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Items: 1 to 20 of 406

1.

Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro.

Mukhopadhyay P, Rajesh M, Bátkai S, Kashiwaya Y, Haskó G, Liaudet L, Szabó C, Pacher P.

Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1466-83. doi: 10.1152/ajpheart.00795.2008. Epub 2009 Mar 13.

2.

Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction.

Pacher P, Liaudet L, Bai P, Mabley JG, Kaminski PM, Virág L, Deb A, Szabó E, Ungvári Z, Wolin MS, Groves JT, Szabó C.

Circulation. 2003 Feb 18;107(6):896-904.

3.

Role of redox signaling and poly (adenosine diphosphate-ribose) polymerase activation in vascular smooth muscle cell growth inhibition by nitric oxide and peroxynitrite.

Huang J, Lin SC, Nadershahi A, Watts SW, Sarkar R.

J Vasc Surg. 2008 Mar;47(3):599-607. doi: 10.1016/j.jvs.2007.11.006.

4.

Ouabain increases iNOS-dependent nitric oxide generation which contributes to the hypertrophic effect of the glycoside: possible role of peroxynitrite formation.

Gan XT, Hunter JC, Huang C, Xue J, Rajapurohitam V, Javadov S, Karmazyn M.

Mol Cell Biochem. 2012 Apr;363(1-2):323-33. doi: 10.1007/s11010-011-1185-7. Epub 2011 Dec 10.

PMID:
22160804
5.

Differential roles of nitric oxide synthase isozymes in cardiotoxicity and mortality following chronic doxorubicin treatment in mice.

Deng S, Kruger A, Schmidt A, Metzger A, Yan T, Gödtel-Armbrust U, Hasenfuss G, Brunner F, Wojnowski L.

Naunyn Schmiedebergs Arch Pharmacol. 2009 Jul;380(1):25-34. doi: 10.1007/s00210-009-0407-y. Epub 2009 Mar 24.

6.

Cannabidiol Protects against Doxorubicin-Induced Cardiomyopathy by Modulating Mitochondrial Function and Biogenesis.

Hao E, Mukhopadhyay P, Cao Z, Erdélyi K, Holovac E, Liaudet L, Lee WS, Haskó G, Mechoulam R, Pacher P.

Mol Med. 2015 Jan 6;21:38-45. doi: 10.2119/molmed.2014.00261.

7.

Cardiac-targeted expression of soluble fas attenuates doxorubicin-induced cardiotoxicity in mice.

Niu J, Azfer A, Wang K, Wang X, Kolattukudy PE.

J Pharmacol Exp Ther. 2009 Mar;328(3):740-8. doi: 10.1124/jpet.108.146423. Epub 2008 Dec 9.

8.

Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of oxidative/nitrative stress.

Tao L, Gao E, Jiao X, Yuan Y, Li S, Christopher TA, Lopez BL, Koch W, Chan L, Goldstein BJ, Ma XL.

Circulation. 2007 Mar 20;115(11):1408-16. Epub 2007 Mar 5.

9.

Cytoprotective effect of anthocyanins against doxorubicin-induced toxicity in H9c2 cardiomyocytes in relation to their antioxidant activities.

Choi EH, Chang HJ, Cho JY, Chun HS.

Food Chem Toxicol. 2007 Oct;45(10):1873-81. Epub 2007 Apr 21.

PMID:
17524543
10.

Rac1 signalling mediates doxorubicin-induced cardiotoxicity through both reactive oxygen species-dependent and -independent pathways.

Ma J, Wang Y, Zheng D, Wei M, Xu H, Peng T.

Cardiovasc Res. 2013 Jan 1;97(1):77-87. doi: 10.1093/cvr/cvs309. Epub 2012 Oct 1.

11.

Role of HMGB1 in doxorubicin-induced myocardial apoptosis and its regulation pathway.

Yao Y, Xu X, Zhang G, Zhang Y, Qian W, Rui T.

Basic Res Cardiol. 2012 May;107(3):267. doi: 10.1007/s00395-012-0267-3. Epub 2012 Apr 17.

PMID:
22527657
12.
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14.

Protein tyrosine nitration and poly(ADP-ribose) polymerase activation in N-methyl-N-nitro-N-nitrosoguanidine-treated thymocytes: implication for cytotoxicity.

Bai P, Hegedus C, Erdélyi K, Szabó E, Bakondi E, Gergely S, Szabó C, Virág L.

Toxicol Lett. 2007 May 15;170(3):203-13. Epub 2007 Mar 14.

PMID:
17428624
15.

Over-expression of calpastatin aggravates cardiotoxicity induced by doxorubicin.

Wang Y, Zheng D, Wei M, Ma J, Yu Y, Chen R, Lacefield JC, Xu H, Peng T.

Cardiovasc Res. 2013 Jun 1;98(3):381-90. doi: 10.1093/cvr/cvt048. Epub 2013 Mar 1.

16.

Activation of NAD(P)H oxidases by thromboxane A2 receptor uncouples endothelial nitric oxide synthase.

Zhang M, Song P, Xu J, Zou MH.

Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):125-32. doi: 10.1161/ATVBAHA.110.207712. Epub 2010 Oct 14.

17.

iNOS-derived NO and nox2-derived superoxide confer tolerance to excitotoxic brain injury through peroxynitrite.

Kawano T, Kunz A, Abe T, Girouard H, Anrather J, Zhou P, Iadecola C.

J Cereb Blood Flow Metab. 2007 Aug;27(8):1453-62. Epub 2007 Feb 7.

18.

Role of iNOS and peroxynitrite-matrix metalloproteinase-2 signaling in myocardial late preconditioning in rats.

Bencsik P, Kupai K, Giricz Z, Görbe A, Pipis J, Murlasits Z, Kocsis GF, Varga-Orvos Z, Puskás LG, Csonka C, Csont T, Ferdinandy P.

Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H512-8. doi: 10.1152/ajpheart.00052.2010. Epub 2010 Jun 11.

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20.

Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction.

Doerries C, Grote K, Hilfiker-Kleiner D, Luchtefeld M, Schaefer A, Holland SM, Sorrentino S, Manes C, Schieffer B, Drexler H, Landmesser U.

Circ Res. 2007 Mar 30;100(6):894-903. Epub 2007 Mar 1.

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