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Results: 1 to 20 of 122

Similar articles for PubMed (Select 19223867)

1.

Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element.

Hanawa H, Yamamoto M, Zhao H, Shimada T, Persons DA.

Mol Ther. 2009 Apr;17(4):667-74. doi: 10.1038/mt.2009.1. Epub 2009 Feb 17.

2.

Chicken HS4 insulators have minimal barrier function among progeny of human hematopoietic cells transduced with an HIV1-based lentiviral vector.

Uchida N, Washington KN, Lap CJ, Hsieh MM, Tisdale JF.

Mol Ther. 2011 Jan;19(1):133-9. doi: 10.1038/mt.2010.218. Epub 2010 Oct 12.

3.

A chimeric HS4-SAR insulator (IS2) that prevents silencing and enhances expression of lentiviral vectors in pluripotent stem cells.

Benabdellah K, Gutierrez-Guerrero A, Cobo M, Muñoz P, Martín F.

PLoS One. 2014 Jan 6;9(1):e84268. doi: 10.1371/journal.pone.0084268. eCollection 2014.

4.

Gene specificity of suppression of transgene-mediated insertional transcriptional activation by the chicken HS4 insulator.

Desprat R, Bouhassira EE.

PLoS One. 2009 Jun 18;4(6):e5956. doi: 10.1371/journal.pone.0005956.

5.

Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants.

Nielsen TT, Jakobsson J, Rosenqvist N, Lundberg C.

BMC Biotechnol. 2009 Feb 24;9:13. doi: 10.1186/1472-6750-9-13.

6.
8.

The chicken hypersensitivity site 4 core insulator blocks promoter interference in lentiviral vectors.

Uchida N, Hanawa H, Yamamoto M, Shimada T.

Hum Gene Ther Methods. 2013 Apr;24(2):117-24. doi: 10.1089/hgtb.2012.152.

9.

Gene Therapy for beta-thalassemia.

Malik P, Arumugam PI.

Hematology Am Soc Hematol Educ Program. 2005:45-50.

10.

Tight control of transgene expression by lentivirus vectors containing second-generation tetracycline-responsive promoters.

Pluta K, Luce MJ, Bao L, Agha-Mohammadi S, Reiser J.

J Gene Med. 2005 Jun;7(6):803-17.

PMID:
15655804
11.

Genotoxic potential of lineage-specific lentivirus vectors carrying the beta-globin locus control region.

Arumugam PI, Higashimoto T, Urbinati F, Modlich U, Nestheide S, Xia P, Fox C, Corsinotti A, Baum C, Malik P.

Mol Ther. 2009 Nov;17(11):1929-37. doi: 10.1038/mt.2009.183. Epub 2009 Aug 25.

12.

Suppression of clonal dominance in cultured human lymphoid cells by addition of the cHS4 insulator to a lentiviral vector.

Evans-Galea MV, Wielgosz MM, Hanawa H, Srivastava DK, Nienhuis AW.

Mol Ther. 2007 Apr;15(4):801-9. Epub 2007 Feb 13.

PMID:
17299406
13.

Improved human beta-globin expression from self-inactivating lentiviral vectors carrying the chicken hypersensitive site-4 (cHS4) insulator element.

Arumugam PI, Scholes J, Perelman N, Xia P, Yee JK, Malik P.

Mol Ther. 2007 Oct;15(10):1863-71. Epub 2007 Jul 10.

PMID:
17622240
14.

3' self-inactivating long terminal repeat inserts for the modulation of transgene expression from lentiviral vectors.

Manic G, Maurin-Marlin A, Galluzzi L, Subra F, Mouscadet JF, Bury-Moné S.

Hum Gene Ther Methods. 2012 Apr;23(2):84-97. doi: 10.1089/hgtb.2011.154. Epub 2012 Mar 28.

PMID:
22456436
15.

Sea urchin insulator protects lentiviral vector from silencing by maintaining active chromatin structure.

Hino S, Fan J, Taguwa S, Akasaka K, Matsuoka M.

Gene Ther. 2004 May;11(10):819-28.

PMID:
14985785
17.

Extended core sequences from the cHS4 insulator are necessary for protecting retroviral vectors from silencing position effects.

Aker M, Tubb J, Groth AC, Bukovsky AA, Bell AC, Felsenfeld G, Kiem HP, Stamatoyannopoulos G, Emery DW.

Hum Gene Ther. 2007 Apr;18(4):333-43.

PMID:
17411365
18.

The 3' region of the chicken hypersensitive site-4 insulator has properties similar to its core and is required for full insulator activity.

Arumugam PI, Urbinati F, Velu CS, Higashimoto T, Grimes HL, Malik P.

PLoS One. 2009 Sep 10;4(9):e6995. doi: 10.1371/journal.pone.0006995.

19.

Mechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3'LTR.

Urbinati F, Arumugam P, Higashimoto T, Perumbeti A, Mitts K, Xia P, Malik P.

Mol Ther. 2009 Sep;17(9):1527-36. doi: 10.1038/mt.2009.89. Epub 2009 Apr 21.

20.

Transcriptional targeting of lentiviral vectors by long terminal repeat enhancer replacement.

Lotti F, Menguzzato E, Rossi C, Naldini L, Ailles L, Mavilio F, Ferrari G.

J Virol. 2002 Apr;76(8):3996-4007.

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