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Items: 1 to 20 of 162

1.

Long-term rapamycin therapy in the Han:SPRD rat model of polycystic kidney disease (PKD).

Zafar I, Belibi FA, He Z, Edelstein CL.

Nephrol Dial Transplant. 2009 Aug;24(8):2349-53. doi: 10.1093/ndt/gfp129. Epub 2009 Mar 25.

2.

Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD).

Wahl PR, Serra AL, Le Hir M, Molle KD, Hall MN, Wüthrich RP.

Nephrol Dial Transplant. 2006 Mar;21(3):598-604. Epub 2005 Oct 12.

3.

Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease.

Tao Y, Kim J, Schrier RW, Edelstein CL.

J Am Soc Nephrol. 2005 Jan;16(1):46-51. Epub 2004 Nov 24.

4.

Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease.

Wu M, Wahl PR, Le Hir M, Wackerle-Men Y, Wuthrich RP, Serra AL.

Kidney Blood Press Res. 2007;30(4):253-9. Epub 2007 Jun 27.

PMID:
17596700
5.

A new in vitro bioassay for cyst formation by renal cells from an autosomal dominant rat model of polycystic kidney disease.

Pey R, Bach J, Schieren G, Gretz N, Hafner M.

In Vitro Cell Dev Biol Anim. 1999 Nov-Dec;35(10):571-9.

PMID:
10614866
6.

Mycophenolate mofetil versus Rapamycin in Han: SPRD rats with Polycystic Kidney Disease.

Zhang T, Wang L, Xiong X, Mao Z, Wang L, Mei C.

Biol Res. 2009;42(4):437-44. doi: /S0716-97602009000400005. Epub 2010 Jan 29.

7.

Sirolimus ameliorates the enhanced expression of metalloproteinases in a rat model of autosomal dominant polycystic kidney disease.

Berthier CC, Wahl PR, Le Hir M, Marti HP, Wagner U, Rehrauer H, Wüthrich RP, Serra AL.

Nephrol Dial Transplant. 2008 Mar;23(3):880-9. Epub 2007 Nov 27.

8.

The effect of paclitaxel on the progression of polycystic kidney disease in rodents.

Martinez JR, Cowley BD, Gattone VH 2nd, Nagao S, Yamaguchi T, Kaneta S, Takahashi H, Grantham JJ.

Am J Kidney Dis. 1997 Mar;29(3):435-44.

PMID:
9041221
9.

Pulse mTOR inhibitor treatment effectively controls cyst growth but leads to severe parenchymal and glomerular hypertrophy in rat polycystic kidney disease.

Wu M, Arcaro A, Varga Z, Vogetseder A, Le Hir M, Wüthrich RP, Serra AL.

Am J Physiol Renal Physiol. 2009 Dec;297(6):F1597-605. doi: 10.1152/ajprenal.00430.2009. Epub 2009 Sep 23.

10.

mTORC1/2 and rapamycin in female Han:SPRD rats with polycystic kidney disease.

Belibi F, Ravichandran K, Zafar I, He Z, Edelstein CL.

Am J Physiol Renal Physiol. 2011 Jan;300(1):F236-44. doi: 10.1152/ajprenal.00129.2010. Epub 2010 Oct 13.

11.

Methylprednisolone retards the progression of inherited polycystic kidney disease in rodents.

Gattone VH 2nd, Cowley BD Jr, Barash BD, Nagao S, Takahashi H, Yamaguchi T, Grantham JJ.

Am J Kidney Dis. 1995 Feb;25(2):302-13.

PMID:
7847359
12.
13.
14.

Hypertension and renal injury in experimental polycystic kidney disease.

Kennefick TM, Al-Nimri MA, Oyama TT, Thompson MM, Kelly FJ, Chapman JG, Anderson S.

Kidney Int. 1999 Dec;56(6):2181-90.

PMID:
10594794
15.

Sirolimus attenuates disease progression in an orthologous mouse model of human autosomal dominant polycystic kidney disease.

Zafar I, Ravichandran K, Belibi FA, Doctor RB, Edelstein CL.

Kidney Int. 2010 Oct;78(8):754-61. doi: 10.1038/ki.2010.250. Epub 2010 Aug 4.

PMID:
20686448
16.

Caspase inhibition reduces tubular apoptosis and proliferation and slows disease progression in polycystic kidney disease.

Tao Y, Kim J, Faubel S, Wu JC, Falk SA, Schrier RW, Edelstein CL.

Proc Natl Acad Sci U S A. 2005 May 10;102(19):6954-9. Epub 2005 Apr 29.

17.

EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats.

Torres VE, Sweeney WE Jr, Wang X, Qian Q, Harris PC, Frost P, Avner ED.

Kidney Int. 2003 Nov;64(5):1573-9.

PMID:
14531789
18.

Progression of renal failure in the Han: SPRD polycystic kidney rat.

Zeier M, Pohlmeyer G, Deerberg F, Schönherr R, Ritz E.

Nephrol Dial Transplant. 1994;9(12):1734-9.

PMID:
7708256
19.

Dietary soy protein effects on disease and IGF-I in male and female Han:SPRD-cy rats.

Aukema HM, Housini I.

Kidney Int. 2001 Jan;59(1):52-61.

PMID:
11135057
20.

Chronic caffeine consumption exacerbates hypertension in rats with polycystic kidney disease.

Tanner GA, Tanner JA.

Am J Kidney Dis. 2001 Nov;38(5):1089-95.

PMID:
11684564
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