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Results: 1 to 20 of 96

Similar articles for PubMed (Select 19191557)

1.

Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus.

Song Y, Lin FY, Yin F, Hensler M, Rodrígues Poveda CA, Mukkamala D, Cao R, Wang H, Morita CT, González Pacanowska D, Nizet V, Oldfield E.

J Med Chem. 2009 Feb 26;52(4):976-88. doi: 10.1021/jm801023u.

2.

Structural and functional analysis of Bacillus subtilis YisP reveals a role of its product in biofilm production.

Feng X, Hu Y, Zheng Y, Zhu W, Li K, Huang CH, Ko TP, Ren F, Chan HC, Nega M, Bogue S, López D, Kolter R, Götz F, Guo RT, Oldfield E.

Chem Biol. 2014 Nov 20;21(11):1557-63. doi: 10.1016/j.chembiol.2014.08.018. Epub 2014 Oct 9.

PMID:
25308276
3.

Directed evolution of squalene synthase for dehydrosqualene biosynthesis.

Furubayashi M, Li L, Katabami A, Saito K, Umeno D.

FEBS Lett. 2014 Sep 17;588(18):3375-81. doi: 10.1016/j.febslet.2014.07.028. Epub 2014 Aug 2.

PMID:
25093296
4.

Construction of carotenoid biosynthetic pathways using squalene synthase.

Furubayashi M, Li L, Katabami A, Saito K, Umeno D.

FEBS Lett. 2014 Jan 31;588(3):436-42. doi: 10.1016/j.febslet.2013.12.003. Epub 2013 Dec 10.

5.

Docking and PLS studies on a set of thiophenes RNA polymerase inhibitors against Staphylococcus aureus.

Scotti L, Oliveira Lima Ed, da Silva MS, Ishiki H, Oliveira Lima Id, Oliveira Pereira Fd, Mendonça Junior FJ, Scotti MT.

Curr Top Med Chem. 2014;14(1):64-80.

PMID:
24236725
6.

Evolutionary analysis of the functional plasticity of Staphylococcus aureus C30 carotenoid synthase.

Furubayashi M, Saito K, Umeno D.

J Biosci Bioeng. 2014 Apr;117(4):431-6. doi: 10.1016/j.jbiosc.2013.10.003. Epub 2013 Nov 9.

PMID:
24216462
7.

Inhibition of staphyloxanthin biosynthesis in Staphylococcus aureus by rhodomyrtone, a novel antibiotic candidate.

Leejae S, Hasap L, Voravuthikunchai SP.

J Med Microbiol. 2013 Mar;62(Pt 3):421-8. doi: 10.1099/jmm.0.047316-0. Epub 2012 Dec 14.

PMID:
23242641
8.

Flavone reduces the production of virulence factors, staphyloxanthin and α-hemolysin, in Staphylococcus aureus.

Lee JH, Park JH, Cho MH, Lee J.

Curr Microbiol. 2012 Dec;65(6):726-32. doi: 10.1007/s00284-012-0229-x. Epub 2012 Sep 11.

PMID:
22965624
9.

Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors.

Lee SJ, Lee SJ, Lee SK, Yoon HJ, Lee HH, Kim KK, Lee BJ, Lee BI, Suh SW.

Acta Crystallogr D Biol Crystallogr. 2012 Jul;68(Pt 7):784-93. doi: 10.1107/S0907444912011912. Epub 2012 Jun 15.

PMID:
22751663
10.

Genetic modification in Bacillus subtilis for production of C30 carotenoids.

Maeda I.

Methods Mol Biol. 2012;892:197-205. doi: 10.1007/978-1-61779-879-5_11.

PMID:
22623304
11.

Combined pharmacophore and 3D-QSAR study on a series of Staphylococcus aureus Sortase A inhibitors.

Uddin R, Lodhi MU, Ul-Haq Z.

Chem Biol Drug Des. 2012 Aug;80(2):300-14. doi: 10.1111/j.1747-0285.2012.01403.x. Epub 2012 Jun 11.

PMID:
22553957
12.

Functional expression and extension of staphylococcal staphyloxanthin biosynthetic pathway in Escherichia coli.

Kim SH, Lee PC.

J Biol Chem. 2012 Jun 22;287(26):21575-83. doi: 10.1074/jbc.M112.343020. Epub 2012 Apr 25.

13.

Head-to-head prenyl tranferases: anti-infective drug targets.

Lin FY, Liu YL, Li K, Cao R, Zhu W, Axelson J, Pang R, Oldfield E.

J Med Chem. 2012 May 10;55(9):4367-72. doi: 10.1021/jm300208p. Epub 2012 May 1.

14.

Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase.

Liu CI, Jeng WY, Chang WJ, Ko TP, Wang AH.

J Biol Chem. 2012 May 25;287(22):18750-7. doi: 10.1074/jbc.M112.351254. Epub 2012 Apr 3.

15.

Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics.

Lin FY, Zhang Y, Hensler M, Liu YL, Chow OA, Zhu W, Wang K, Pang R, Thienphrapa W, Nizet V, Oldfield E.

ChemMedChem. 2012 Apr;7(4):561-4. doi: 10.1002/cmdc.201100589. Epub 2012 Jan 30. No abstract available.

16.

Search method for inhibitors of Staphyloxanthin production by methicillin-resistant Staphylococcus aureus.

Sakai K, Koyama N, Fukuda T, Mori Y, Onaka H, Tomoda H.

Biol Pharm Bull. 2012;35(1):48-53.

17.

Discovery of novel selective inhibitors of Staphylococcus aureus β-ketoacyl acyl carrier protein synthase III.

Lee JY, Jeong KW, Shin S, Lee JU, Kim Y.

Eur J Med Chem. 2012 Jan;47(1):261-9. doi: 10.1016/j.ejmech.2011.10.052. Epub 2011 Nov 4.

PMID:
22104972
18.

Squalene synthase inhibitors: An update on the search for new antihyperlipidemic and antiatherosclerotic agents.

Kourounakis AP, Katselou MG, Matralis AN, Ladopoulou EM, Bavavea E.

Curr Med Chem. 2011;18(29):4418-39. Review.

PMID:
21864285
19.

Discovery of atrop fixed alkoxy-aminobenzhydrol derivatives: novel, highly potent and orally efficacious squalene synthase inhibitors.

Ichikawa M, Yokomizo A, Itoh M, Haginoya N, Sugita K, Usui H, Terayama K, Kanda A.

Bioorg Med Chem. 2011 Sep 1;19(17):5207-24. doi: 10.1016/j.bmc.2011.07.007. Epub 2011 Jul 13.

PMID:
21802309
20.

Non-bisphosphonate inhibitors of isoprenoid biosynthesis identified via computer-aided drug design.

Durrant JD, Cao R, Gorfe AA, Zhu W, Li J, Sankovsky A, Oldfield E, McCammon JA.

Chem Biol Drug Des. 2011 Sep;78(3):323-32. doi: 10.1111/j.1747-0285.2011.01164.x. Epub 2011 Aug 3.

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