadherin and the epithelial-mesenchymal transition.

Avizienyte E, Fincham VJ, Brunton VG, Frame MC.

Mol Biol Cell. 2004 Jun;15(6):2794-803. Epub 2004 Apr 9.

PMID:
15075377
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation.

Miyazawa Y, Uekita T, Hiraoka N, Fujii S, Kosuge T, Kanai Y, Nojima Y, Sakai R.

Cancer Res. 2010 Jun 15;70(12):5136-46. doi: 10.1158/0008-5472.CAN-10-0220. Epub 2010 May 25.

PMID:
20501830
[PubMed - indexed for MEDLINE]
Free Article
8.

A tumor-suppressing function in the epithelial adhesion protein Trask.

Spassov DS, Wong CH, Harris G, McDonough S, Phojanakong P, Wang D, Hann B, Bazarov AV, Yaswen P, Khanafshar E, Moasser MM.

Oncogene. 2012 Jan 26;31(4):419-31. doi: 10.1038/onc.2011.246. Epub 2011 Jun 27.

PMID:
21706059
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The structural features of Trask that mediate its anti-adhesive functions.

Spassov DS, Ahuja D, Wong CH, Moasser MM.

PLoS One. 2011 Apr 29;6(4):e19154. doi: 10.1371/journal.pone.0019154.

PMID:
21559459
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

c-Src-mediated epithelial cell migration and invasion regulated by PDZ binding site.

Baumgartner M, Radziwill G, Lorger M, Weiss A, Moelling K.

Mol Cell Biol. 2008 Jan;28(2):642-55. Epub 2007 Nov 26.

PMID:
18039857
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

Cobb BS, Schaller MD, Leu TH, Parsons JT.

Mol Cell Biol. 1994 Jan;14(1):147-55.

PMID:
7505391
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

ESX induces transformation and functional epithelial to mesenchymal transition in MCF-12A mammary epithelial cells.

Schedin PJ, Eckel-Mahan KL, McDaniel SM, Prescott JD, Brodsky KS, Tentler JJ, Gutierrez-Hartmann A.

Oncogene. 2004 Mar 4;23(9):1766-79.

PMID:
14767472
[PubMed - indexed for MEDLINE]
13.

Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases.

Schaller MD, Hildebrand JD, Parsons JT.

Mol Biol Cell. 1999 Oct;10(10):3489-505.

PMID:
10512882
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Spectrin redistributes to the cytosol and is phosphorylated during mitosis in cultured cells.

Fowler VM, Adam EJ.

J Cell Biol. 1992 Dec;119(6):1559-72.

PMID:
1469048
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Modulation of voltage-dependent Ca2+ channels in rabbit colonic smooth muscle cells by c-Src and focal adhesion kinase.

Hu XQ, Singh N, Mukhopadhyay D, Akbarali HI.

J Biol Chem. 1998 Feb 27;273(9):5337-42.

PMID:
9478993
[PubMed - indexed for MEDLINE]
Free Article
16.

The role of membrane microdomains in transmembrane signaling through the epithelial glycoprotein Gp140/CDCP1.

Alvares SM, Dunn CA, Brown TA, Wayner EE, Carter WG.

Biochim Biophys Acta. 2008 Mar;1780(3):486-96. doi: 10.1016/j.bbagen.2008.01.010. Epub 2008 Jan 26.

PMID:
18269919
[PubMed - indexed for MEDLINE]
17.

CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells.

Muenzner P, Rohde M, Kneitz S, Hauck CR.

J Cell Biol. 2005 Aug 29;170(5):825-36. Epub 2005 Aug 22.

PMID:
16115956
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration.

Hu H, Bliss JM, Wang Y, Colicelli J.

Curr Biol. 2005 May 10;15(9):815-23.

PMID:
15886098
[PubMed - indexed for MEDLINE]
Free Article
20.

The chemopreventive bioflavonoid apigenin inhibits prostate cancer cell motility through the focal adhesion kinase/Src signaling mechanism.

Franzen CA, Amargo E, Todorović V, Desai BV, Huda S, Mirzoeva S, Chiu K, Grzybowski BA, Chew TL, Green KJ, Pelling JC.

Cancer Prev Res (Phila). 2009 Sep;2(9):830-41. doi: 10.1158/1940-6207.CAPR-09-0066. Epub 2009 Sep 8.

PMID:
19737984
[PubMed - indexed for MEDLINE]
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