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Results: 1 to 20 of 433

1.

p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling.

Abe Y, Yoon SO, Kubota K, Mendoza MC, Gygi SP, Blenis J.

J Biol Chem. 2009 May 29;284(22):14939-48. doi: 10.1074/jbc.M900097200. Epub 2009 Mar 30.

PMID:
19332537
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase.

Roux PP, Ballif BA, Anjum R, Gygi SP, Blenis J.

Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13489-94. Epub 2004 Sep 1.

PMID:
15342917
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover.

Mieulet V, Roceri M, Espeillac C, Sotiropoulos A, Ohanna M, Oorschot V, Klumperman J, Sandri M, Pende M.

Am J Physiol Cell Physiol. 2007 Aug;293(2):C712-22. Epub 2007 May 9.

PMID:
17494629
[PubMed - indexed for MEDLINE]
Free Article
4.

RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.

Roux PP, Shahbazian D, Vu H, Holz MK, Cohen MS, Taunton J, Sonenberg N, Blenis J.

J Biol Chem. 2007 May 11;282(19):14056-64. Epub 2007 Mar 14.

PMID:
17360704
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The mammalian target of rapamycin-p70 ribosomal S6 kinase but not phosphatidylinositol 3-kinase-Akt signaling is responsible for fibroblast growth factor-9-induced cell proliferation.

Wing LY, Chen HM, Chuang PC, Wu MH, Tsai SJ.

J Biol Chem. 2005 May 20;280(20):19937-47. Epub 2005 Mar 10.

PMID:
15760907
[PubMed - indexed for MEDLINE]
Free Article
7.

P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation.

Li P, Goto H, Kasahara K, Matsuyama M, Wang Z, Yatabe Y, Kiyono T, Inagaki M.

Mol Biol Cell. 2012 Apr;23(8):1582-92. doi: 10.1091/mbc.E11-10-0883. Epub 2012 Feb 22.

PMID:
22357623
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity.

Roux PP, Richards SA, Blenis J.

Mol Cell Biol. 2003 Jul;23(14):4796-804.

PMID:
12832467
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation.

Carrière A, Cargnello M, Julien LA, Gao H, Bonneil E, Thibault P, Roux PP.

Curr Biol. 2008 Sep 9;18(17):1269-77. doi: 10.1016/j.cub.2008.07.078. Epub 2008 Aug 21.

PMID:
18722121
[PubMed - indexed for MEDLINE]
Free Article
10.

The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity.

Shahbazian D, Roux PP, Mieulet V, Cohen MS, Raught B, Taunton J, Hershey JW, Blenis J, Pende M, Sonenberg N.

EMBO J. 2006 Jun 21;25(12):2781-91. Epub 2006 Jun 8.

PMID:
16763566
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

14-3-3beta is a p90 ribosomal S6 kinase (RSK) isoform 1-binding protein that negatively regulates RSK kinase activity.

Cavet ME, Lehoux S, Berk BC.

J Biol Chem. 2003 May 16;278(20):18376-83. Epub 2003 Mar 4.

PMID:
12618428
[PubMed - indexed for MEDLINE]
Free Article
13.

Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases.

Moritz A, Li Y, Guo A, Villén J, Wang Y, MacNeill J, Kornhauser J, Sprott K, Zhou J, Possemato A, Ren JM, Hornbeck P, Cantley LC, Gygi SP, Rush J, Comb MJ.

Sci Signal. 2010 Aug 24;3(136):ra64. doi: 10.1126/scisignal.2000998.

PMID:
20736484
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1.

Phin S, Kupferwasser D, Lam J, Lee-Fruman KK.

Biochem J. 2003 Jul 15;373(Pt 2):583-91.

PMID:
12713446
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes.

Pham PT, Heydrick SJ, Fox HL, Kimball SR, Jefferson LS Jr, Lynch CJ.

J Cell Biochem. 2000 Sep 7;79(3):427-41.

PMID:
10972980
[PubMed - indexed for MEDLINE]
16.

In vivo role of the phosphate groove of PDK1 defined by knockin mutation.

Collins BJ, Deak M, Murray-Tait V, Storey KG, Alessi DR.

J Cell Sci. 2005 Nov 1;118(Pt 21):5023-34. Epub 2005 Oct 11.

PMID:
16219676
[PubMed - indexed for MEDLINE]
Free Article
17.

Glucagon represses signaling through the mammalian target of rapamycin in rat liver by activating AMP-activated protein kinase.

Kimball SR, Siegfried BA, Jefferson LS.

J Biol Chem. 2004 Dec 24;279(52):54103-9. Epub 2004 Oct 19.

PMID:
15494402
[PubMed - indexed for MEDLINE]
Free Article
18.

Inhibition of insulin signaling and adipogenesis by rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1.

El-Chaâr D, Gagnon A, Sorisky A.

Int J Obes Relat Metab Disord. 2004 Feb;28(2):191-8.

PMID:
14970836
[PubMed - indexed for MEDLINE]
19.

Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target of rapamycin, and p70 S6 kinase signaling pathways.

Gerasimovskaya EV, Tucker DA, Weiser-Evans M, Wenzlau JM, Klemm DJ, Banks M, Stenmark KR.

J Biol Chem. 2005 Jan 21;280(3):1838-48. Epub 2004 Nov 1.

PMID:
15522879
[PubMed - indexed for MEDLINE]
Free Article
20.

G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.

Gao N, Flynn DC, Zhang Z, Zhong XS, Walker V, Liu KJ, Shi X, Jiang BH.

Am J Physiol Cell Physiol. 2004 Aug;287(2):C281-91. Epub 2004 Mar 17.

PMID:
15028555
[PubMed - indexed for MEDLINE]
Free Article
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